Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 Proteine (BLOC1S1)

BLOC1S1 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. Zusätzlich bieten wir Ihnen BLOC1S1 Antikörper (17) und BLOC1S1 Kits (13) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
BLOC1S1 2647 P78537
BLOC1S1 288785 D3ZKU7
BLOC1S1 14533 O55102
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Showing 10 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,744.22
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,744.22
Details
Escherichia coli (E. coli) Human GST tag Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 (BLOC1S1) (AA 1-153), (full length) protein (GST tag) 50 μg Anmelden zum Anzeigen 13 bis 16 Tage
$242.00
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Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$225.40
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$554.07
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Hefe Xenopus tropicalis His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,253.17
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,253.17
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,253.17
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Hefe Arabidopsis thaliana His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,337.50
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Hefe Orang-Utan His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,339.33
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BLOC1S1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Rat (Rattus)

Mouse (Murine)

Weitere Proteine zu Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 (BLOC1S1) Interaktionspartnern

Human Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 (BLOC1S1) Interaktionspartner

  1. Using cancer cell lines, the study shows that BLOC1S1 mRNA is specifically cleaved by IRE1 (zeige ERN1 Proteine) at guanine 444, but only under conditions of IRE1 (zeige ERN1 Proteine) hyperactivation.

  2. The Hermansky-Pudlak syndrome complex BLOC-1 and its cargo PI4KIIalpha interact with regulators of the actin cytoskeleton.

  3. BLOS1 interacts with KXD1.

  4. GCN5L1/BLOC1S1 regulates lysine acetylation in mitochondria.

  5. Quantitative proteomic studies expand the functional repertoire of the BLOC-1 complex and provide insight into putative molecular pathways of schizophrenia susceptibility.

  6. Together this study data provide evidence for the involvement of the BLOC-1 protein complex in SZ pathogenesis.

  7. Experimental investigation of five specific genes, AP3B1 (zeige AP3B1 Proteine), ATP6AP1 (zeige ATP6AP1 Proteine), BLOC1S1, LAMP2 (zeige LAMP2 Proteine), and RAB11A (zeige RAB11A Proteine), has confirmed novel roles for these proteins in the proper initiation of macroautophagy in amino acid-starved fibroblasts.

  8. Biogenesis of Lysosome-related Organelles co (zeige SNAPIN Proteine)mplex-1 (BLOC-1) subunit 1 (BLOS1).

Mouse (Murine) Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 (BLOC1S1) Interaktionspartner

  1. Data show that the mitochondrial enriched GCN5 (zeige KAT2A Proteine)-like 1 protein (GCN5L1) controls hepatic glucose production by regulating FoxO1 (zeige FOXO1 Proteine) protein levels.

  2. Acetylation of cardiac mitochondrial fatty acid oxidation enzymes by GCN5L1 significantly upregulates their activity in diet-induced obese mice.

  3. TDH, responsible for mitochondrial production of acetyl-CoA (zeige LPCAT1 Proteine) in mouse embryonic stem cells, and the acetyltransferase GCN5L1 cooperate to acetylate Lys501 in KBP, allowing its recognition by and degradation via Fbxo15 (zeige FBXO15 Proteine), an F-box protein (zeige FBXO30 Proteine) transcriptionally controlled by the pluripotency core factors and repressed following differentiation.

  4. BLOS1 interacts with sorting nexin 2 (zeige SNX2 Proteine) and the ESCRT-I (zeige VPS28 Proteine) component TSG101 (zeige TSG101 Proteine) to mediate the sorting of EGFR (zeige EGFR Proteine) into endosomal compartments

  5. Here we show that genetic deletion of GCN5L1 has a direct positive effect on the expression and activity of Transcriptional Factor EB (TFEB (zeige TFEB Proteine)), which acts as a master regulator of autophagy.

  6. Mutations in the human genes encoding Snapin (zeige SNAPIN Proteine) and the BLOS proteins could underlie novel forms of Hermansky-Pudlak syndrome as seen in mouse models

  7. Defects in all the 5 known components of BLOC-1 (zeige PLDN Proteine), including RP, cause severe Hermansky Pudlak syndrome in mice, suggesting that the subunits are nonredundant and that BLOC-1 (zeige PLDN Proteine) plays a key role in organelle biogenesis.

  8. These results indicate that the BLOC-1 (zeige PLDN Proteine) and AP-3 (zeige AP3B1 Proteine) protein complexes affect the targeting of SNARE (zeige VTI1B Proteine) and non-SNARE (zeige VTI1B Proteine) AP-3 (zeige AP3B1 Proteine) cargoes and suggest a function of the BLOC-1 (zeige PLDN Proteine) complex in membrane protein sorting.

BLOC1S1 Protein Überblick

Protein Überblick

BLOC1S1 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules (Starcevic and Dell'Angelica, 2004

Genbezeichner und Symbole assoziert mit BLOC1S1

  • biogenesis of lysosomal organelles complex 1 subunit 1 (BLOC1S1)
  • biogenesis of lysosomal organelles complex-1, subunit 1 (Bloc1s1)
  • AI839753 Protein
  • BLOS1 Protein
  • Gcn5l1 Protein
  • MICoA Protein
  • RT14 Protein

Bezeichner auf Proteinebene für BLOC1S1

BLOC subunit 1 , BLOC-1 subunit 1 , GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 1 , GCN5 general control of amino-acid synthesis 5-like 1 , GCN5-like protein 1 , MTA1-interacting coactivator , biogenesis of lysosome-related organelles complex 1 subunit 1 , biogenesis of lysosome-related organelles complex-1, subunit 1 , GCN5 general control of amino acid synthesis-like 1 , general control of amino acid synthesis, yeast homolog-like 1 , general control of amino acid synthesis-like 1

GENE ID SPEZIES
2647 Homo sapiens
615149 Bos taurus
288785 Rattus norvegicus
100190807 Pongo abelii
14533 Mus musculus
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