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ARF5 is a member of the human ADP-ribosylation factor (ARF) gene family.
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GORAB (zeige GORAB ELISA Kits) missense mutation disrupt ARF5 binding in Golgi apparatus in patients, with genetic skin diseases.
BRAG2 acts at clathrin-coated pits to promote integrin internalization by activating Arf5 and suggest a previously unrecognized role for Arf5 in clathrin-mediated endocytosis of specific cargoes.
a novel molecular mechanism of circular dorsal ruffles ring size control through the ARAP1-Arf1/5 pathway.
a crucial role for class II Arf proteins (Arf4 (zeige ARF4 ELISA Kits) and Arf5) in the dengue flavivirus life cycle
The lipid droplets deposition and the cellular triacylglycerol content are significantly increased by siRNA-mediated depletion of Arf5.
somal CAPS2 (zeige CADPS2 ELISA Kits) is associated with the Golgi membrane, and mediates binding and recruitment of the GDP-bound form of ARF4 (zeige ARF4 ELISA Kits) and ARF5 (members of the membrane-trafficking small GTPase (zeige RACGAP1 ELISA Kits) family) to the Golgi membrane
a functional role for CAPS1 (zeige CAPS ELISA Kits) in regulating DCV trafficking in the trans-Golgi network; this activity occurs via protein-protein interaction with ARF4 (zeige ARF4 ELISA Kits)/ARF5 in a GDP-dependent manner.
This gene is a member of the human ADP-ribosylation factor (ARF) gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6). The members of each class share a common gene organization.