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anti-Human BCLAF1 Antikörper:
anti-Mouse (Murine) BCLAF1 Antikörper:
anti-Rat (Rattus) BCLAF1 Antikörper:
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Human Polyclonal BCLAF1 Primary Antibody für ICC, IF - ABIN151225
Liu, Lu, Miki, Yoshida: Protein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage. in Molecular and cellular biology 2007
Show all 4 Pubmed References
Human Monoclonal BCLAF1 Primary Antibody für IF, WB - ABIN968645
Kasof, Goyal, White: Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins. in Molecular and cellular biology 1999
SMYD3 (zeige SMYD3 Antikörper) physically interacts with the promoter of BCLAF1 and upregulates its expression by accumulating di- and trimethylation of H3K4 at the BCLAF1 locus. BCLAF1 depletion inhibits SMYD3 (zeige SMYD3 Antikörper)-induced autophagy.
The Bclaf1 can interact with the leucine zipper region of C/EBPbeta (zeige CEBPB Antikörper) and cooperate with C/EBPbeta (zeige CEBPB Antikörper) to upregulate IL-8 (zeige IL8 Antikörper).
both cytoplasmic BCLAF1 expression and nuclear BCLAF1 expression are increased in post-neoadjuvant therapy rectal cancer, and that negative and weak nuclear BCLAF1 expression are independently associated with a poor prognosis
SRSF10 (zeige SRSF10 Antikörper) is a key regulator of BCLAF1 pre-mRNA splicing and the maintenance of oncogenic features in human colon cancer cells
findings showed that FXR1P (zeige FXR1 Antikörper) interacts with BTF in vivo and proved that FXR1P (zeige FXR1 Antikörper) and BTF can co-localize mainly in the cytoplasm around the nucleus
BTF has functions distinct from TRAP150 (zeige THRAP3 Antikörper) in regulating the subcellular distribution of mRNAs in human cells.
BCLAF1 co-localized with gammaH2AX (zeige H2AFX Antikörper) foci in nuclei and stabilized the Ku70 (zeige XRCC6 Antikörper)/DNA-PKcs (zeige PRKDC Antikörper) complex therein, facilitating non-homologous end joining (NHEJ)-based DSB repair in surviving cells.
In the absence of BclAF1 neutralization, viral gene expression and replication are inhibited. These data identify two temporally and mechanistically distinct functions used by human cytomegalovirus to down-regulate a cellular antiviral protein
Sirt1 (zeige SIRT1 Antikörper) negatively regulates T cell activation via H3K56 deacetylation at the promoter region to inhibit transcription of Bclaf1
We replicated the association of BCL2L11 (zeige BCL2L11 Antikörper) and CASP9 (zeige CASP9 Antikörper) with non-Hodgkin's lymphoma risk at the gene and SNP level, and identified novel associations with BCLAF1 and BAG5 (zeige BAG5 Antikörper).
Constitutive expression of the anti-apoptotic molecule Bfl1 (zeige BCL2A1 Antikörper) (A1) in murine vascular Endothelial Cells leads to prolonged allograft survival due to modifying inflammation.
Bclaf1 facilitates the differentiation of early retinal precursors into retinal ganglion cells, amacrine cells, and horizontal cells rather than into cone photoreceptors.
Bclaf1 expression was found to be strongly upregulated during the saccular stage of murine embryonic lung development and was dispensable for thymocyte development.
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
BCL2-associated transcription factor 1
, bcl-2-associated transcription factor 1
, mitochondrial fission regulator 2
, protein FAM54A