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CALCOCO2 encodes a coiled-coil domain-containing protein. Zusätzlich bieten wir Ihnen Calcium Binding and Coiled-Coil Domain 2 Antikörper (105) und viele weitere Produktgruppen zu diesem Protein an.
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findings reveal a negative feedback loop of RLR (zeige DHX58 Proteine) signaling generated by Tetherin (zeige BST2 Proteine)-MARCH8 (zeige MARCH8 Proteine)-MAVS (zeige MAVS Proteine)-NDP52 axis and provide insights into a better understanding of the crosstalk between selective autophagy and optimal deactivation of type I IFN signaling.
The authors propose that Rab35 (zeige RAB35 Proteine)-GTP (zeige AK3 Proteine) is a critical regulator of autophagy through recruiting autophagy receptor NDP52.
The authors identify calcium-binding and coiled-coil domain 2 (CALCOCO2, also known as NDP52) as a binding partner of influenza A virus PB1 (zeige SMR3A Proteine)-F2.
Presence of the NDP52 rs2303015 minor variant increases the risk for spontaneous bacterial peritonitis in patients with alcoholic cirrhosis.
insight into how CALCOCO2 targets ubiquitin-decorated pathogens for autophagic degradations
These data show that NDP52 promotes the maturation of autophagosomes via its interaction with LC3A (zeige MAP1LC3A Proteine), LC3B (zeige MAP1LC3B Proteine), and/or GABARAPL2 (zeige GABARAPL2 Proteine) through a distinct LC3 (zeige MAP1LC3A Proteine)-interacting region, and with MYOSIN VI (zeige MYO6 Proteine).
data support a model in which non-ND10 resident Sp100 (zeige SP100 Proteine) acts as a negative regulator of polycomb (zeige CBX2 Proteine) repressive complex-2 (PRC2) recruitment, and suggest that KSHV may actively escape ND10 silencing mechanisms to promote establishment of latent chromatin.
two receptors previously linked to xenophagy, NDP52 and optineurin (zeige OPTN Proteine), are the primary receptors for PINK1 (zeige PINK1 Proteine)- and parkin (zeige PARK2 Proteine)-mediated mitophagy
Dimeric NDP52 forms a ternary complex with two monomeric galectin-8 (zeige LGALS8 Proteine) molecules as well as two LC3C (zeige MAP1LC3C Proteine) molecules
The missense SNP rs2303015 (Val248Ala) in the NDP52 was associated with Crohn's disease.
expression and association of NDP52 with autophagy-regulated gene proteins including LC3 (zeige MAP1LC3A Proteine), as well as phosphorylated tau and amyloid-beta in brains of an Alzheimer disease model
The authors conclude that the dispersion of ND10 by major immediate-early (zeige JUN Proteine) protein 1 (IE1) appears not to be important for murine cytomegalovirus replication in a mouse-cell culture.
This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a receptor for ubiquitin-coated bacteria and plays an important role in innate immunity by mediating macroautophagy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
calcium binding and coiled-coil domain 2
, Calcium-binding and coiled-coil domain-containing protein 2
, antigen nuclear dot 52 kDa protein
, calcium-binding and coiled-coil domain-containing protein 2
, nuclear domain 10 protein 52
, nuclear domain 10 protein NDP52
, nuclear dot protein 52
, nuclear domain 10 protein 52 like 1