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CBLN4 encodes a member of a family of small secreted proteins containing C1Q domains.
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Results show that Cbln1 (zeige CBLN1 Proteine), Cbln2, and Cbln4 are abundantly expressed in nearly all brain regions, but exhibit strikingly different expression patterns and developmental dynamics. Using newly generated knockin reporter mice for Cbln2 and Cbln4, we find that Cbln2 and Cbln4 are not universally expressed in all neurons, but only in specific subsets of neurons.
SRY (zeige SRY Proteine) and SOX9 (zeige SOX9 Proteine) contribute to the male-specific upregulation of Cbln4 in the developing testis.
This gene encodes a member of a family of small secreted proteins containing C1Q domains. Members of this family are involved in regulation of neurexin signalling during synapse development. The mouse homolog of the protein encoded by this gene competes with netrin to bind to the deleted in colorectal cancer receptor.
, cerebellin 4 precursor
, cerebellin precursor-like 1
, cerebellin-like glycoprotein 1
, cerebellin 4 precursor protein