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may act as a subunit of a neuronal nicotinic acetylcholine receptor. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal CHRNB4 Primary Antibody für WB - ABIN1881200
Zhang, Kranzler, Poling, Gelernter: Variation in the nicotinic acetylcholine receptor gene cluster CHRNA5-CHRNA3-CHRNB4 and its interaction with recent tobacco use influence cognitive flexibility. in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2010
Show all 4 Pubmed References
Human Polyclonal CHRNB4 Primary Antibody für ELISA, WB - ABIN560371
Rezvani, Teng, De Biasi: The ubiquitin-proteasome system regulates the stability of neuronal nicotinic acetylcholine receptors. in Journal of molecular neuroscience : MN 2010
Cow (Bovine) Polyclonal CHRNB4 Primary Antibody für ELISA - ABIN451672
Liang, Salas, Marubio, Bercovich, De Biasi, Beaudet, Dani: Functional polymorphisms in the human beta4 subunit of nicotinic acetylcholine receptors. in Neurogenetics 2005
our results show that a genomic region with functionally related genes, such as the CHRNA5/CHRNA3/CHRNB4 cluster, is under coordinated regulatory control.
The results of this study suggests a pleiotropic role of Chr15q25 CHRNA5-CHRNA3-CHRNB4 gene cluster with complex influences in ADHD, tobacco smoking and cognitive performance.
focus on the CHRNA5/A3/B4 gene cluster and its role in nicotine dependence (review)
MAFA controls autonomic nervous system-mediated insulin secretion by activating the transcription of nicotinic (ChrnB2 and ChrnB4) receptor genes, which is impaired in patients with type 2 diabetes.
Our data suggest that gene variance in the CHRNA5 (zeige CHRNA5 Antikörper)-CHRNA3 (zeige CHRNA3 Antikörper)-CHRNB4 cluster is associated with an increased risk of death, incidence of COPD (zeige ARCN1 Antikörper) and tobacco-related cancer in smokers.
two SNPs (rs6495308 and rs11072768) in CHRNA5-A3-B4 have a indirect effect on lung cancer through smoking behaviors
Data suggest that CHRNA5-A3-B4 gene variants do not exhibit a robust association with smoking cessation and are unlikely to be useful for clinically optimizing smoking cessation pharmacotherapy for Caucasian smokers.
CHRNA5-A3-B4 genotype associates with body mass index in never smokers.
Identified a novel exon variant Ser140Gly of CHRNB4 , and validated two previously reported variants Tyr215Tyr and Asp398Asn are significantly associated with COPD (zeige ARCN1 Antikörper) risk in Chinese.
Study provides new evidence that the overexpression of the CHRNA5/A3/B4 region disrupts pyramidal neuronal structure in the hippocampus, and thus affecting the cognitive capacities
Data suggest that the nicotinic acetylcholine receptor beta4 subunit (beta4 subunit) is not involved in ethanol responses.
MAFA controls autonomic nervous system-mediated insulin secretion by activating the transcription of nicotinic (ChrnB2 and ChrnB4) receptor genes, which is impaired in type 2 diabetes.
The alpha3beta4* nicotinic ACh (zeige FGFR3 Antikörper) receptor subtype mediates physical dependence to morphine
Downregulation of nAChR (zeige CHRNA4 Antikörper) subunit and PSD-93 (zeige DLG2 Antikörper) expression after cavernous nerve injury, or even manipulation, could interrupt synaptic transmission within the MPG (zeige MPG Antikörper) and thus contribute to the loss of neural control of urogenital organs after pelvic surgeries.
findings suggest an important role for the a3b4* nAChR (zeige CHRNA4 Antikörper) subtype in nicotine reward and physical aspects of the nicotine withdrawal syndrome.
Chrnb4 is involved in anxiety- and perhaps depression-like behaviors and contribute to the analgesic effects of nicotine.
At higher doses, varenicline is an agonist of Chrnb4 producing physiological changes in mice.
the present results indicate an important role for Chrna7 and Chrnb4 -containing nicotinic acetylcholine receptors in the anhedonic or somatic signs of nicotine withdrawal
Polymorphisms located within the Chrna5-Chrna3-Chrnb4 cluster on mouse chromosome 9 were found to co-segregate with alcohol preference, with high-drinking F(2) mice carrying B6 alleles and low-drinking F(2) mice carrying D2 alleles.
The involvement of the beta4 nAChR (zeige CHRNA4 Antikörper) subunit in both core body temperature homeostasis and nicotine-elicited thermo-alterations in mice.
may act as a subunit of a neuronal nicotinic acetylcholine receptor
acetylcholine receptor, nicotinic, beta 4 (neuronal)
, cholinergic receptor, nicotinic, beta polypeptide 4
, neuronal acetylcholine receptor subunit beta-4
, neuronal nicotinic receptor beta 4 subunit
, Acetylcholine receptor beta 4
, N-alpha 2
, neuronal acetylcholine receptor non-alpha-2 chain
, nicotinic acetylcholine receptor beta4 subunit
, N-alpha 3
, neuronal acetylcholine receptor non-alpha-3 chain
, nicotinic acetylcholine receptor beta-4 (non-alpha-3) subunit
, cholinergic receptor, nicotinic, beta 4