anti-GNAQ (GNAQ) Antikörper

Bezeichnung:
anti-Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide Antikörper (GNAQ)
Auf www.antikoerper-online.de finden Sie aktuell 85 Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) Antikörper von 19 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen GNAQ Proteine (13) und GNAQ Kits (1) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 108 GNAQ Produkte verfügbar.
Synonyme:
1110005L02Rik, 6230401I02Rik, AA408290, AW060788, CMC1, Dsk1, Dsk10, g-alpha-q, Galphaq, gaq, Gnaq, gnaqb, Gq, GqI, si:ch73-270f14.2, SWS

Meistgesuchte Reaktivitäten zu anti-GNAQ (GNAQ) Antikörper

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anti-Human GNAQ Antikörper:

anti-Rat (Rattus) GNAQ Antikörper:

anti-Mouse (Murine) GNAQ Antikörper:

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Am meisten referenzierte anti-GNAQ Antikörper

  1. Chicken Monoclonal GNAQ Primary Antibody für IF, WB - ABIN968914 : Dutt, Kjoller, Giel, Hall, Toksoz: Activated Galphaq family members induce Rho GTPase activation and Rho-dependent actin filament assembly. in FEBS letters 2002 (PubMed)
    Zeige alle 3 Referenzen für 968914

  2. Human Polyclonal GNAQ Primary Antibody für WB - ABIN658100 : Klenke, Tan, Hahn, Mann, Hauner, Manthey, Peters, Siffert, Frey: A functional GNAQ promoter haplotype is associated with altered Gq expression and with insulin resistance and obesity in women with polycystic ovary syndrome. in Pharmacogenetics and genomics 2010 (PubMed)
    Zeige alle 2 Referenzen für 658100

  3. Human Polyclonal GNAQ Primary Antibody für ELISA, WB - ABIN4315225 : Ngai, Inngjerdingen, Berge, Taskén: Interplay between the heterotrimeric G-protein subunits Galphaq and Galphai2 sets the threshold for chemotaxis and TCR activation. in BMC immunology 2009 (PubMed)

  4. Cow (Bovine) Polyclonal GNAQ Primary Antibody für WB - ABIN2785811 : Arnaud-Lopez, Usala, Ceresini, Mitchell, Pilia, Piras, Sestu, Maschio, Busonero, Albai, Dei, Lai, Mulas, Crisponi, Tanaka, Bandinelli, Guralnik, Loi, Balaci, Sole, Prinzis, Mariotti, Shuldiner, Cao, Schlessinger, Uda, Abecasis, Nagaraja, Sanna, Naitza: Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function. in American journal of human genetics 2008 (PubMed)

Weitere Antikörper gegen GNAQ Interaktionspartner

Human Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) Interaktionspartner

  1. The findings of the work indicate a role for Galphaq and/or Galpha14 and in CCR2a/CCR2b (zeige CCR2 Antikörper)-stimulated Rho A (zeige RHOA Antikörper) GTPase (zeige RACGAP1 Antikörper)-mediated serum response factor activation.

  2. GNAQ/11 mutant clones make up a fraction of the cells in choroidal nevi. Nevus cells are furthermore characterised by heterogeneous YAP (zeige YAP1 Antikörper) expression. Combined GNAQ/11 and YAP (zeige YAP1 Antikörper) may constitute a putative precursor tumour pathway with an activated oncogene (zeige RAB1A Antikörper) (GNAQ/11) and downstream effector (YAP (zeige YAP1 Antikörper)).

  3. RasGRP3 (zeige RASGRP3 Antikörper) mediates ERK MAPK (zeige MAPK1 Antikörper) pathway activation in GNAQ mutant uveal melanoma.

  4. Galphaq regulates the development of rheumatoid arthritis by modulating Th1 (zeige TH1L Antikörper) differentiation

  5. The GC/GC (zeige GC Antikörper) genotype of the TT(-695/-694)GC polymorphism is associated with increased Gq protein expression, augmented angiotensin II receptor type 1 (zeige AGTR1 Antikörper)-related vasoconstriction, and increased myocardial injury after coronary artery bypass grafting.

  6. we find iris melanomas to be related genetically to choroidal and ciliary body melanomas, frequently harboring GNAQ, GNA11 (zeige GNA11 Antikörper), and EIF1AX (zeige EIF1AX Antikörper) mutations.

  7. Data suggest that allosteric communication between heterodimeric AT1R and PTGFR is mediated through GNAQ and may also involve proximal phospholipase C but not distal protein kinase C signaling partners; PTGFR activation has negligible effects on AT1R-based conformational biosensors. (AT1R = angiotensin II receptor, type 1; PTGFR = prostaglandin F2alpha receptor; GNAQ = GTP-binding protein G[q] subunit alpha)

  8. GNAQ and GNA11 mutations occur frequently in mucosal melanoma and may be a prognostic factor for MM. Our data implicate that GNAQ/11 may be potential targets for targeted therapy of mucosal melanoma.

  9. Results found that GNAQ was highly expressed in gastric cancer (GC) patient samples and suggest that GNAQ plays a critical role in regulating GC cell growth and survival via canonical oncogenic signaling pathways including MAPK (zeige MAPK1 Antikörper) and p53 (zeige TP53 Antikörper).

  10. These findings suggest that Galphaq/11 participates in the sensing/transducing of shear stress independently of GPCR activation in ECs.

