Coenzyme Q8A Proteine (COQ8A)

COQ8A encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. Zusätzlich bieten wir Ihnen Coenzyme Q8A Antikörper (107) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
COQ8A 56997 Q8NI60
COQ8A 67426 Q60936
Ratte COQ8A COQ8A 360887 Q5BJQ0
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Showing 4 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,355.45
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Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$7,626.01
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Baculovirus infected Insect Cells Human GST tag   50 μg Anmelden zum Anzeigen 10 bis 12 Tage
$624.55
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COQ8A Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
,
Mouse (Murine)

Weitere Proteine zu Coenzyme Q8A (COQ8A) Interaktionspartnern

Human Coenzyme Q8A (COQ8A) Interaktionspartner

  1. Loss of COQ8a results in cerebellar ataxia and coenzyme Q deficiency.

  2. ADCK3/COQ8 localises to mitochondrial cristae and is targeted to this organelle via the presence of an N-terminal localisation signal

  3. work reveals Mg(2 (zeige MUC7 Proteine)+)-dependent ATPase activity of ADCK3, providing strong support for the theoretical prediction of this protein being a functional atypical kinase.

  4. a structural foundation for investigating the role of transmembrane association in regulating the biological activity of ADCK3

  5. Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q biosynthesis.

  6. These observations highlight the importance of screening for a potentially treatable cause, CABC1/ADCK3 mutations

  7. play an important role in mediating p53 (zeige TP53 Proteine)-inducible apoptosis through the mitochondrial pathway.

  8. CABC1 gene mutations in four ubiquinone-deficient patients in three distinct families were reported.

  9. Five additional mutations in ADCK3 were found in three patients with sporadic ataxia, including one known to have CoQ10 deficiency in muscle.

Mouse (Murine) Coenzyme Q8A (COQ8A) Interaktionspartner

  1. Loss of COQ8a results in cerebellar ataxia and coenzyme Q deficiency.

Coenzyme Q8A (COQ8A) Protein Überblick

Protein Überblick

This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found\; however, their full-length nature has not been determined.

Genbezeichner und Symbole assoziert mit Coenzyme Q8A Proteine (COQ8A)

  • coenzyme Q8A (COQ8A)
  • coenzyme Q8A (Coq8a)
  • coenzyme Q8A (coq8a)
  • aarF domain containing kinase 3 (ADCK3)
  • coenzyme Q8B (coq8b)
  • 4632432J16Rik Protein
  • Adck3 Protein
  • adck4 Protein
  • AI462003 Protein
  • ARCA2 Protein
  • cabc1 Protein
  • COQ8 Protein
  • COQ10D4 Protein
  • mKIAA0451 Protein
  • SCAR9 Protein
  • si:dkey-114g7.2 Protein

Bezeichner auf Proteinebene für Coenzyme Q8A Proteine (COQ8A)

aarF domain-containing protein kinase 3 , chaperone activity of bc1 complex-like, mitochondrial , chaperone, ABC1 activity of bc1 complex homolog , coenzyme Q8 homolog , chaperone, ABC1 activity of bc1 complex homolog (S. pombe) , chaperone, ABC1 activity of bc1 complex like , chaperone-ABC1-like , chaperone, ABC1 activity of bc1 complex-like , aarF domain containing kinase 3 , chaperone activity of bc1 complex-like, mitochondrial-like , atypical kinase ADCK3, mitochondrial , AarF domain-containing protein kinase 4 , CG32649-like , Coenzyme Q protein 8B , aarF domain containing kinase 4 , aarF domain-containing protein kinase 4 , atypical kinase COQ8B, mitochondrial , coenzyme Q protein 8B

GENE ID SPEZIES
56997 Homo sapiens
416745 Gallus gallus
480108 Canis lupus familiaris
67426 Mus musculus
360887 Rattus norvegicus
437001 Danio rerio
536925 Bos taurus
100525602 Sus scrofa
100728070 Cavia porcellus
799071 Danio rerio
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