anti-Chromosome 19 Open Reading Frame 40 (C19ORF40) Antikörper

FAAP24 is a component of the Fanconi anemia (FA) core complex (see MIM 227650), which plays a crucial role in DNA damage response (Ciccia et al., 2007 [PubMed 17289582]).[supplied by OMIM, Mar 2008].. Zusätzlich bieten wir Ihnen Chromosome 19 Open Reading Frame 40 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
C19ORF40 91442 Q9BTP7
C19ORF40 101831 Q8BHL6
C19ORF40    
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Top anti-Chromosome 19 Open Reading Frame 40 Antikörper auf antikoerper-online.de

Showing 7 out of 11 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of MCF7 cells, using C19orf40 antibody. 100 μL Anmelden zum Anzeigen 11 bis 13 Tage
$366.77
Details
Human Kaninchen Unkonjugiert WB Western Blot: FAAP24 Antibody [NBP2-16398] - A: 293T. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$516.98
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: FAAP24 Antibody [NBP1-91876] - Staining of human oral mucosa shows strong nuclear positivity in squamous epithelial cells. Immunocytochemistry/Immunofluorescence: FAAP24 Antibody [NBP1-91876] - Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli & vesicles. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$494.38
Details
Human Kaninchen Unkonjugiert IF, IHC (p) Immunohistochemical staining of human oral mucosa with C19orf40 polyclonal antibody  shows strong nuclear positivity in squamous epithelial cells. Immunofluorescent staining of human cell line U-2 OS with C19orf40 polyclonal antibody  at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli and vesicles. 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$637.32
Details
Human Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
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Human Kaninchen Unkonjugiert WB   200 μL Anmelden zum Anzeigen 10 bis 11 Tage
$491.79
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 11 bis 16 Tage
$405.08
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Weitere Antikörper gegen Chromosome 19 Open Reading Frame 40 Interaktionspartner

Human Chromosome 19 Open Reading Frame 40 (C19ORF40) Interaktionspartner

  1. This is the first report of an FAAP24 loss of function mutation found in human patients with EBV-associated lymphoproliferation.

  2. These results demonstrate dual roles of FAAP24 in DNA damage response against crosslinking lesions, one through the formation of FANCM/FAAP24 heterodimer and the other via its ssDNA-binding activity required in optimized checkpoint activation.

  3. Crystal structure of the FANCM-FAAP24 complex.

  4. Results show that the first HhH motif of FAAP24 is a potential binding site for DNA, which plays a critical role in targeting FANCM-FAAP24 to chromatin.

  5. FANCM and FAAP24 play multiple, while not fully epistatic, roles in maintaining genomic integrity.

  6. FANCM/FAAP24 plays a role in ICL-induced checkpoint activation through regulating RPA recruiment at ICL-stalled replication forks.

  7. FAAP24 targets FANCM to structures that mimic intermediates formed during the replication/repair of damaged DNA.

  8. FANCM is an anchor required for recruitment of the FA core complex to chromatin, and the FANCM/FAAP24 interaction is essential for this chromatin-loading activity

  9. FAAP24 is dispensable for DNA binding and branch migration activity of FANCM.

  10. DNA damage recognition and remodeling activities of FANCM and FAAP24 cooperate to promote efficient activation of DNA damage checkpoints in Fanconi anemia.

Chromosome 19 Open Reading Frame 40 (C19ORF40) Antigen-Profil

Protein Überblick

FAAP24 is a component of the Fanconi anemia (FA) core complex (see MIM 227650), which plays a crucial role in DNA damage response (Ciccia et al., 2007

Genbezeichner und Symbole assoziert mit C19ORF40

  • Fanconi anemia core complex associated protein 24 (FAAP24) Antikörper
  • Fanconi anemia core complex associated protein 24 (Faap24) Antikörper
  • AW124591 Antikörper
  • AW538696 Antikörper
  • Faap24 Antikörper

Bezeichner auf Proteinebene für C19ORF40

Fanconi anemia-associated protein of 24 kDa , Fanconi anemia-associated protein, 24 kDa

GENE ID SPEZIES
510793 Bos taurus
91442 Homo sapiens
101831 Mus musculus
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