anti-OGT (OGT) Antikörper

Bezeichnung:
anti-O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) Antikörper (OGT)
Auf www.antikoerper-online.de finden Sie aktuell 110 O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT) Antikörper von 22 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen OGT Proteine (5) und OGT Kits (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 125 OGT Produkte verfügbar.
Synonyme:
1110038P24Rik, 4831420N21Rik, AI115525, BcDNA:GH04245, CG10392, Dmel\\CG10392, fm81g08, HRNT1, l(2)02637, l(2)NC130, O-GLCNAC, ogt, Ogtl, P1201, Sxc, sxc/Ogt, wu:fc12b01, wu:fm81g08

Meistgesuchte Reaktivitäten zu anti-OGT (OGT) Antikörper

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anti-Rat (Rattus) OGT Antikörper:

anti-Human OGT Antikörper:

anti-Mouse (Murine) OGT Antikörper:

Alle verfügbaren anti-OGT Antikörper

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Am meisten referenzierte anti-OGT Antikörper

  1. Cow (Bovine) Monoclonal OGT Primary Antibody für ChIP, DB - ABIN152683 : Dias, Cheung, Hart: O-GlcNAcylation of kinases. in Biochemical and biophysical research communications 2012 (PubMed)
    Zeige alle 5 Referenzen für 152683

  2. Human Polyclonal OGT Primary Antibody für EIA, WB - ABIN453239 : Fujiki, Chikanishi, Hashiba, Ito, Takada, Roeder, Kitagawa, Kato: GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis. in Nature 2009 (PubMed)
    Zeige alle 3 Referenzen für 453239

  3. Human Polyclonal OGT Primary Antibody für IHC (p), WB - ABIN390649 : Taylor, Geisler, Chambers, McClain: Up-regulation of O-GlcNAc transferase with glucose deprivation in HepG2 cells is mediated by decreased hexosamine pathway flux. in The Journal of biological chemistry 2009 (PubMed)
    Zeige alle 3 Referenzen für 390649

  4. Mouse (Murine) Polyclonal OGT Primary Antibody für ELISA, WB - ABIN252910 : Majumdar, Wright, Markowitz, Martinez-Hernandez, Raghow, Solomon: Insulin stimulates and diabetes inhibits O-linked N-acetylglucosamine transferase and O-glycosylation of Sp1. in Diabetes 2004 (PubMed)

  5. Human Polyclonal OGT Primary Antibody für ICC, IF - ABIN442747 : Ise, Goto, Komura, Akaike: Engulfment and clearance of apoptotic cells based on a GlcNAc-binding lectin-like property of surface vimentin. in Glycobiology 2012 (PubMed)

  6. Cow (Bovine) Polyclonal OGT Primary Antibody für IHC, WB - ABIN2783662 : Taylor, Parker, Hazel, Soesanto, Fuller, Yazzie, McClain: Glucose deprivation stimulates O-GlcNAc modification of proteins through up-regulation of O-linked N-acetylglucosaminyltransferase. in The Journal of biological chemistry 2008 (PubMed)

  7. Cow (Bovine) Monoclonal OGT Primary Antibody für ELISA, FACS - ABIN4341246 : Swamy, Pathak, Grzes, Damerow, Sinclair, van Aalten, Cantrell: Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy. in Nature immunology 2016 (PubMed)

Weitere Antikörper gegen OGT Interaktionspartner

Fruit Fly (Drosophila melanogaster) O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT) Interaktionspartner

  1. Here is presented a novel O-GlcNAc transferase (OGT), EOGT (zeige C3orf64 Antikörper), responsible for extracellular O-linked-N-acetylglucosamine acylation.

  2. study found that the super sex combs (sxc)gene encodes O-linked N-acetylglucosamine transferase (Ogt); Polycomb (zeige CBX2 Antikörper) repression appears to be a critical function of Sxc/Ogt in Drosophila and may be mediated by the glycosylation of Polyhomeotic

Zebrafish O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT) Interaktionspartner

  1. Developmental regulation of zOGT transcriptional variants generated by alternative splicing and characterization of their OGT activities of protein O-GlcNAcylation.

  2. Overexpression of Ogt delayed epiboly and caused a severe disorganization of the microtubule and actin based cytoskeleton in the extra-embryonic yolk syncytial layer.

