Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
DAOA encodes a protein that may function as an activator of D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Zusätzlich bieten wir Ihnen D-Amino Acid Oxidase Activator Kits (8) und D-Amino Acid Oxidase Activator Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 22 products:
Findings showed that NOS1AP (rs348624, rs12742393 and rs1415263), DISC1 (rs821633 and rs1000731), DAOA (rs2391191) and GSK3B (rs6438552) SNPs had no association with development of early-onset schizophrenia; however, our finding suggested statistically significant role of the interaction of NOS1AP, DISC1, DAOA and GSK3B polymorphisms in schizophrenia susceptibility.
In SNP-based single locus association analyses, the rs778292 in the DAOA gene showed significant association with schizophrenia. Additionally, a three-SNP haplotype (rs778292-rs3918342-rs1421292) in the DAOA gene were observed to be significantly associated with schizophrenia in a Taiwanese population.
G72 transgenic mice have larger excitatory synapses with an increased amount of N-methyl-d-aspartate (NMDA) receptors in the molecular layer of dentate gyrus, compared with wild-type littermates. Transgenic animals have lower number of dentate granule cells with a parallel, but an even stronger decrease in the number of excitatory synapses in the molecular layer.
pLG72 interacts with neosynthesized d-amino acid oxidase (zeige DAO Antikörper) (hDAAO), promoting its inactivation and degradation. In this work, we used low-resolution techniques to characterize the surface topology of the hDAAO-pLG72 complex.
Data show that the R30K D-amino acid oxidase activator pLG72 is significantly more prone to degradation than the R30 and the K62E variants in a cell system.
Studies successfully predicted the structures of the N- and C-terminal domains (ND and CD, respectively) of G72.
We suggest that serum G72 protein levels may represent a candidate biomarker for schizophrenia and have confirmed the results of the previous preliminary study.
A Mutation in DAOA Modifies the Age of Onset in PSEN1 (zeige PSEN1 Antikörper) E280A Alzheimer's Disease. Findings strongly suggest that this new conspicuous functional age of onset modifier within the G72 (DAOA) gene could be pivotal for understanding the genetic basis of Alzheimer's disease.
DAOA gene may contribute to the risk for Psychotic disorders and that this gene may play a role as a modulator of executive function.
pLG72 level being significantly increased in the serum of patients with schizophrenia, have led us to propose that the ROS (zeige ROS1 Antikörper) enhancement in mental diseases may be from the overexpression of pLG72 in brain cells.
tadpoles contained high concentrations of D-proline close to the final developmental stage and nearly no D-amino acids were detected in the adult frog, indicating that D-amino acid oxidase (zeige DAO Antikörper) functions in metamorphosis.
This gene encodes a protein that may function as an activator of D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Studies also suggest that one encoded isoform may play a role in mitochondrial function and dendritic arborization. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.
, schizophrenia- and bipolar disorder-associated protein G72
, D-amino-acid oxidase
, D-amino acid oxidase
, D-amino-acid oxidase-like