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Pleiotrophin Antikörper (C-Term)

PTN Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6266311
  • Target Alle Pleiotrophin (PTN) Antikörper anzeigen
    Pleiotrophin (PTN)
    Bindungsspezifität
    • 14
    • 9
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 51
    • 28
    • 27
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    Human, Maus, Ratte
    Wirt
    • 68
    • 6
    • 2
    • 2
    Kaninchen
    Klonalität
    • 71
    • 7
    Polyklonal
    Konjugat
    • 35
    • 12
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Pleiotrophin Antikörper ist unkonjugiert
    Applikation
    • 45
    • 26
    • 26
    • 25
    • 21
    • 16
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    Western Blotting (WB), ELISA
    Spezifität
    PTN Antibody detects endogenous levels of total PTN.
    Homologie
    Pig,Bovine,Horse,Rabbit,Dog,Chicken
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human PTN, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product PTN Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    Pleiotrophin (PTN)
    Andere Bezeichnung
    PTN (PTN Produkte)
    Synonyme
    zHBNF antikoerper, zgc:111787 antikoerper, harp antikoerper, hbnf antikoerper, X-PTF antikoerper, hbgf8 antikoerper, negf1 antikoerper, ptn antikoerper, PTN antikoerper, HARP antikoerper, HBGF8 antikoerper, HBNF antikoerper, NEGF1 antikoerper, PTN-A antikoerper, HB-GAM antikoerper, HBBM antikoerper, HBGF-8 antikoerper, OSF-1 antikoerper, HBBN antikoerper, OSF antikoerper, Osf-1 antikoerper, Osf1 antikoerper, Hbnf antikoerper, pleiotrophin antikoerper, pleiotrophin L homeolog antikoerper, ptn antikoerper, PTN antikoerper, ptn.L antikoerper, Ptn antikoerper
    Hintergrund

    Description: Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells (PubMed:1768439, PubMed:1733956). Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation (PubMed:11278720). Binds to cell-surface target proteins via their chondroitin sulfate groups (PubMed:26896299). Down-regulates PTPRZ1 activity (PubMed:16814777).

    Gene: PTN

    Molekulargewicht
    19kDa
    Gen-ID
    5764
    UniProt
    P21246
    Pathways
    RTK Signalweg
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