anti-Decapping Enzyme, Scavenger (DCPS) Antikörper

Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Zusätzlich bieten wir Ihnen Decapping Enzyme, Scavenger Proteine (9) und Decapping Enzyme, Scavenger Kits (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DCPS 28960 Q96C86
DCPS 69305 Q9DAR7
DCPS 266605 Q8K4F7
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Top anti-Decapping Enzyme, Scavenger Antikörper auf antikoerper-online.de

Showing 10 out of 39 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert IHC, IHC (p), WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
$522.50
Details
Human Maus Unkonjugiert ELISA, IF, IHC, IHC (p), WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
$537.17
Details
Human Maus Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
$537.17
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
$537.17
Details
Human Kaninchen Unkonjugiert WB DCPS Antibody (Center)  western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the DCPS antibody detected the DCPS protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$385.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis in NCI-H460 cell line lysates (35ug/lane). 400 μL Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extract of HT-29 cells, using DCPS antibody. Western blot analysis of extracts of HT-29 cells, using DCPS antibody (ABIN4903455) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s. 100 μL Anmelden zum Anzeigen 11 bis 13 Tage
$366.77
Details
Human Maus Unkonjugiert IHC (p), ELISA, WB DCPS monoclonal antibody (M03), clone 3E5 Western Blot analysis of DCPS expression in HeLa . Immunoperoxidase of monoclonal antibody to DCPS on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml] 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Maus Unkonjugiert IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to DCPS on formalin-fixed paraffin-embedded human kidney. [antibody concentration 1.5 ug/ml] Immunofluorescence of monoclonal antibody to DCPS on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert IF, WB DCPS MaxPab rabbit polyclonal antibody. Western Blot analysis of DCPS expression in mouse liver. Western Blot analysis of DCPS expression in transfected 293T cell line by DCPS MaxPab polyclonal antibody.Lane 1: DCPS transfected lysate(38.60 KDa).Lane 2: Non-transfected lysate. 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$425.71
Details

Am meisten referenzierte anti-Decapping Enzyme, Scavenger Antikörper

  1. Human Monoclonal DCPS Primary Antibody für IHC, WB - ABIN2719248 : Wang, Lin, Hou, Chen et al.: Suppression of Lipid Accumulation by Indole-3-Carbinol Is Associated with Increased Expression of the Aryl Hydrocarbon Receptor and CYP1B1 Proteins in Adipocytes and with Decreased ... in International journal of molecular sciences 2016 (PubMed)

  2. Human Polyclonal DCPS Primary Antibody für ICC, IF - ABIN4304527 : Ng, Shboul, Taverniti, Bonnard, Lee, Eskin, Nelson, Al-Raqad, Altawalbeh, Séraphin, Reversade: Loss of the scavenger mRNA decapping enzyme DCPS causes syndromic intellectual disability with neuromuscular defects. in Human molecular genetics 2015 (PubMed)

Weitere Antikörper gegen Decapping Enzyme, Scavenger Interaktionspartner

Human Decapping Enzyme, Scavenger (DCPS) Interaktionspartner

  1. Data show that decapping scavenger enzyme DcpS (DcpS) is a nucleocytoplasmic shuttling protein that activates microRNA (miRNA) degradation.

  2. In DcpS, conformational change is dominated by an anti-symmetric cooperative motion, causing one active site to close as the other opens; however a symmetric motion is also significant.

  3. In vitro decapping assays showed that altered EDC3 is unable to enhance DCP2 decapping at low concentrations and even inhibits DCP2 decapping at high concentration.

  4. DCPS and more generally RNA catabolism, are critical for neurological development, normal cognition and organismal homeostasis in humans.

  5. data demonstrate that DcpS in conjunction with Xrn1 has the potential to regulate RNA stability in a transcript-selective manner in mammalian cells

  6. The central histidine within the DcpS HIT motif is critical for decapping activity and defines the HIT motif as a new mRNA decapping domain, making DcpS the first member of the HIT family of proteins with a defined biological function.

  7. m7GDP breakdown by DcpS should prevent misincorporation of methylated nucleotides in nucleic acids and could generate a unique indicator allowing the cell to monitor mRNA decay.

  8. Structural and biochemical analysis suggests an autoregulatory mechanism whereby premature decapping mRNA is prevented by blocking the conformational changes that are required to form a closed productive active site capable of cap hydrolysis.

  9. crystal structures of DcpS in ligand-free form and in a complex with m7GDP

  10. Furthermore, we show that a novel human histidine triad protein DCS-1, which is expressed together with NR1 in many tissues, can significantly reduce menadione-induced cytotoxicity in these cells

  11. These studies demonstrate that the significance of DcpS extends beyond its well-characterized role in mRNA decay and involves a broader range of functions in RNA processing including nuclear pre-mRNA splicing.

  12. biochemical analysis of the dynamic and mutually exclusive cap hydrolysis activity of the two cap binding sites of DcpS

  13. Data established that DcpS, a key enzyme in mRNA decay, is a new target of DeltaLf transcriptional activity.

Mouse (Murine) Decapping Enzyme, Scavenger (DCPS) Interaktionspartner

  1. Amino acid sequence and xray crystallograpy structure given

Decapping Enzyme, Scavenger (DCPS) Antigen-Profil

Protein Überblick

Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3'->5' exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has no activity towards mRNA molecules longer than 25 nucleotides.

Genbezeichner und Symbole assoziert mit DCPS

  • decapping enzyme, scavenger (DCPS) Antikörper
  • decapping enzyme, scavenger (dcps) Antikörper
  • decapping enzyme, scavenger (Dcps) Antikörper
  • 1700001E16Rik Antikörper
  • AA408441 Antikörper
  • DCPS Antikörper
  • DCS1 Antikörper
  • Hint-5 Antikörper
  • HINT5 Antikörper
  • HSL1 Antikörper

Bezeichner auf Proteinebene für DCPS

decapping enzyme, scavenger , DCS-1 , decapping scavenger enzyme , heat shock-like protein 1 , hint-related 7meGMP-directed hydrolase , histidine triad nucleotide-binding protein 5 , histidine triad protein member 5 , homolog of C. elegans 7meGMP-directed hydrolase dcs-1 , m7GpppX diphosphatase , mRNA decapping enzyme , scavenger mRNA-decapping enzyme DcpS , HINT-5

GENE ID SPEZIES
419716 Gallus gallus
609536 Canis lupus familiaris
100216298 Xenopus (Silurana) tropicalis
28960 Homo sapiens
69305 Mus musculus
266605 Rattus norvegicus
282640 Bos taurus
396689 Sus scrofa
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