Pig (Porcine) Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) Interaktionspartner

  1. The Galphas (zeige GNAS Antikörper) and Galphaq peptides adopt different orientations in beta2-AR and V1AR (zeige AVPR1A Antikörper), respectively. The beta2-AR/Galphas (zeige GNAS Antikörper) peptide interface is dominated by electrostatic interactions, whereas the V1AR (zeige AVPR1A Antikörper)/Galphaq peptide interactions are predominantly hydrophobic.

  2. The phylogenetic trees reveal that porcine Gnaq, is evolutionarily close to the human homolog.

Cow (Bovine) Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) Interaktionspartner

  1. atomic structure of GRK2 (zeige ADRBK1 Antikörper) in complex with Galphaq and Gbetagamma, in which the activated Galpha (zeige SUCLG1 Antikörper) subunit of Gq is fully dissociated from Gbetagamma and dramatically reoriented from its position in the inactive Galphabetagamma heterotrimer [g alphaq]

Mouse (Murine) Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) Interaktionspartner

  1. Galphaq regulates the development of rheumatoid arthritis by modulating Th1 (zeige HAND1 Antikörper) differentiation

  2. Fluid shear stress acts on the Galphaq-ERK5 (zeige MAPK7 Antikörper) signaling pathway to upregulate Cyclin B1 (zeige CCNB1 Antikörper) and CDK1 (zeige CDK1 Antikörper) expression, thereby resulting in MC3T3-E1 cell proliferation.

  3. activation of the Gq-membrane-associated estrogen receptors rapidly stimulates hypothalamic paraventricular nucleus CRH (zeige CRH Antikörper) neurons by suppressing the M-current and potentiating glutamatergic neurotransmission

  4. cell-penetrating peptides should effectively inhibit active Galphaq in cells and that these and genetically encoded sequences may find application as molecular probes, drug leads, and biosensors to monitor the spatiotemporal activation of Galphaq in cells.

  5. The Galphas (zeige GNAS Antikörper) and Galphaq peptides adopt different orientations in beta2-AR and V1AR (zeige AVPR1A Antikörper), respectively. The beta2-AR/Galphas (zeige GNAS Antikörper) peptide interface is dominated by electrostatic interactions, whereas the V1AR (zeige AVPR1A Antikörper)/Galphaq peptide interactions are predominantly hydrophobic.

  6. the results have identified 138 and 150 ovarian genes that are up-regulated or down-regulated, respectively, at the end of gestation in a Galphaq/11-dependent fashion.

  7. The betaARKrgs peptide, but not endogenous GRK2 (zeige ADRBK1 Antikörper), interacted with Galpha(q) and interfered with signaling through this G protein. These data support the development of GRK2 (zeige ADRBK1 Antikörper)-based therapeutic approaches to prevent hypertrophy and heart failure.

  8. Galphaq/Galpha11 signaling pathways play a pivotal role in gene activity patterns during cardiac remodeling.

  9. Developmental AHR activation by pollutants, and other exogenous ligands, increases the likelihood that Gnaq knockout mice will develop autoimmune diseases later in life.

  10. demonstrate that the ability of an MC4R (zeige MC4R Antikörper) agonist delivered to PVN to inhibit food intake is lost in mice lacking G(q/11)alpha in the paraventricular nucleus of the hypothalamus but not in animals deficient for G(s)alpha

GNAQ Antigen-Profil

Beschreibung des Gens

This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.

Alternative names and synonyms associated with GNAQ

  • guanine nucleotide binding protein (G protein), q polypeptide (gnaq) Antikörper
  • guanine nucleotide binding protein (G protein), q polypeptide (GNAQ) Antikörper
  • guanine nucleotide binding protein (G protein), q polypeptide (Gnaq) Antikörper
  • guanine nucleotide binding protein (G protein), q polypeptide (gnaq-b) Antikörper
  • guanine nucleotide binding protein, alpha q polypeptide (Gnaq) Antikörper
  • 1110005L02Rik Antikörper
  • 6230401I02Rik Antikörper
  • AA408290 Antikörper
  • AW060788 Antikörper
  • CMC1 Antikörper
  • Dsk1 Antikörper
  • Dsk10 Antikörper
  • g-alpha-q Antikörper
  • Galphaq Antikörper
  • gaq Antikörper
  • Gnaq Antikörper
  • gnaqb Antikörper
  • Gq Antikörper
  • GqI Antikörper
  • si:ch73-270f14.2 Antikörper
  • SWS Antikörper

Bezeichner auf Proteinebene für GNAQ

Galpha q , gnaqa , guanine nucleotide-binding protein G(q) subunit alpha , guanine nucleotide-binding protein alpha-q , G alpha q , guanine nucleotide binding protein alpha q subunit , guanine nucleotide binding protein, alpha q polypeptide , guanine nucleotide regulatory protein G alpha q , heterotrimeric guanine nucleotide-binding protein alpha q subunit , guanine nucleotide-binding protein G(q) alpha subunit

GENE ID SPEZIES
570108 Danio rerio
2776 Homo sapiens
403928 Canis lupus familiaris
81666 Rattus norvegicus
427262 Gallus gallus
654405 Sus scrofa
536654 Bos taurus
399261 Xenopus laevis
14682 Mus musculus
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