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Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Zusätzlich bieten wir Ihnen Cyclin L1 Antikörper (52) und Cyclin L1 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
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Results suggest that LEKR1-CCNL1 and IGSF21-KLHDC7A gene polymorphisms influence the development of diabetic retinopathy (DR).
CCNL1 is the target gene of miR-199b-5p.
Data indicate that if the newborn carried a risk allele rs900400 near LEKR/CCNL1, the impact of stress on birth size was stronger.
birth weight lowering effect of the C-allele of rs900400 located near LEKR1 and CCNL1 was replicated in the Danish population. Furthermore the C-allele was associated with increased insulin response following oral glucose stimulation
Data show low birth weight in Asian Indians is not due to variation near CCNL1/ADCY5, but variant ADCY5 is associated with elevated glucose/decreased insulin response which suggests a common genetic cause of low birth weight and risk of type 2 diabetes.
These data demonstrate that there is a fine balance between CCNL1 and TIMP1, which may contribute to breast cancer development.
Our results suggest that a genetic variant of ccnl1 leads to symmetric growth restriction from early pregnancy onward
Cyclin L1 amplification is associated with uterine cervical carcinoma.
variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight
Cyclin L has been shown to associate with the PITSLRE kinase and is involved in pre-mRNA processing.
Our results indicate that CCNL1 plays a critical role in the loco-regional progression of HNSCC and may serve as an indicator for occult advanced tumour stages.
study suggests that cyclin l1 may have a role in RNA processing complex anc ould participate in tumor progression of head and neck squamous cell carcinoma
Data show that a green fluorescent protein (GFP) fusion protein of cyclin L1, in contrast to cyclin L2, was not mobile within the nucleus of living COS7 cells.
CDK11(p110) interacts physically and functionally with cyclin Lalpha and -beta isoforms and SR proteins to regulate splicing.
these findings indicate that CDK11A/B interacts with Cyclin L1 to regulate the cell cycle.
Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21.
cyclin L ania-6a
, cyclin L gamma
, cyclin ania-6a
, cyclin Ania-6a
, cyclin L1
, minichromosome maintenance complex component 2