BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) ELISA Kits

The protein encoded by BAP1 localizes to the nucleus and it interacts with the RING finger domain of the breast cancer 1, early onset protein (BRCA1). Zusätzlich bieten wir Ihnen BAP1 Antikörper (128) und BAP1 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human BAP1 BAP1 8314 Q92560
BAP1 306257 D3ZHS6
Anti-Maus BAP1 BAP1 104416 Q99PU7
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Top BAP1 ELISA Kits auf antikoerper-online.de

Showing 3 out of 4 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Ratte 0.094 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$590.00
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Rind (Kuh)
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$1,029.60
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Huhn
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$1,095.60
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Weitere ELISA Kits für BAP1 Interaktionspartner

Human BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) Interaktionspartner

  1. Our findings suggest that the genetic profile of coexistent GNAQ (zeige GNAQ ELISA Kits) or GNA11 (zeige GNA11 ELISA Kits) mutations with BAP1 (zeige RNF2 ELISA Kits) or SF3B1 mutations can aid the histopathological diagnosis of blue nevus-like melanoma and distinguish blue nevus-like melanoma from conventional epidermal-derived melanomas.

  2. Intratumoral heterogeneity of BAP1 (zeige RNF2 ELISA Kits) protein expression is more frequent in primary tumor than in metastatic sites. The loss of BAP1 (zeige RNF2 ELISA Kits) protein expression in metastatic sites predicts poor prognosis in patients with ccRCC.

  3. this review discusses BAP1 (zeige RNF2 ELISA Kits) as a drug target in mesothelioma

  4. Loss of nuclear BAP1 (zeige RNF2 ELISA Kits) expression is an independent prognostic factor of poor overall survival and associated with distant metastasis in oral mucosal melanoma.

  5. In malignant peritoneal mesothelioma, the most frequent genetic alteration was biallelic inactivation of the BAP1 (zeige RNF2 ELISA Kits) gene, which occurred in 9/13 cases, with an additional two cases demonstrating monoallelic loss of BAP1 (zeige RNF2 ELISA Kits). All 11 of these cases demonstrated loss of BAP1 (zeige RNF2 ELISA Kits) nuclear staining by immunohistochemistry

  6. BAP1 (zeige RNF2 ELISA Kits) mutations and other canonical genomic aberrations usually arise in an early punctuated burst in uveal melanoma.

  7. BRCA1-associated protein 1 (BAP1) gene mutation status had no prognostic significance. The frequency and spectrum of BAP1 (zeige RNF2 ELISA Kits) mutations in UM may be more dependent on ethnicity and demographic variables than hitherto considered.

  8. study reports germline mutations of the BAP1 (zeige RNF2 ELISA Kits) gene in a sample of 1977 melanoma patients and 754 controls; sequencing revealed 30 BAP1 (zeige RNF2 ELISA Kits) variants in total, of which 27 were rare; of the 27 rare variants, 22 were present in cases (18 missense, 1 splice acceptor, 1 frameshift and 2 near splice regions) and 5 in controls (all missense)

  9. A deleterious mutation of BAP1 (zeige RNF2 ELISA Kits) was confirmed in 12/17 melanocytic BAP1 (zeige RNF2 ELISA Kits)-associated intradermal tumors cases.

  10. Although there have been reports of sarcomas and meningiomas in patients affected with BAP1 (zeige RNF2 ELISA Kits) mutations, to our knowledge malignant peripheral nerve sheath tumors in this patient population have not been previously reported. We report a case of malignant peripheral nerve sheath tumor in a patient affected by a BAP1 (zeige RNF2 ELISA Kits) mutation.

Mouse (Murine) BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) Interaktionspartner

  1. Bap1 as a metabolic regulator in liver and pancreas.

  2. BAP1(+/-) mice exposed to low-dose asbestos fibers showed an altered peritoneal inflammatory response and higher levels of pro-tumorigenic alternatively polarized M2 macrophages, and lower cytokine levels. They had a higher incidence of mesothelioma.

  3. Bap1 loss led to a fully penetrant myeloproliferative disease with splenomegaly, leukocytosis, anemia and progenitor expansion via alterations in histone methylation and gene expression.

  4. INO80 is stabilized and targeted to replication forks by BAP1 during normal DNA synthesis but downregulated in BAP1 defective cancer cells

  5. Both Vhl (zeige VHL ELISA Kits) and Bap1 are required for kidney function. Inactivation of Bap1 in neprhon progenitor cells causes renal failure earlier than Vhl (zeige VHL ELISA Kits) inactivation. Bap1 is also a stronger tumor suppressor gene than Vhl (zeige VHL ELISA Kits) in the kidney.

  6. Drawing parallels to human disease, these unbiased genetic findings indicate that BAP1 mutation carriers are predisposed to the tumorigenic effects of asbestos and suggest that high penetrance of mesothelioma requires such environmental exposure.

  7. results identify a potent tumor suppressor function for BAP1 in myeloid neoplasia; propose that BAP1 forms a core complex with HCF-1 (zeige HCFC1 ELISA Kits) and OGT (zeige OGT ELISA Kits) that can differentially recruit additional histone-modifying enzymes to regulate gene expression and preserve norm

  8. Bap1 helps to control cell proliferation by regulating HCF-1 (zeige HCFC1 ELISA Kits) protein levels and by associating with genes involved in the G(1)-S transition

BAP1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene localizes to the nucleus and it interacts with the RING finger domain of the breast cancer 1, early onset protein (BRCA1). This gene is thought to be a tumor suppressor gene that functions in the BRCA1 growth control pathway. There are multiple polyadenylation sites found in this gene.

Genbezeichner und Symbole assoziert mit BAP1

  • BRCA1 associated protein 1 (BAP1) Antikörper
  • Brca1 associated protein 1 (Bap1) Antikörper
  • BRCA1 associated protein 1 L homeolog (bap1.L) Antikörper
  • BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (bap1) Antikörper
  • BRCA1 associated protein 1 (Bap1) Antikörper
  • 2300006C11Rik Antikörper
  • AA989761 Antikörper
  • AW553466 Antikörper
  • BAIAP3 Antikörper
  • hucep-6 Antikörper
  • hucep-13 Antikörper
  • mKIAA0272 Antikörper
  • si:dkey-42i9.9 Antikörper
  • uch-x4 Antikörper
  • uchl2 Antikörper

Bezeichner auf Proteinebene für BAP1

cerebral protein 6 , cerebral protein-13 , ubiquitin carboxyl-terminal hydrolase BAP1 , BAI1-associated protein 3 , BRCA1-associated protein 1 , ubiquitin carboxy-terminal hydrolase , Brca1 associated protein 1 , ubiquitin C-terminal hydrolase X4 , BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)

GENE ID SPEZIES
8314 Homo sapiens
100124510 Bos taurus
306257 Rattus norvegicus
484737 Canis lupus familiaris
104416 Mus musculus
415944 Gallus gallus
734438 Xenopus laevis
558885 Danio rerio
100731081 Cavia porcellus
100051934 Equus caballus
100154798 Sus scrofa
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