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anti-CACNA2D2 (CACNA2D2) Antikörper

Bezeichnung:
anti-Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 2 Antikörper (CACNA2D2)
Auf www.antikoerper-online.de finden Sie aktuell 37 Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 2 (CACNA2D2) Antikörper von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CACNA2D2 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 49 CACNA2D2 Produkte verfügbar.
Synonyme:
a2d2, Cacna2d, du, LUAC11.1, mKIAA0558, td, torpid
Alle Antikörper anzeigen Gen GeneID UniProt
CACNA2D2 9254 Q9NY47
CACNA2D2 56808 Q6PHS9
CACNA2D2 300992 Q8CFG6

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Weitere Synonyme anzeigen

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anti-Human CACNA2D2 Antikörper:

anti-Mouse (Murine) CACNA2D2 Antikörper:

anti-Rat (Rattus) CACNA2D2 Antikörper:

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Am meisten referenzierte anti-CACNA2D2 Antikörper

  1. Human Monoclonal CACNA2D2 Primary Antibody für IF, ELISA - ABIN522733 : Pippucci, Parmeggiani, Palombo, Maresca, Angius, Crisponi, Cucca, Liguori, Valentino, Seri, Carelli: A novel null homozygous mutation confirms CACNA2D2 as a gene mutated in epileptic encephalopathy. in PLoS ONE 2013 (PubMed)

Weitere Antikörper gegen CACNA2D2 Interaktionspartner

Human Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 2 (CACNA2D2) Interaktionspartner

  1. The investigation of single nucleotide polymorphisms in three genes that have a functional impact on the opioid response: OPRM1 (zeige OPRM1 Antikörper), ABCB1 (zeige ABCB1 Antikörper) and the calcium channel complex subunit CACNA2D2, is reported.

  2. CACNA2D2 deletion/methylation is associated with cervical disease progression.

  3. In mice, targeted disruption of Cacna2d2 led to growth retardation, reduced life span, ataxia (zeige USP14 Antikörper), enhanced susceptibility to seizures, and cardiac abnormalities. Cacna2d2 may be involved in hereditary cerebellar ataxias and epileptic disorders in humans.

  4. Although transgenic du(2J)/+ mice have a marked reduction in alpha2delta-2 protein, they show no fall in Purkinje somatic calcium currents or increase in cerebellar tyrosine hydroxylase (zeige TH Antikörper) gene expression.

Mouse (Murine) Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 2 (CACNA2D2) Interaktionspartner

  1. all of the alpha(2)delta subunits studied, alpha(2)delta-1, alpha(2)delta-2, and alpha(2)delta-3 (zeige CACNA2D3 Antikörper), show all of the properties expected of glycosylphosphatidylinositol-anchored proteins, both when heterologously expressed and in native tissues.

  2. We show that both mRNA and protein corresponding to this predicted transcript are expressed in du/du cerebellum and present in Purkinje cells

  3. Cacna2d2 has a role in epilepsy and ataxia (zeige USP14 Antikörper)

  4. In mice, targeted disruption of Cacna2d2 led to growth retardation, reduced life span, ataxia (zeige USP14 Antikörper), enhanced susceptibility to seizures, and cardiac abnormalities. Cacna2d2 may be involved in hereditary cerebellar ataxias and epileptic disorders in humans.

  5. Both alpha2delta-2 and CaV2.1 (zeige CACNA1A Antikörper) are normally associated with cholesterol-rich microdomains, and this influences their functionality.

CACNA2D2 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with CACNA2D2

  • calcium channel, voltage-dependent, alpha 2/delta subunit 2 (CACNA2D2) Antikörper
  • calcium channel, voltage-dependent, alpha 2/delta subunit 2 (Cacna2d2) Antikörper
  • a2d2 Antikörper
  • Cacna2d Antikörper
  • du Antikörper
  • LUAC11.1 Antikörper
  • mKIAA0558 Antikörper
  • td Antikörper
  • torpid Antikörper

Bezeichner auf Proteinebene für CACNA2D2

alpha 2 delta calcium channel subunit , gene 26 , voltage-dependent calcium channel subunit alpha-2/delta-2 , voltage-gated calcium channel subunit alpha-2/delta-2 , ducky , protein ducky , calcium channel, voltage dependent, alpha2/delta subunit 2

GENE ID SPEZIES
9254 Homo sapiens
56808 Mus musculus
300992 Rattus norvegicus
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