anti-Anaphase Promoting Complex Subunit 11 (ANAPC11) Antikörper

Probably catalytic subunit of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin- protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Human ANAPC11 ANAPC11 51529 Q9NYG5
Anti-Ratte ANAPC11 ANAPC11 498030  
Anti-Maus ANAPC11 ANAPC11 66156 Q9CPX9
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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, IP, WB Conjugation pathways for ubiquitin and ubiquitin-like modifiers (UBLs). Most modifiers mature by proteolytic processing from inactive precursors (a, amino acid). Arrowheads point to the cleavage sites. Ubiquitin is expressed either as polyubiquitin or as a fusion with ribosomal proteins. Conjugation requires activating (E1) and conjugating (E2) enzymes that form thiolesters (S) with the modifiers. Modification of cullins by RUB involves SCF(SKP1/cullin-1/F-box protein) /CBC(cullin-2/elongin B/elonginC) -like E3 enzymes that are also involved in ubiquitination. In contrast to ubiquitin, the UBLs do not seem to form multi-UBL chains. UCRP(ISG15) resembles two ubiquitin moieties linked headto- tail. Whether HUB1 functions as a modifier is currently unclear. APG12 and URM1 are distinct from the other modifiers because they are unrelated in sequence to ubiquitin. Data contributed by S.Jentsch, see references below. 0.1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$533.50
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Human Maus Unkonjugiert IF, IHC, IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$522.50
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Human Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$474.10
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Human Maus Unkonjugiert IF, WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
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Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p), WB   0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$585.06
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Human Kaninchen Unkonjugiert ELISA, ICC, IF, WB Immunocytochemistry/Immunofluorescence: Apc11 Antibody [NBP1-76260] - Immunofluorescence of APC11 in 3T3 cells with APC11 antibody at 20 ug/mL. Western Blot: Apc11 Antibody [NBP1-76260] - Analysis of APC11 in 3T3 cell tissue lysate with APC11 antibody at (A) 1 and (B) 2 ug/mL. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$485.88
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Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p), WB Anti-ANAPC11 / APC11 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959612 concentration 5 ug/ml. Anti-ANAPC11 / APC11 antibody IHC staining of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959612 concentration 5 ug/ml. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
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Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
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Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: Apc11 Antibody [NBP1-90139] - Staining of human prostate shows moderate nuclear positivity in glandular cells. Western Blot: Apc11 Antibody [NBP1-90139] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY424181) 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
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Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged ANAPC11 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
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Am meisten referenzierte anti-Anaphase Promoting Complex Subunit 11 Antikörper

  1. Human Polyclonal ANAPC11 Primary Antibody für ELISA, IHC - ABIN4281020 : Ohta, Michel, Xiong: Association with cullin partners protects ROC proteins from proteasome-dependent degradation. in Oncogene 2000 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Anaphase Promoting Complex Subunit 11 Interaktionspartner

Human Anaphase Promoting Complex Subunit 11 (ANAPC11) Interaktionspartner

  1. siRNA targeted against Apc11 could hamper entry into G2/M phase.

  2. The authors showed, in vitro, a direct interaction between Orf virus anaphase promoting complex regulator and APC2 and its interference with interactions between APC11 and APC2.

  3. Studies indicate that APC (zeige APC Antikörper)/C(Cdh1 (zeige CDH1 Antikörper)) is required to maintain genomic stability.

  4. APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex.

  5. Inhibition of APC11 function by H(2)O(2) contributes to the delay in cell cycle progression through mitosis that is characteristic of cells subjected to oxidative stress

Anaphase Promoting Complex Subunit 11 (ANAPC11) Antigen-Profil

Protein Überblick

Probably catalytic subunit of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin- protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin- conjugating E2 enzymes, it catalyzes the formation of protein- ubiquitin conjugates that are subsequently degraded by the 26S proteasome. In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition. In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication. APC11 is required to recruit the ubiquitin- conjugating enzyme E2 to the APC/C.

Genbezeichner und Symbole assoziert mit ANAPC11

  • anaphase promoting complex subunit 11 (ANAPC11) Antikörper
  • anaphase promoting complex subunit 11 L homeolog (anapc11.L) Antikörper
  • anaphase promoting complex subunit 11 (anapc11) Antikörper
  • anaphase promoting complex subunit 11 (Anapc11) Antikörper
  • anaphase promoting complex subunit 11 (APC11) Antikörper
  • anaphase-promoting complex subunit Apc11 (apc11) Antikörper
  • anaphase promoting complex subunit 11 (CAALFM_CR10610CA) Antikörper
  • ubiquitin-protein ligase Anaphase Promoting Complex (APC11) Antikörper
  • hypothetical protein (APC11) Antikörper
  • predicted protein (APC11) Antikörper
  • anaphase-promoting complex subunit 11 (LOC9320604) Antikörper
  • anaphase promoting complex subunit 11 (LOC692923) Antikörper
  • APC11 anaphase promoting complex subunit 11 homolog (yeast) (anapc11) Antikörper
  • 1110011I19Rik Antikörper
  • anapc11 Antikörper
  • APC11 Antikörper
  • Apc11p Antikörper
  • DDBDRAFT_0187183 Antikörper
  • DDBDRAFT_0231277 Antikörper
  • DDB_0187183 Antikörper
  • DDB_0231277 Antikörper
  • R75218 Antikörper
  • RGD1561880 Antikörper
  • si:dkey-237i9.4 Antikörper
  • zgc:153671 Antikörper

Bezeichner auf Proteinebene für ANAPC11

APC11 anaphase promoting complex subunit 11 homolog , anaphase promoting complex subunit 11 (yeast APC11 homolog) , anaphase-promoting complex subunit 11 , cyclosome subunit 11 , hepatocellular carcinoma-associated RING finger protein , anaphase promoting complex subunit 11 , anaphase promoting complex subunit 11 homolog , Apc11p , Catalytic core subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition , anaphase-promoting complex subunit Apc11 , potential anaphase-promoting complex subunit Apc11 , ubiquitin-protein ligase Anaphase Promoting Complex , hypothetical protein , anaphase-promoting complex/cyclosome 11 , APC11

GENE ID SPEZIES
51529 Homo sapiens
496247 Xenopus laevis
496610 Xenopus (Silurana) tropicalis
498030 Rattus norvegicus
851554 Saccharomyces cerevisiae S288c
2543187 Schizosaccharomyces pombe 972h-
3639005 Candida albicans SC5314
4852029 Scheffersomyces stipitis CBS 6054
5718640 Chlamydomonas reinhardtii
7203954 Phaeodactylum tricornutum CCAP 1055/1
8248072 Micromonas sp. RCC299
8625855 Dictyostelium discoideum AX4
9320604 Arabidopsis lyrata subsp. lyrata
454972 Pan troglodytes
483370 Canis lupus familiaris
616275 Bos taurus
100173127 Pongo abelii
66156 Mus musculus
692923 Bombyx mori
768140 Danio rerio
100734505 Cavia porcellus
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