Arl5, an ARF-like family small GTPase, interacts with Ragulator in an amino acid-regulated manner and both Arl5 and its effector, the Golgi-associated retrograde protein complex (GARP), are required for the AA-stimulated trafficking.
microRNA-202-3p inhibits cell proliferation by targeting ADP-ribosylation factor-like 5A in human colorectal carcinoma.
developmentally regulated ARL5, with its distinctive nuclear/nucleolar localization and interaction with HP1alpha, may play a role(s) in nuclear dynamics and/or signaling cascades during embryonic development
crystal structure
The protein encoded by this gene belongs to the ARF family of GTP-binding proteins. With its distinctive nuclear/nucleolar localization and interaction with HP1alpha, the protein is developmentally regulated and may play a role(s) in nuclear dynamics and/or signaling cascades during embryonic development. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes.
ADP-ribosylation factor-like 5A , ADP-ribosylation factor-like 8 , ADP-ribosylation factor-like protein 5A , ADP-ribosylation factor-like protein 5a , ADP-ribosylation factor-like 5 , ADP-ribosylation factor-like protein 5
GENE ID | SPEZIES |
---|---|
448415 | Xenopus (Silurana) tropicalis |
736445 | Pan troglodytes |
100286429 | Salmo salar |
100343969 | Oryctolagus cuniculus |
100528100 | Ictalurus punctatus |
436611 | Danio rerio |
496255 | Xenopus laevis |
26225 | Homo sapiens |
100683961 | Canis lupus familiaris |
519694 | Bos taurus |
75423 | Mus musculus |
117050 | Rattus norvegicus |
100861140 | Capra hircus |
100302313 | Ovis aries |
176392 | Caenorhabditis elegans |