Cow (Bovine) O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT) Interaktionspartner

  1. Hsp90 is involved in the regulation of OGT and O-GlcNAc modification and that Hsp90 inhibitors might be used to modulate O-GlcNAc modification and reverse its adverse effects in human diseases.

Human O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT) Interaktionspartner

  1. Mutations in N-acetylglucosamine (O-GlcNAc) transferase in patients with X-linked intellectual disability

  2. This work uncovers that URI (zeige C19orf2 Antikörper)-regulated OGT confers c-MYC (zeige MYC Antikörper)-dependent survival functions in response to glucose fluctuations.

  3. The results of this study showed that the OGT is essential for sensory neuron survival and target innervation.

  4. The authors show that O-GlcNAcylation of KEAP1 (zeige KEAP1 Antikörper) by OGT at serine 104 is required for the efficient ubiquitination and degradation of NRF2 (zeige GABPA Antikörper).

  5. Data suggest that O-GlcNAc transferase 1 (OGT1) specifically binds to, O-GlcNAcylates, and stabilizes nonspecific lethal protein3 (NSL3 (zeige KANSL3 Antikörper)); stabilization of NSL3 (zeige KANSL3 Antikörper) by OGT1 up-regulates global acetylation levels of histone 4 at Lys-5 (zeige AASDHPPT Antikörper), Lys (zeige LYZ Antikörper)-8, and Lys (zeige LYZ Antikörper)-16.

  6. conclusion, our results demonstrated that miR24 inhibits breast cancer cells invasion by targeting OGT and reducing FOXA1 (zeige FOXA1 Antikörper) stability. These results also indicated that OGT might be a potential target for the diagnosis and therapy of breast cancer metastasis.

  7. Fatty acid synthase (zeige FASN Antikörper) fine-tunes the cell's response to stress and injury by remodeling cellular O-GlcNAcylation

  8. OGT functions in metastatic spread of HPV E6/E7-positive HeLa cells to xenografted lungs through E6/E7 (zeige HCFC1 Antikörper), HCF-1 an (zeige CXCR4 Antikörper)d CXCR4

  9. Reducing endogenous mitochondrial OGT expression leads to alterations in mitochondrial structure and function, including Drp1 (zeige CRMP1 Antikörper)-dependent mitochondrial fragmentation, reduction in mitochondrial membrane potential, and a significant loss of mitochondrial content in the absence of mitochondrial reactive oxygen species.

  10. Thus, a single amino acid substitution in the regulatory domain (the tetratricopeptide repeat domain) of OGT, which catalyzes the O-GlcNAc post-translational modification of nuclear and cytosolic proteins, appears causal for X-linked intellectual disability.

Pig (Porcine) O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT) Interaktionspartner

  1. Data suggest that enzymes in hexosamine biosynthesis pathway and downstream protein O-GlcNAcylation are important for preimplantation development (zeige MTA2 Antikörper); these include Ogt, Gfpt (glutamine (zeige GFPT1 Antikörper)-fructose-6-P aminotransferase), and Oga (O-GlcNAcase (zeige MGEA5 Antikörper)).

Mouse (Murine) O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT) Interaktionspartner

  1. O-GlcNAc modification is essential for cold-induced thermogenesis and mitochondrial biogenesis in brown adipose tissue.

  2. This work uncovers that URI (zeige C19orf2 Antikörper)-regulated OGT confers c-MYC (zeige MYC Antikörper)-dependent survival functions in response to glucose fluctuations.

  3. This study identifies OGT activity as an important regulator of SC functions such as myelin maintenance and axonal support.

  4. cullin 3 (CUL3 (zeige CUL3 Antikörper)), a cullin family E3 ubiquitin ligase (zeige MUL1 Antikörper), down-regulates the expression of the O-GlcNAc transferase (OGT) and inhibits STAT3 (zeige STAT3 Antikörper) O-GlcNAcylation.

  5. OGT functions in metastatic spread of HPV E6/E7-positive tumor cells to the lungs through E6/E7, HCF-1 (zeige HCFC1 Antikörper) and CXCR4 (zeige CXCR4 Antikörper)

  6. Furthermore, both Ogt and Oga (zeige MGEA5 Antikörper) were required for the reversion from primed ESD (zeige ESD Antikörper)-EpiSCs to naive rESCs. These findings indicate that O-GlcNAcylation plays an important role in the survival of primed ESD (zeige ESD Antikörper)-EpiSCs and in their reversion to naive rESCs.

