TNFRSF1A Proteine (TNFRSF1A)

Bezeichnung:
Tumor Necrosis Factor Receptor Superfamily, Member 1A Proteine (TNFRSF1A)
Auf www.antikoerper-online.de finden Sie aktuell 69 Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Proteine von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TNFRSF1A Antikörper (451) und TNFRSF1A Kits (59) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 604 TNFRSF1A Produkte verfügbar.
Synonyme:
CD120a, FPF, MS5, p55, p55-R, p60, TBP1, TNF-alphaR1, TNF-R, TNF-R-I, TNF-R1, TNF-R55, TNFalpha-R1, TNFAR, Tnfr-2, Tnfr1, TNFR1-d2, TNFR55, TNFR60, TNFR I, TNFRI, TNFRp55, TNFRSF1A, wu:fj65b10, xtnfr1, zgc:85914
alle Proteine anzeigen Gen GeneID UniProt
TNFRSF1A 7132 P19438
TNFRSF1A 21937 P25118
TNFRSF1A 25625 P22934

Weitere Synonyme anzeigen

TNFRSF1A Proteine (TNFRSF1A) nach Spezies

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Am meisten referenzierte TNFRSF1A Proteine

  1. Human TNFRSF1A Protein expressed in Escherichia coli (E. coli) - ABIN1047844 : Gray, Barrett, Chantry, Turner, Feldmann: Cloning of human tumor necrosis factor (TNF) receptor cDNA and expression of recombinant soluble TNF-binding protein. in Proceedings of the National Academy of Sciences of the United States of America 1990 (PubMed)
    Zeige alle 5 Referenzen für 1047844

  2. Human TNFRSF1A Protein expressed in Human Cells - ABIN2003515 : Banner, DArcy, Janes, Gentz, Schoenfeld, Broger, Loetscher, Lesslauer: Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation. in Cell 1993 (PubMed)
    Zeige alle 5 Referenzen für 2003515

  3. Rat (Rattus) TNFRSF1A Protein expressed in Human Cells - ABIN2009259 : Chan, Chun, Zheng, Siegel, Bui, Lenardo: A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling. in Science (New York, N.Y.) 2000 (PubMed)
    Zeige alle 5 Referenzen für 2009259

  4. Mouse (Murine) TNFRSF1A Protein expressed in Human Cells - ABIN2007897 : Lewis, Tartaglia, Lee, Bennett, Rice, Wong, Chen, Goeddel: Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Zeige alle 5 Referenzen für 2007897

  5. Human TNFRSF1A Protein expressed in HEK-293 Cells - ABIN2181839 : Jiang, Woronicz, Liu, Goeddel: Prevention of constitutive TNF receptor 1 signaling by silencer of death domains. in Science (New York, N.Y.) 1999 (PubMed)
    Zeige alle 3 Referenzen für 2181839

  6. Human TNFRSF1A Protein expressed in Escherichia coli (E. coli) - ABIN1098686 : Dunbar, Song, Guo, Wu, Donner: Two-hybrid cloning of a gene encoding TNF receptor-associated protein 2, a protein that interacts with the intracellular domain of the type 1 TNF receptor: identity with subunit 2 of the 26S protease. in Journal of immunology (Baltimore, Md. : 1950) 1997 (PubMed)
    Zeige alle 2 Referenzen für 1098686

Weitere Proteine zu TNFRSF1A Interaktionspartnern

Human Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Interaktionspartner

  1. Since mumps virus SH coimmunoprecipitated with tumor necrosis factor receptor 1 (TNFR1), RIP1 (zeige UQCRFS1 Proteine), and IRAK1 (zeige IRAK1 Proteine), we hypothesize that SH exerts its NF-kappaB (zeige NFKB1 Proteine) activation inhibitory function by interacting with TNFR1, interleukin-1 receptor type 1 (IL-1R1), and TLR3 (zeige TLR3 Proteine) complexes in the plasma membrane of infected cells.

  2. a specific link between the penetrance of the TNFRSF1A mutation and the observed T cell phenotype, is reported.

  3. Collectively, this study provides more insights into RELT (zeige RELT Proteine) expression, RELT (zeige RELT Proteine) family member function, and the mechanism of RELT (zeige RELT Proteine)-induced death.

