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ADPRHL2 encodes a member of the ADP-ribosylglycohydrolase family. Zusätzlich bieten wir Ihnen ADP-Ribosylhydrolase Like 2 Antikörper (37) und und viele weitere Produktgruppen zu diesem Protein an.
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Study results establish ARH3 as a serine mono-ADP-ribosylhydrolase and as an important regulator of the basal and stress-induced ADP-ribosylome.
By screening for the hydrolase that is responsible for the reversal of Ser-ADP ribosilation, the authors identified ARH3/ADPRHL2 as capable of efficiently and specifically removing Ser-ADP ribosilation of histones and other proteins.
ADP-ribosylhydrolase 3 (ARH3), not poly(ADP-ribose) glycohydrolase (PARG) isoforms, is responsible for degradation of mitochondrial matrix-associated poly(ADP-ribose).
ARH3 has poly(ADP-ribose) glycohydrolase activity but is structurally unrelated to poly(ADP-ribose) glycohydrolase
cloning, recombinant production, purification and crystallization of ARH3 consisting of 347 amino-acid residues
The molecular architecture of human ARH3 constitutes the archetype of an all-alpha-helical protein fold and suggests reversibility mechanisms of protein ADP-ribosylation.
poly(ADP-ribose) glycohydrolase ARH3 hydrolyzed O-acetyl-ADP-ribose to produce ADP-ribose in a time- and Mg(2+)-dependent reaction and thus could participate in two signaling pathways
This gene encodes a member of the ADP-ribosylglycohydrolase family. The encoded enzyme catalyzes the removal of ADP-ribose from ADP-ribosylated proteins. This enzyme localizes to the mitochondria, in addition to the nucleus and cytoplasm.
poly(ADP-ribose) glycohydrolase ARH3
, ADP-ribosylhydrolase 3
, [Protein ADP-ribosylarginine] hydrolase-like protein 2
, protein ADP-ribosylarginine hydrolase-like protein 2
, ADP-ribosylhydrolase 2
, ecto ADP-ribosylhydrolase