  7. Beyond its well-known role in adding beta-O-GlcNAc to serine and threonine residues of nuclear and cytoplasmic proteins, OGT also acts as a protease in the maturation of the cell cycle regulator (zeige CDKN2A Antikörper), HCF-1 (zeige HCFC1 Antikörper), and serves as an integral member of several protein complexes, many of them linked to gene expression. (Review)

  8. the O-linked N-acetylglucosamine (O-GlcNAc) processing enzymes, O-GlcNAc-transferase (OGT) and O-GlcNAcase (OGA (zeige MGEA5 Antikörper)), interact with the (A)gamma-globin (zeige HBG1 Antikörper) promoter at the -566 GATA repressor (zeige ZBTB32 Antikörper) site

  9. OGT overexpression increased the level of OGA (zeige MGEA5 Antikörper), suggesting a compensatory mechanism for the aberrant O-GlcNAcylation.

  10. O-GlcNAc transferase is at least partially required for maintaining cellular proliferative and migratory capacities of cardiomyocytes

OGT Antigen-Profil

Beschreibung des Gens

This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with OGT

  • O-linked N-acetylglucosamine (GlcNAc) transferase (ogt) Antikörper
  • super sex combs (sxc) Antikörper
  • O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1 (ogt.1) Antikörper
  • O-linked N-acetylglucosamine (GlcNAc) transferase (OGT) Antikörper
  • O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) (OGT) Antikörper
  • O-linked GlcNAc transferase (GL50803_12081) Antikörper
  • O-linked GlcNAc transferase (GL50803_41701) Antikörper
  • o-linked GlcNAc transferase (THAPSDRAFT_264441) Antikörper
  • O-linked GlcNAc transferase (spyA) Antikörper
  • O-linked N-acetylglucosamine (GlcNAc) transferase (Ogt) Antikörper
  • O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) (Ogt) Antikörper
  • 1110038P24Rik Antikörper
  • 4831420N21Rik Antikörper
  • AI115525 Antikörper
  • BcDNA:GH04245 Antikörper
  • CG10392 Antikörper
  • Dmel\\CG10392 Antikörper
  • fm81g08 Antikörper
  • HRNT1 Antikörper
  • l(2)02637 Antikörper
  • l(2)NC130 Antikörper
  • O-GLCNAC Antikörper
  • ogt Antikörper
  • Ogtl Antikörper
  • P1201 Antikörper
  • Sxc Antikörper
  • sxc/Ogt Antikörper
  • wu:fc12b01 Antikörper
  • wu:fm81g08 Antikörper

Bezeichner auf Proteinebene für OGT

O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) , O-linked GlcNAc transferase , UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase , CG10392-PA , CG10392-PB , CG10392-PC , O-glycosyltransferase , O-linked N-acetylglucosamine transferase , lethal (2) NC130 , sxc-PA , sxc-PB , sxc-PC , O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 1 , copy I , ogta , UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit , o-linked GlcNAc transferase , TPR repeat-containing protein , UDP-N-acetylglucosamine:peptide N-acetylglucosaminyltransferase , O linked N-acetylglucosamine transferase , O-GlcNAc transferase subunit p110 , O-linked N-acetylglucosamine transferase 110 kDa subunit , UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase , O-GlcNAc transferase p110 subunit , uridinediphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyl transferase , O linked N-acetylglucosamine transferase like , UDP-N-acetylglucosaminyltransferase

GENE ID SPEZIES
447694 Xenopus laevis
35486 Drosophila melanogaster
337685 Danio rerio
422203 Gallus gallus
532053 Bos taurus
553157 Xenopus (Silurana) tropicalis
698268 Macaca mulatta
5700203 Giardia lamblia ATCC 50803
5700847 Giardia lamblia ATCC 50803
7453152 Thalassiosira pseudonana CCMP1335
8625015 Dictyostelium discoideum AX4
26295 Rattus norvegicus
8473 Homo sapiens
480955 Canis lupus familiaris
664652 Sus scrofa
100354727 Oryctolagus cuniculus
108155 Mus musculus
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