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anti-Human Pleiotrophin Antikörper:
anti-Mouse (Murine) Pleiotrophin Antikörper:
anti-Rat (Rattus) Pleiotrophin Antikörper:
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Human Monoclonal Pleiotrophin Primary Antibody für IHC (p), ELISA - ABIN562528
Koutsioumpa, Hatziapostolou, Mikelis, Koolwijk, Papadimitriou: Aprotinin stimulates angiogenesis and human endothelial cell migration through the growth factor pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta. in European journal of pharmacology 2009
Show all 7 Pubmed References
Human Polyclonal Pleiotrophin Primary Antibody für EIA, IHC (p) - ABIN115512
Asari, Kanemitsu, Kurihara: Oral administration of high molecular weight hyaluronan (900 kDa) controls immune system via Toll-like receptor 4 in the intestinal epithelium. in The Journal of biological chemistry 2010
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Human Polyclonal Pleiotrophin Primary Antibody für ELISA, WB - ABIN4346164
Kretschmer, Fairhurst, Hulmes, Popjes, Böhlen, Kovesdi: Genomic organization of the human HBNF gene and characterization of an HBNF variant protein as a splice mutant. in Biochemical and biophysical research communications 1993
zebrafish HBNF was able to enhance extensive neurite outgrowth in zebrafish embryos during embryogenesis
PTN knockdown attenuated the progression of experimental PVR (zeige PVR Antikörper) in vivo. These findings provide new insights into the pathogenesis of PVR (zeige PVR Antikörper).
Annealing helicase HARP closes RPA-stabilized DNA bubbles non-processively.
Neural precursor cell (NPC (zeige NPC1 Antikörper)):glioma cell communication underpins the propensity of glioma to colonize the lateral ventricle subventricular zone (SVZ) through secretion of chemoattractant signals toward which glioma cells home; analyses of SVZ NPC (zeige NPC1 Antikörper)-secreted factors revealed the neurite outgrowth-promoting factor pleiotrophin, with required SPARC (zeige SPARC Antikörper)/SPARCL1 and HSP90B (zeige HSP90AB1 Antikörper) as mediators of this chemoattractant effect.
these data indicate that PTN-PTPRZ (zeige PTPRZ1 Antikörper)-A signaling controls the timing of oligodendrocyte precursor cell differentiation in vivo, in which the CS moiety of PTPRZ (zeige PTPRZ1 Antikörper) receptors maintains them in a monomeric active state until its ligand binding.
PTN could be considered as a potential biomarker for the presence of breast cancer.
this study shows that the expression of PTN is significantly downregulated in keloid fibroblasts compared to normal human fibroblasts
findings link pleiotrophin abundance in gliomas with survival in humans and mice, and show that pleiotrophin promotes glioma progression through increased VEGF deposition and vascular abnormalization.
PTN levels in amniotic fluid were found to be lower in pregnancies complicated by chorioamnionitis than in healthy pregnancies.
Increased Pleiotrophin Concentrations in Papillary Thyroid Cancer
Data show that binding of pleiotrophin (PTN) to neuropilin-1 (NRP-1 (zeige NRP1 Antikörper)) stimulated the internalization and recycling of NRP-1 (zeige NELL1 Antikörper) at the cell surface.
The results of this study suggested that regulation of the PTN signaling pathways may constitute new therapeutic opportunities particularly in those neurological disorders characterized by increased PTN cerebral levels and neuroinflammation.
antagonizes Brd2 (zeige BRD2 Antikörper) promoting cell differentiation associated with the neural tube: spinal cord neurogenesis and neural crest migration
PTN-mediated hematopoietic regeneration occurs in a RAS-dependent manner.
the absence of PTN in vivo is associated with disruption of specific cognitive and affective processes
The results of this study indicated that PTN may be a novel genetic factor of importance in alcohol use disorders.
data suggest that the spinal antinociceptive effects caused by stimulation of alpha2-adrenoceptors are differentially regulated by endogenous expression of PTN
PTN overexpression exerts various effects on sarcolemma ion channel expression/function and resting cytosolic calcium concentrations in soleus and extensor digitorum longus muscles.
Vivarium-housed Wt controls had higher levels of active TGF-beta1 (zeige TGFB1 Antikörper) and IL-2 (zeige IL2 Antikörper) in inguinal lymph nodes relative to PTN-Tg mice.
Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti- apoptotic signaling of PTN and regulation of cell proliferation (By similarity).
heparin-binding neurite-promoting factor
, pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)
, heparin affin regulatory protein
, heparin binding growth factor 8
, heparin-binding brain mitogen
, heparin-binding growth factor 8
, heparin-binding growth-associated molecule
, heparin-binding neurite outgrowth-promoting factor 1
, neurite growth-promoting factor 1
, osteoblast-specific factor 1
, pleiotrophic factor-beta-1
, heparin-binding neutrophic factor
, heparin affin regulatory peptide
, heparin-binding neurite promoting factor
, heparin-binding neurotorphic factor
, osteoblastic cell factor
, Pleiotrophin (Heparine binding factor, Hbnf, in the mouse)
, heparin binding factor