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TNFRSF1A Protein (AA 31-210) (GST tag)

TNFRSF1A Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant 90 % ELISA
Produktnummer ABIN1047844
  • Target Alle TNFRSF1A Proteine anzeigen
    TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 31-210
    Spezies
    • 29
    • 15
    • 5
    • 1
    • 1
    • 1
    Human
    Quelle
    • 16
    • 15
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses TNFRSF1A Protein ist gelabelt mit GST tag.
    Applikation
    ELISA
    Sequenz
    VPHLGDREKR DSVCPQGKYI HPQNNSICCT KCHKGTYLYN DCPGPGQDTD CRECESGSFT ASENHLRHCL SCSKCRKEMG QVEISSCTVD RDTVCGCRKN QYRHYWSENL FQCFNCSLCL NGTVHLSCQE KQNTVCTCHA GFFLRENECV SCSNCKKSLE CTKLCLPQIE NVKGTEDSGT
    Produktmerkmale
    Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
    Reinheit
    90 %
    Top Product
    Discover our top product TNFRSF1A Protein
  • Kommentare

    The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Konzentration
    0.2-2 mg/mL
    Buffer
    Tris-based buffer, 50 % glycerol
    Handhabung
    Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
  • Himmler, Maurer-Fogy, Krönke, Scheurich, Pfizenmaier, Lantz, Olsson, Hauptmann, Stratowa, Adolf: "Molecular cloning and expression of human and rat tumor necrosis factor receptor chain (p60) and its soluble derivative, tumor necrosis factor-binding protein." in: DNA and cell biology, Vol. 9, Issue 10, pp. 705-15, (1991) (PubMed).

    Gray, Barrett, Chantry, Turner, Feldmann: "Cloning of human tumor necrosis factor (TNF) receptor cDNA and expression of recombinant soluble TNF-binding protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 19, pp. 7380-4, (1990) (PubMed).

    Schall, Lewis, Koller, Lee, Rice, Wong, Gatanaga, Granger, Lentz, Raab: "Molecular cloning and expression of a receptor for human tumor necrosis factor." in: Cell, Vol. 61, Issue 2, pp. 361-70, (1990) (PubMed).

    Loetscher, Pan, Lahm, Gentz, Brockhaus, Tabuchi, Lesslauer: "Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor." in: Cell, Vol. 61, Issue 2, pp. 351-9, (1990) (PubMed).

    Nophar, Kemper, Brakebusch, Englemann, Zwang, Aderka, Holtmann, Wallach et al.: "Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form ..." in: The EMBO journal, Vol. 9, Issue 10, pp. 3269-78, (1990) (PubMed).

  • Target
    TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
    Andere Bezeichnung
    Tumor necrosis factor receptor superfamily member 1A protein (TNFRSF1A Produkte)
    Synonyme
    CD120a Protein, FPF Protein, MS5 Protein, TBP1 Protein, TNF-R Protein, TNF-R-I Protein, TNF-R55 Protein, TNFAR Protein, TNFR1 Protein, TNFR1-d2 Protein, TNFR55 Protein, TNFR60 Protein, p55 Protein, p55-R Protein, p60 Protein, TNF-R1 Protein, TNF-alphaR1 Protein, TNFRI Protein, TNFRp55 Protein, TNFalpha-R1 Protein, Tnfr-2 Protein, Tnfr1 Protein, fpf Protein, tbp1 Protein, p55-r Protein, tnf-r Protein, tnfar Protein, tnfr1 Protein, cd120a Protein, tnfr55 Protein, tnfr60 Protein, xtnfr1 Protein, wu:fj65b10 Protein, zgc:85914 Protein, TNFR I Protein, TNFRSF1A Protein, TNFA Protein, cTNF Protein, TNF receptor superfamily member 1A Protein, tumor necrosis factor receptor superfamily, member 1a Protein, TNF receptor superfamily member 1A S homeolog Protein, tumor necrosis factor Protein, TNFRSF1A Protein, Tnfrsf1a Protein, tnfrsf1a.S Protein, tnfrsf1a Protein, TNF Protein
    Hintergrund
    Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
    Molekulargewicht
    47.6 kD
    UniProt
    P19438
    Pathways
    NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Hepatitis C, Ubiquitin Proteasome Pathway
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