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CMTM4 belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. Zusätzlich bieten wir Ihnen CMTM4 Kits (27) und CMTM4 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 34 products:
Human Polyclonal CMTM4 Primary Antibody für IHC, IHC (p) - ABIN4299310
Bei, Zhang, Wei, Zhu, Wang, Zeng, Chen, Tan: Clinical significance of CMTM4 expression in hepatocellular carcinoma. in OncoTargets and therapy 1970
CMTM6 (zeige CMTM6 Antikörper) is present at the cell surface, associates with the PD-L1 (zeige CD274 Antikörper) protein, reduces its ubiquitination and increases PD-L1 (zeige CD274 Antikörper) protein half-life; CMTM6 (zeige CMTM6 Antikörper) enhances the ability of PD-L1 (zeige CD274 Antikörper)-expressing tumour cells to inhibit T cells; collectively, our data reveal that PD-L1 (zeige CD274 Antikörper) relies on CMTM6 (zeige CMTM6 Antikörper)/4 to efficiently carry out its inhibitory function, and suggest potential new avenues to block this pathway
CMTM4 is downregulated and exhibits tumour-suppressor activities in clear cell renal cell carcinoma (zeige MOK Antikörper), and could be exploited as a target for clear cell renal cell carcinoma (zeige MOK Antikörper) treatment.
Data show that CMTM4 might be an important gene involved in cell growth and cell cycle regulation.
Bioinformatics based on CKLF2 (zeige CKLF Antikörper) cDNA and protein sequences in combination with experimental validation identified CKLFSF1 (zeige CMTM1 Antikörper)-8 gene clusters, between the SCY (zeige CELSR1 Antikörper) and the TM4SF (zeige TSPAN1 Antikörper) gene families. The 8 family members were cloned and characterized.
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. Alternatively spliced transcript variants encoding different isoforms have been identified.
CKLF-like MARVEL transmembrane domain-containing protein 4
, chemokine-like factor super family 4
, chemokine-like factor superfamily member 4
, chemokine-like factor superfamily 4