  4. Burkholderia cenocepacia BcaA binds to tumor necrosis factor receptor 1.

  5. In SOD1(G93A) spinal cords, we verified a strict correlation in the expression of the TNFalpha, TNFR1 and GDNF triad at different stages of disease progression. Yet, ablation of TNFR1 completely abolished GDNF rises in both SOD1(G93A) astrocytes and spinal cords, a condition that accelerated motor neuron degeneration and disease progression

  6. TNFRSF1A variants were identified in 10 tumor necrosis factor (zeige TNF Proteine) receptor-associated periodic syndrome patients from 10 independent families. The T61I variant was found in patients, while the V136M and S321I variants were found in 1 patient each. All the patients were heterozygous for the variants. Among the healthy controls, 7 of 363 individuals were heterozygous for the T61I variant.

  7. Voxel-based morphometry was used to analyse the associations between TNFRSF1A (rs4149576 and rs4149577) and grey matter structure. Highly significant genotypic associations with striatal volume but not the hippocampus were seen. Specifically, for rs4149576, G homozygotes were associated with reduced caudate nucleus volumes relative to A homozygotes and heterozygotes. Reduced caudate volumes were observed in C homozygotes

  8. Circulating TNFR1 and 2 were shown to be associated with cardiovascular disease, independent of age, sex, inflammatory markers, and other cardiovascular disease risk factors, in the chronic kidney disease patients

  9. Infection with C. trachomatis disturbs TNFR1 signalling specifically at the level of receptor internalization.

  10. Data suggest that TRAF2 (TNF receptor-associated factor 2 (zeige TRAF2 Proteine)) negatively regulates (1) TNFR1- (tumor necrosis factor binding protein 1)-induced apoptosis, (2) TNFR2 (zeige TNFRSF1B Proteine)- (tumor necrosis factor (zeige TNF Proteine) receptor type 2)-induced non-canonical NFkappaB (zeige NFKB1 Proteine) signaling, and (3) TNF- (tumor necrosis factor (zeige TNF Proteine))-induced necroptosis. [REVIEW]

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Interaktionspartner

  1. impaired TNF (zeige TNF Proteine)/TNFR2 (zeige TNFRSF1B Proteine) signaling enhances Th2 and Th17 polarization and aggravates allergic airway inflammation.

  2. TNFR2 (zeige TNFRSF1B Proteine) activation exerted beneficial effects on OPA1 expression in an aortic constriction model.

  3. Following activation by transmembrane TNF (zeige TNF Proteine), TNFR2 (zeige TNFRSF1B Proteine) initiates pathways that drive oligodendrocytes into a reparative mode contributing to remyelination following disease

  4. The apoptotic signals through TNFR1 appear critical for the pathogenesis of pulmonary emphysema.

  5. In SOD1(G93A) spinal cords, we verified a strict correlation in the expression of the TNFalpha, TNFR1 and GDNF triad at different stages of disease progression. Yet, ablation of TNFR1 completely abolished GDNF rises in both SOD1(G93A) astrocytes and spinal cords, a condition that accelerated motor neuron degeneration and disease progression

  6. TNFR1 signaling in myeloid-derived cells is a critical mediator of both the detrimental and the protective functions of TNF (zeige TNF Proteine) in T cell-induced hepatitis and bacterial infection, respectively.

  7. TNF (zeige TNF Proteine) plays an inhibitory role in modulating myocardial SDF-1 (zeige CXCL12 Proteine) production and blockade of TNF (zeige TNF Proteine) signaling by ablation of TNFR1 and TNFR2 (zeige TNFRSF1B Proteine) genes increased SDF-1 (zeige CXCL12 Proteine) expression in the heart. These data expand on TNF (zeige TNF Proteine) signaling-initiated mechanisms in myocardium, which may lend a more complete understanding of SDF-1 (zeige CXCL12 Proteine) and TNFR-derived actions in hopes of advancing ischemic heart injury treatments.

  8. Results suggest that elevated TNF (zeige TNF Proteine) in the heart, via TNFR1 and TNFR2 (zeige TNFRSF1B Proteine), restrains cardiomyocyte differentiation of resident cardiac stem cells and may enhance adrenergic activation, both effects that would reduce the effectiveness of endogenous cardiac repair and the response to exogenous stem cell therapy, while promoting adverse cardiac remodeling.

  9. Suggest an atheroprotective role of ADAM17 (zeige ADAM17 Proteine), which might be mediated by cleaving membrane-bound TNFalpha (zeige TNF Proteine) and TNFR2 (zeige TNFRSF1B Proteine), thereby preventing overactivation of endogenous TNFR2 (zeige TNFRSF1B Proteine) signaling in cells of the vasculature.

  10. Using in vivo, time-lapse imaging we show that as centrally-projecting pioneer axons from dorsal root ganglia (DRG) enter the spinal cord, they initiate expression of the cytokine TNFalpha (zeige TNF Proteine). This induction coincides with ensheathment of these axons by associated glia via a TNF (zeige TNF Proteine) receptor 2 (TNFR2 (zeige TNFRSF1B Proteine))-mediated process.

