anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2) Antikörper

Bezeichnung:
anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 Antikörper (APBA2)
Auf www.antikoerper-online.de finden Sie aktuell 75 Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2) Antikörper von 23 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 Proteine (4) und Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 Kits (1) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 87 Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 Produkte verfügbar.
Synonyme:
D15S1518E, HsT16821, LIN-10, MGC83599, MGC:14091, Mint2, mXllL, X11-BETA, X11-like, X11L, XllL

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Am meisten referenzierte anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 Antikörper

  1. Human Polyclonal APBA2 Primary Antibody für EIA, WB - ABIN950450 : Swistowski, Zhang, Orcholski, Crippen, Vitelli, Kurakin, Bredesen: Novel mediators of amyloid precursor protein signaling. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 (PubMed)
    Zeige alle 3 Referenzen für 950450

Weitere Antikörper gegen Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 Interaktionspartner

Human Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2) Interaktionspartner

  1. Mints are necessary for activity-induced APP (zeige APP Antikörper) and PS1 (zeige PSEN1 Antikörper) trafficking and provide insight into the cellular fate of APP (zeige APP Antikörper) in endocytic pathways essential for Abeta (zeige APP Antikörper) production.

  2. Aberrant MINT2 methylation in body fluids may predict peritoneal micrometastasis for gastric cancer (GC) patients, which is a potential poor prognostic factor in GC.

  3. a significant difference was shown for APBA2 gene expression of peripheral lymphocytes between Chinese Han Tourette syndrome (TS) group and healthy controls idicating the APBA2 gene is a promising peripheral blood biomarker that discriminates between patients with TS and healthy subjects

  4. Amyloid beta A4 precursor protein-binding family A member 2 contains a potent neuronal promoter whose activity may be regulated by DNA methylation (zeige HELLS Antikörper) and glucocorticoid receptor (zeige NR3C1 Antikörper) [alpha], paired box protein 5 (zeige CAPS Antikörper).

  5. The co-occurrence of two nonsynonymous mutations in both affected siblings in a single family, each transmitted from a different unaffected parent, suggest a role for APBA2 mutations in rare individuals with ASD (zeige ARSD Antikörper).

  6. APBA2 were genes activated in early endometrial endometrioid carcinoma (stages I-II).

  7. X11beta-mediated reduction in cerebral Abeta (zeige APP Antikörper) is associated with cognition and long-term potentiation in Alzheimer's disease APPswe transgenic mice.

  8. Interaction of transcriptional coactivators with Mint1 (zeige APBA1 Antikörper) or Mint2 prevents nuclear localization and transactivation of the transduction network mediated by amyloid precursor protein (zeige APP Antikörper).

  9. The APBA2 gene has been found to map to a more telomeric location in chromosome 15q13 than previously found, and is partially duplicated within the broader region located approximately 5 Mb distal to the intact locus.

  10. hXB51 isoforms regulate Abeta (zeige APP Antikörper) generation differently, either enhancing it by modifying the association of X11L with APP (zeige APP Antikörper) or suppressing it in an X11L-independent manner

Mouse (Murine) Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2) Interaktionspartner

  1. Results indicate that both X11 (zeige APBA1 Antikörper) and X11L exert largely in brain neurons, but X11 (zeige APBA1 Antikörper) may also function in peripheral tissues.

  2. X11beta reduces amyloid beta-protein levels and amyloid plaque formation in the brains of transgenic mice

  3. X11L suppresses the amyloidogenic but not amyloidolytic processing of APP (zeige APP Antikörper) in regions of the brain such as the hippocampus, which express significant levels of X11L.

  4. shuttled between the cytoplasm and nucleus, the former more effectively than the latter; leptomycin B (LMB) induced substantial nuclear accumulation of EGFP-X11L

  5. X11s associate primarily with APP (zeige APP Antikörper) molecules that are outside of DRM (zeige GREM1 Antikörper), that the dissociation of APP (zeige APP Antikörper)-X11 (zeige APBA1 Antikörper)/X11L complexes leads to entry of APP (zeige APP Antikörper) into DRM (zeige GREM1 Antikörper), and that cleavage of uncomplexed APP (zeige APP Antikörper) by BACE (zeige BACE Antikörper) within DRM (zeige GREM1 Antikörper)

  6. This study suggested X11L is involved in the development of neuronal circuits that contribute to conflict resolution.

Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2)

  • amyloid beta (A4) precursor protein-binding, family A, member 2 (APBA2) Antikörper
  • amyloid beta (A4) precursor protein-binding, family A, member 2 (apba2) Antikörper
  • amyloid beta (A4) precursor protein-binding, family A, member 2 (Apba2) Antikörper
  • D15S1518E Antikörper
  • HsT16821 Antikörper
  • LIN-10 Antikörper
  • MGC83599 Antikörper
  • MGC:14091 Antikörper
  • Mint2 Antikörper
  • mXllL Antikörper
  • X11-BETA Antikörper
  • X11-like Antikörper
  • X11L Antikörper
  • XllL Antikörper

Bezeichner auf Proteinebene für APBA2

amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like) , amyloid beta (A4) precursor protein-binding, family A, member 2 , amyloid beta A4 precursor protein-binding, family A, member 2 , amyloid beta A4 precursor protein-binding family A member 2 , X11-like protein , adapter protein X11beta , mint-2 , neuron-specific X11L protein , neuronal munc18-1-interacting protein 2 , phosphotyrosine-binding/-interacting domain (PTB)-bearing protein , Mint 2 , neuronal Munc18-1-interacting protein 2 , amyloid beta (A4) precursor protein-binding family A member 2 (X11-like)

GENE ID SPEZIES
100059336 Equus caballus
447055 Xenopus laevis
453697 Pan troglodytes
514762 Bos taurus
321 Homo sapiens
11784 Mus musculus
83610 Rattus norvegicus
415386 Gallus gallus
488700 Canis lupus familiaris
100172037 Pongo abelii
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