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OGT Produkte

(O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT))
This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2009].

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Ausgewählte OGT Kategorien

OGT Antikörper

High quality antibodies with extensive validation data.

OGT ELISA Kits

Reliable ELISA kits for a wide range of species.

OGT Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene OGT Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p), IP, ICC, FACS
Validierungen
  • (8)
Kat. Nr. ABIN2856718
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (8)
Kat. Nr. ABIN3022708
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Rat
Applikation WB, ELISA, IHC, IF, FACS
Validierungen
  • (6)
Kat. Nr. ABIN190863
Menge 100 μg
Datenblatt Datenblatt

Empfohlene OGT ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958285
Menge 96 tests
Datenblatt Datenblatt

Empfohlene OGT Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1313359
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3094291
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3136462
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren OGT Produkten

Lucena, Carvalho-Cruz, Donadio, Oliveira, de Queiroz, Marinho-Carvalho, Sola-Penna, de Paula, Gondim, McComb, Costello, Whelan, Todeschini, Dias: "Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation." in: The Journal of biological chemistry, Vol. 291, Issue 25, pp. 12917-29, (2016) (PubMed).

Banerjee, Sangwan, McGinn, Chugh, Dudeja, Vickers, Saluja: "Triptolide-induced cell death in pancreatic cancer is mediated by O-GlcNAc modification of transcription factor Sp1." in: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 33927-38, (2013) (PubMed).

Ise, Goto, Komura, Akaike: "Engulfment and clearance of apoptotic cells based on a GlcNAc-binding lectin-like property of surface vimentin." in: Glycobiology, Vol. 22, Issue 6, pp. 788-805, (2012) (PubMed).

Allison, Wamsley, Kumar, Li, Gray, Hart, Jones, Mayo: "Modification of RelA by O-linked N-acetylglucosamine links glucose metabolism to NF-?B acetylation and transcription." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 42, pp. 16888-93, (2012) (PubMed).

Taylor, Parker, Hazel, Soesanto, Fuller, Yazzie, McClain: "Glucose deprivation stimulates O-GlcNAc modification of proteins through up-regulation of O-linked N-acetylglucosaminyltransferase." in: The Journal of biological chemistry, Vol. 283, Issue 10, pp. 6050-7, (2008) (PubMed).

Majumdar, Wright, Markowitz, Martinez-Hernandez, Raghow, Solomon: "Insulin stimulates and diabetes inhibits O-linked N-acetylglucosamine transferase and O-glycosylation of Sp1." in: Diabetes, Vol. 53, Issue 12, pp. 3184-92, (2004) (PubMed).

Synonyme und alternative Namen zu OGT

O-linked N-acetylglucosamine (GlcNAc) transferase L homeolog (ogt.L), super sex combs (sxc), O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1 (ogt.1), O-linked N-acetylglucosamine (GlcNAc) transferase (OGT), O-linked N-acetylglucosamine (GlcNAc) transferase (ogt), O-linked GlcNAc transferase (GL50803_12081), O-linked GlcNAc transferase (GL50803_41701), o-linked GlcNAc transferase (THAPSDRAFT_264441), O-linked GlcNAc transferase (spyA), O-linked N-acetylglucosamine (GlcNAc) transferase (Ogt), O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) (Ogt), 1110038P24Rik, 4831420N21Rik, AI115525, BcDNA:GH04245, CG10392, Dmel\\CG10392, fm81g08, HRNT1, l(2)02637, l(2)NC130, O-GLCNAC, OGT, Ogt, ogt, Ogtl, P1201, SXC, Sxc, sxc/Ogt, wu:fc12b01, wu:fm81g08

Bezeichner auf Proteinebene für OGT

  • O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
  • O-linked GlcNAc transferase
  • UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase
  • CG10392-PA
  • CG10392-PB
  • CG10392-PC
  • O-glycosyltransferase
  • O-linked N-acetylglucosamine transferase
  • lethal (2) NC130
  • sxc-PA
  • sxc-PB
  • sxc-PC
  • O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 1
  • copy I
  • ogta
  • UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
  • o-linked GlcNAc transferase
  • TPR repeat-containing protein
  • UDP-N-acetylglucosamine:peptide N-acetylglucosaminyltransferase
  • O linked N-acetylglucosamine transferase
  • O-GlcNAc transferase subunit p110
  • O-linked N-acetylglucosamine transferase 110 kDa subunit
  • UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase
  • O-GlcNAc transferase p110 subunit
  • uridinediphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyl transferase
  • O linked N-acetylglucosamine transferase like
  • UDP-N-acetylglucosaminyltransferase
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