Pig (Porcine) Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Interaktionspartner

  1. Retinal ischemia results in increased expression of TNF-alpha (zeige TNF Proteine) and its receptors (TNF-R1 and TNF-R2 (zeige TNFRSF1B Proteine)).

Cow (Bovine) Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Interaktionspartner

  1. These results suggest that TNF-alpha (zeige TNF Proteine) sources include immune cells, as well as large and small luteal cells, and that TNF-RI and TNF-RII (zeige TNFRSF1B Proteine) are present in the luteal cells of the bovine corpus luteum.

  2. The expression and cellular localization of tumor necrosis factor-alpha (TNF (zeige TNF Proteine)) and its receptors (TNFRI and TNFRII (zeige TNFRSF1B Proteine)) mRNAs and proteins, were determined.

  3. The upregulation of TNFRI mRNA expression by IFNG (zeige IFNG Proteine) suggests that TNF (zeige TNF Proteine) and IFNG (zeige IFNG Proteine) synergistically affect the death of luteal endothelial cells resulting in acute luteolysis

  4. TNF (zeige TNF Proteine) binding induces release of AIP1 (DAB2IP (zeige DAB2IP Proteine)) from TNFR1, resulting in cytoplasmic translocation and concomitant formation of an intracellular signaling complex comprised of TRADD (zeige TRADD Proteine), RIP1 (zeige RALBP1 Proteine), TRAF2 (zeige TRAF2 Proteine), and AIPl.

Zebrafish Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Interaktionspartner

  1. Targeted gene knockdown of TNFRSF1B (zeige TNFRSF1B Proteine) in zebrafish embryos results in the induction of a caspase-8 (zeige CASP8 Proteine), caspase-2 (zeige CASP2 Proteine) and P53 (zeige TP53 Proteine)-dependent apoptotic program in endothelial cells that bypasses caspase-3 (zeige CASP3 Proteine).

TNFRSF1A Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease.

Alternative names and synonyms associated with TNFRSF1A

  • tumor necrosis factor receptor superfamily, member 1A (tnfrsf1a)
  • tumor necrosis factor receptor superfamily, member 1A (TNFRSF1A)
  • tumor necrosis factor receptor superfamily, member 1a (Tnfrsf1a)
  • tumor necrosis factor receptor superfamily, member 1A (Tnfrsf1a)
  • tumor necrosis factor receptor superfamily, member 1a (tnfrsf1a)
  • CD120a Protein
  • FPF Protein
  • MS5 Protein
  • p55 Protein
  • p55-R Protein
  • p60 Protein
  • TBP1 Protein
  • TNF-alphaR1 Protein
  • TNF-R Protein
  • TNF-R-I Protein
  • TNF-R1 Protein
  • TNF-R55 Protein
  • TNFalpha-R1 Protein
  • TNFAR Protein
  • Tnfr-2 Protein
  • Tnfr1 Protein
  • TNFR1-d2 Protein
  • TNFR55 Protein
  • TNFR60 Protein
  • TNFR I Protein
  • TNFRI Protein
  • TNFRp55 Protein
  • TNFRSF1A Protein
  • wu:fj65b10 Protein
  • xtnfr1 Protein
  • zgc:85914 Protein

Bezeichner auf Proteinebene für TNFRSF1A

tumor necrosis factor receptor 1 , tumor necrosis factor receptor p60 , tumor necrosis factor receptor superfamily member 1A , tumor necrosis factor type I , tumor necrosis factor receptor superfamily, member 1A , tumor necrosis factor receptor superfamily member 1A-like , TNF-R1 , TNF-RI , TNFR-I , tumor necrosis factor binding protein 1 , tumor necrosis factor receptor 1A isoform beta , tumor necrosis factor receptor type 1 , tumor necrosis factor-alpha receptor , TNF receptor alpha chain , TNF-alpha-R1 , p60 , tumor necrosis factor receptor type I , p55 , p55 TNF receptor , TNF Receptor 1 (TR1) , TNFR1

GENE ID SPEZIES
100137626 Xenopus laevis
100144930 Xenopus (Silurana) tropicalis
403634 Canis lupus familiaris
466934 Pan troglodytes
493957 Felis catus
722033 Macaca mulatta
100059548 Equus caballus
100135698 Ovis aries
100397418 Callithrix jacchus
7132 Homo sapiens
21937 Mus musculus
25625 Rattus norvegicus
397020 Sus scrofa
282527 Bos taurus
418325 Gallus gallus
100713890 Cavia porcellus
406471 Danio rerio
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