Calcium and Integrin-Binding Protein 1 (CIB1) ELISA Kits

CIB1 encodes a member of the EF-hand domain-containing calcium-binding superfamily. Zusätzlich bieten wir Ihnen CIB1 Antikörper (121) und CIB1 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
CIB1 10519 Q99828
CIB1 23991 Q9Z0F4
CIB1 81823 Q9R010
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Maus
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$875.60
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Human
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$875.60
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Ratte
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$875.60
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Rind (Kuh)
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$1,029.60
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Weitere ELISA Kits für CIB1 Interaktionspartner

Human Calcium and Integrin-Binding Protein 1 (CIB1) Interaktionspartner

  1. Results suggest that interaction of CIB1 with alphaIIb is one of the early events occurring during outside-in signaling. Furthermore, CIB1 recruits FAK to the alphaIIbbeta3 complex at the filopodia where FAK is activated, which in turn activates c-Src, resulting in propagation of outside-in signaling leading to platelet spreading.

  2. we found that ectopic expression of oncogenic KRas and HRas (zeige HRAS ELISA Kits) in cells resulted in elevated CIB1 expression. We previously described the Ca(2 (zeige CA2 ELISA Kits)+)-myristoyl switch function of CIB1, and its ability to facilitate agonist-induced plasma membrane localisation of sphingosine kinase 1 (SK1 (zeige SPHK1 ELISA Kits)), a location where SK1 (zeige KCNN1 ELISA Kits) is known to elicit oncogenic signalling.

  3. a large subset of TNBCs depend on CIB1 for cell survival and tumor growth, independent of CIB1 expression levels.

  4. mRNA and protein expression levels of CIB1 were decreased in the oligoasthenozoospermia patients.CIB1 may be involved in the pathogenesis of oligoasthenozoospermia by the CDK1 (zeige CDK1 ELISA Kits) signaling pathway.

  5. High serum CIB1 levels are associated with pancreatic cancer.s

  6. KIP binding to TRF2 (zeige TERF2 ELISA Kits) enhances the telomere-binding activity of TRF2 (zeige TERF2 ELISA Kits), suggesting that KIP acts as a positive regulator of TRF2 (zeige TERF2 ELISA Kits) function.

  7. these studies suggested that Kaposi's sarcoma-associated herpesvirus utilizes CIB1 as one of the key molecule(s) to coordinate and sustain the EphA2 (zeige EPHA2 ELISA Kits) mediated signaling involved in its entry

  8. CIB1a is a novel mediator of PKD2 (zeige PKD2 ELISA Kits)-driven carcinogenesis.

  9. we present data that show that CIB1 binds to seven additional alpha-integrin CT peptides, bringing the total number of alpha-integrins that can associate with CIB1 to eight.

  10. Results indicate that CIB1 is uniquely positioned to regulate PI3K (zeige PIK3CA ELISA Kits)/AKT (zeige AKT1 ELISA Kits) and MEK (zeige MAP2K1 ELISA Kits)/ERK (zeige EPHB2 ELISA Kits) signaling and that simultaneous disruption of these pathways synergistically induces a nuclear GAPDH (zeige GAPDH ELISA Kits)-dependent cell death.

Mouse (Murine) Calcium and Integrin-Binding Protein 1 (CIB1) Interaktionspartner

  1. results suggest that interaction of CIB1 with alphaIIb is one of the early events occurring during outside-in signaling. Furthermore, CIB1 recruits FAK to the alphaIIbbeta3 complex at the filopodia where FAK is activated, which in turn activates c-Src, resulting in propagation of outside-in signaling leading to platelet spreading.

  2. CIB1 is involved in regulating endomitosis, perhaps through its interaction with Polo-like kinase 3 (zeige PLK3 ELISA Kits)

  3. Data demonstrate that CIB1 is not required for AID to mediate antibody gene diversification processes. It remains possible that CIB1 has an alternative, a redundant or a subtle non-limiting regulatory role in AID biology.

  4. CIB1 functions as a previously undescribed regulator of cardiac hypertrophy through its ability to regulate the association of calcineurin with the sarcolemma and its activation.

  5. CIB1 is a key regulator of thrombosis, by affecting platelet spreading, but not platelet filopodia formation.

  6. CIB co-immunoprecipitated with Snk (zeige ATP1A4 ELISA Kits) and inhibited the kinase activity of Snk (zeige ATP1A4 ELISA Kits), suggesting that CIB is a negative regulator for Snk (zeige ATP1A4 ELISA Kits) kinase activity.

  7. MEFs derived from Cib1(-/-) mice exhibit a much slower growth rate compared to Cib1(+/+) MEFs, suggesting that CIB1 regulates the cell cycle, differentiation of spermatogenic germ cells, and/or differentiation of supporting Sertoli cells.

  8. loss of CIB1 in endothelial cells decreases p21-activated kinase 1 (zeige PAK1 ELISA Kits) activation, downstream extracellular signal-regulated kinase 1/2 (zeige MAPK3 ELISA Kits) activation, and matrix metalloproteinase 2 (zeige MMP2 ELISA Kits) expression, all of which are known to contribute to angiogenesis.

CIB1 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the EF-hand domain-containing calcium-binding superfamily. The encoded protein interacts with many other proteins, including the platelet integrin alpha-IIb-beta-3, DNA-dependent protein kinase, presenilin-2, focal adhesion kinase, p21 activated kinase, and protein kinase D. The encoded protein may be involved in cell survival and proliferation, and is associated with several disease states including cancer and Alzheimer's disease. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit CIB1

  • calcium and integrin binding 1 (calmyrin) (cib1) Antikörper
  • calcium and integrin-binding protein 1 (CpipJ_CPIJ003501) Antikörper
  • calcium and integrin binding 1 (CIB1) Antikörper
  • calcium and integrin binding 1 (cib1) Antikörper
  • Calcium and integrin-binding protein 1 (kip1) Antikörper
  • calcium and integrin binding 1 (calmyrin) (Cib1) Antikörper
  • calcium and integrin binding 1 (Cib1) Antikörper
  • Cib Antikörper
  • Cibkip Antikörper
  • CIBP Antikörper
  • Kip Antikörper
  • KIP1 Antikörper
  • Prkdcip Antikörper
  • Sip2-28 Antikörper
  • zgc:112015 Antikörper

Bezeichner auf Proteinebene für CIB1

calcium and integrin-binding protein 1 , calcium and integrin binding protein 1 , Calcium and integrin-binding protein 1 , DNA-PK interaction protein , DNA-PKcs-interacting protein , DNA-dependent protein kinase interacting protein , SNK-interacting protein 2-28 , CIB , calcium and integrin binding, protein kinase interacting protein , calmyrin , kinase-interacting protein , protein kinase, DNA activated, catalytic polypeptide interacting protein , KIP , calcium- and integrin-binding protein

GENE ID SPEZIES
550376 Danio rerio
6034872 Culex quinquefasciatus
100141300 Ovis aries
100286603 Salmo salar
100301714 Oncorhynchus mykiss
10519 Homo sapiens
23991 Mus musculus
81823 Rattus norvegicus
479044 Canis lupus familiaris
100157484 Sus scrofa
510141 Bos taurus
100726412 Cavia porcellus
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