Anoctamin 1, Calcium Activated Chloride Channel Proteine (ANO1)

Acts as a calcium-activated chloride channel. Zusätzlich bieten wir Ihnen ANO1 Antikörper (333) und ANO1 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
ANO1 55107 Q5XXA6
ANO1 101772 Q8BHY3
Ratte ANO1 ANO1 309135  
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Top ANO1 Proteine auf antikoerper-online.de

Showing 6 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,744.22
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,744.22
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 60 bis 65 Tage
$6,628.57
Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 60 bis 65 Tage
$9,444.73
Details
Escherichia coli (E. coli) Maus His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$704.00
Details
Escherichia coli (E. coli) Human Unkonjugiert   5 applications Anmelden zum Anzeigen 1 bis 2 Tage
$312.71
Details

ANO1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine) ,
, ,

Weitere Proteine zu Anoctamin 1, Calcium Activated Chloride Channel (ANO1) Interaktionspartnern

Guinea Pig Anoctamin 1, Calcium Activated Chloride Channel (ANO1) Interaktionspartner

  1. Antigen challenge and Calcium-dependent agonist treatment increased Chloride ion transport via the overexpression of TMEM16A in goblet cell metaplasia in a guinea-pig asthma model

Human Anoctamin 1, Calcium Activated Chloride Channel (ANO1) Interaktionspartner

  1. Data show that ANO1 in peripheral blood is of clinical potential for monitoring recurrence and evaluating therapeutic efficacy of imatinib for GIST patients.

  2. Results show that TMEM16A is a direct target of miR (zeige MLXIP Proteine)-381 and its expression in gastric neoplasm is inversely correlated to that of miR (zeige MLXIP Proteine)-381.TMEM16A mediates the functional effects of miR (zeige MLXIP Proteine)-381 on migration and invasion in gastric cancer cells.

  3. Positive anoctamin 1 (ANO1) is a promising biomarker to predict the unfavorable outcome for ESCC patients and disease progression of precancerous lesions.

  4. TMEM16A expression was enhanced by 24-h treatment of IL-4 (zeige IL4 Proteine) in human nasal epithelial cells.

  5. findings demonstrate that Ca2 (zeige CA2 Proteine)+ influx via store-operated CRAC channels is essential for CaCC (zeige CLCA1 Proteine) activation, chloride secretion, and sweat production in humans and mice.

  6. TMEM16A activation as a sequential, direct, and Vm-dependent binding.

  7. Ano1(0) without EAVK [Ano1(0)DeltaEAVK] has reduced sensitivity for intracellular calcium, attributable to slower kinetics. Differential expression of EAVK may function as a calcium-sensitive switch in the human stomach.

  8. Gains of ANO1 is associated with oropharyngeal squamous cell carcinoma.

  9. DOG1 is a novel marker for identifying intercellular canaliculi and is a potential immunomarker of myoepithelial cells specific to mammary glands, anogenital mammary-like glands and tumors originating therein.

  10. Increase in TMEM16A activity occurred within minutes of exposure to CLCA1 (zeige CLCA1 Proteine) or after a short treatment with nocodazole, consistent with the hypothesis that CLCA1 (zeige CLCA1 Proteine) stabilizes TMEM16A at the cell surface by preventing its internalization.

Mouse (Murine) Anoctamin 1, Calcium Activated Chloride Channel (ANO1) Interaktionspartner

  1. ANO1 immunoreactivity was observed in the presynaptic terminals of various retinal neurons, including photoreceptors

  2. In this work we demonstrate that increasing the extracellular proton concentration from 10-10 to 10-5.5 m enabled TMEM16A activation. Furthermore, we show that this effect is voltage independent, caused by changes in the apparent open probability of the channel, and due to protonation of extracellular residue E623

  3. The present study shows that ANO1 and CavL play a central role in the generation of slow waves, phasic contractions and tone in the internal anal sphincter and that this pathway can occur in the absence of stretch

  4. findings demonstrate that Ca2 (zeige CA2 Proteine)+ influx via store-operated CRAC channels is essential for CaCC (zeige CLCA1 Proteine) activation, chloride secretion, and sweat production in humans and mice.

  5. We knocked out Ano1 to varying degrees in interstitial cells of Cajal (ICC) of adult mice. Partial knockout of Ano1 shortened the widths of electrical slow waves and Ca(2 (zeige CA2 Proteine)+) transients in myenteric ICC but Ca(2 (zeige CA2 Proteine)+) transient synchronicity was preserved. Near-complete knockout was necessary for transient desynchronization and loss of slow waves, indicating a large functional reserve of Ano1 in ICC.

  6. Phosphorylation levels of P38 (zeige CRK Proteine) and JNK (zeige MAPK8 Proteine) in siRNA-TMEM16A group were lower than that of the Model group. Thus, TMEM16A is one of the critical components of a signal transduction pathway that links renal injury to podocyte apoptosis in DN.

  7. To determine the role of ANO1 in physiological functions.

  8. ANO1/TMEM16A is a significant pathway in pancreatic acinar cells for HCO3 (-) secretion into the lumen.

  9. TMEM16A is a positive regulator of endothelial reactive oxygen species generation via Nox2 (zeige CYBB Proteine)-containing NADPH oxidase (zeige NOX1 Proteine), which induces endothelial dysfunction and hypertension.

  10. Data indicate that anoctamin channel proteins ANO1 and ANO2 (zeige ANO2 Proteine) are expressed in the cerebellum.

ANO1 Protein Überblick

Protein Überblick

Acts as a calcium-activated chloride channel. Required for normal tracheal development (By similarity).

Genbezeichner und Symbole assoziert mit ANO1

  • anoctamin 1 (Ano1)
  • anoctamin 1 (ANO1)
  • anoctamin 1, calcium activated chloride channel (Ano1)
  • DOG1 Protein
  • ORAOV2 Protein
  • TAOS2 Protein
  • Tmem16a Protein

Bezeichner auf Proteinebene für ANO1

anoctamin 1, calcium activated chloride channel , Ca-activated chloride channel Tmem16A , anoctamin-1 , discovered on gastrointestinal stromal tumors protein 1 , oral cancer overexpressed 2 , transmembrane protein 16A (eight membrane-spanning domains) , tumor-amplified and overexpressed sequence 2 , transmembrane protein 16A

GENE ID SPEZIES
100529098 Cavia porcellus
55107 Homo sapiens
423144 Gallus gallus
532126 Bos taurus
101772 Mus musculus
309135 Rattus norvegicus
611698 Canis lupus familiaris
Ausgewählte Anbieter für ANO1 Proteine (ANO1)
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