anti-NK2 Homeobox 1 (NKX2-1) Antikörper

anti-NK2 Homeobox 1 Antikörper (NKX2-1)
Auf finden Sie aktuell 205 NK2 Homeobox 1 (NKX2-1) Antikörper von 22 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen NK2 Homeobox 1 Kits (26) und NK2 Homeobox 1 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 246 NK2 Homeobox 1 Produkte verfügbar.
5730442A20Rik, AV026640, BCH, BHC, cPGES, LOC100227803, NK-2, NKX2-1, Nkx2.1, NKX2A, p23, Ptges, sid3177, T/EBP, Tebp, Titf1, titf1-A, Ttf-1, TTF1, Xnkx-2.1
Alle Antikörper anzeigen Gen GeneID UniProt
NKX2-1 7080 P43699
NKX2-1 21869 P50220
NKX2-1 25628  

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Meistgesuchte Reaktivitäten zu anti-NK2 Homeobox 1 (NKX2-1) Antikörper

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anti-Rat (Rattus) Antikörper:

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Am meisten referenzierte anti-NK2 Homeobox 1 Antikörper

  1. Human Monoclonal NKX2-1 Primary Antibody für FACS - ABIN2666281 : Di Palma, DAndrea, Liguori, Liguoro, de Cristofaro, Del Prete, Pappalardo, Mascia, Zannini: TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation. in Experimental cell research 2008 (PubMed)
    Zeige alle 6 Referenzen für 2666281

  2. Human Monoclonal NKX2-1 Primary Antibody für FACS, IHC (p) - ABIN1688762 : Vyberg, Nielsen: Proficiency testing in immunohistochemistry-experiences from Nordic Immunohistochemical Quality Control (NordiQC). in Virchows Archiv : an international journal of pathology 2016 (PubMed)
    Zeige alle 5 Referenzen für 1688762

  3. Human Polyclonal NKX2-1 Primary Antibody für IHC, ELISA - ABIN1532418 : Freeman, Yamamoto: Disassembly of transcriptional regulatory complexes by molecular chaperones. in Science (New York, N.Y.) 2002 (PubMed)

Weitere Antikörper gegen NK2 Homeobox 1 Interaktionspartner

Human NK2 Homeobox 1 (NKX2-1) Interaktionspartner

  1. Immunohistochemical detection of thyroid transcription factor 1, Napsin A (zeige NAPSA Antikörper), and P40 (zeige IL9 Antikörper) fragment of TP63 (zeige TP63 Antikörper) can be used in the subclassification of non-small cell lung carcinomas.

  2. The rate of TTF-1-positive circulating tumor cells was strongly correlated with TNM (zeige ODZ1 Antikörper) staging, vascular infiltration, lymphatic metastasis, and the levels of CA125 (zeige MUC16 Antikörper), CA15.3, and HE4 (zeige WFDC2 Antikörper) in endometrial carcinoma.

  3. Study postulated that both TTF-1 and PAX-8 (zeige PAX8 Antikörper) when co-expressed and have anti-proliferative and anti-tumorigenic properties up to a threshold expression level and beyond that, are able to induce pro-tumorigenic effects in thyroid carcinomas.

  4. Results suggest that the thyroid transcription factor 1 expression was independently associated with progression-free survival and overall survival in patients with advanced-stage non-squamous non-small cell lung cancer treated with pemetrexed-based chemotherapy.

  5. These findings describe recurrent NKX2-1 mutations in invasive mucinous adenocarcinomas of the lung and support NKX2-1 as a lineage-specific tumor suppressor gene in lung carcinogenesis.

  6. Report TTF1 expression is common in combined Merkel cell carcinoma.

  7. Preoperative serum miR (zeige MLXIP Antikörper)-365 and TTF-1 mRNA levels may be effective indicators of tumor aggressiveness in human NSCLC. miR (zeige MLXIP Antikörper)-365 and its target gene TTF-1 appear to be synergistic risk factors for the reduction in overall survival of patients with NSCLC.

  8. In adenocarcinomas from extrahepatic biliary tract, there was no correlation between TTF-1 expression and the clinicopathological characteristics.

  9. Suggest TTF-1 is a reliable marker in non-small cell lung carcinoma and can be used in differential diagnosis.

  10. EGFR (zeige EGFR Antikörper) knockdown led to upregulation of NKX2-1, suggesting a negative feedback loop. combined knockdown of NKX2-1 and EGFR (zeige EGFR Antikörper) in NCI-H1819 lung cancer cells reduced cell proliferation more than knockdown of either alone.

Mouse (Murine) NK2 Homeobox 1 (NKX2-1) Interaktionspartner

  1. NKX2-1 binding at distal regulatory elements led to a repressed epigenetic state and transcriptional repression in the ventricular zone. Conversely, NKX2-1 is required to establish a permissive chromatin state and transcriptional activation in the sub-ventricular and mantle zones.

  2. Skin differentiation is impaired, and both apoptosis and cell proliferation are augmented in the absence of p23 (zeige CDK5R1 Antikörper); the consequences are a severe thinning of the stratum corneum and reduced numbers of hair follicles. Since the phenotype of p23 (zeige CDK5R1 Antikörper)-null embryos is strikingly similar to that of embryos lacking the glucocorticoid receptor (zeige NR3C1 Antikörper), a paradigmatic Hsp90 (zeige HSP90 Antikörper)-p23 (zeige CDK5R1 Antikörper) client protein, we investigated glucocorticoid signaling.

  3. Study shows that within the NANCI-Nkx2.1 duplex, NANCI plays an essential role in regulating tissue identity by acting as a transcriptional rheostat to buffer Nkx2.1 expression. During lung development and in adult lung homeostasis, NANCI acts in cis (zeige CISH Antikörper) to positively regulate Nkx2.1, and, in turn, Nkx2.1 directly inhibits NANCI expression.

  4. Results identified two proteins P23 (zeige CDK5R1 Antikörper) and HCLS1 (zeige HCLS1 Antikörper), which were not known as RNA-binding proteins, exhibiting RNA-binding activity.

  5. data indicate that TTF-1 interacts with PPFP to inhibit the pro-adipogenic response to pioglitazone, and that the ability of pioglitazone to decrease TTF-1 expression contributes to its pro-adipogenic action.

  6. Identify regulatory link between Nkx2-1, miR (zeige MLXIP Antikörper)-200c, and the transcription factors Nfib (zeige NFIB Antikörper) and Myb (zeige MYB Antikörper), adding new players to the regulatory mechanisms driven by Nkx2-1 in lung epithelial cells that may have implications in lung development and tumorigenesis.

  7. A population of neural stem cells in the ventral region of the adult ventricular-subventricular zone expresses the transcription factor Nkx2.1 and is derived from Nkx2.1-expressing (Nkx2.1+) embryonic precursors.

  8. We conclude that a dedicated subset of VMHVL neurons marked by ERalpha (zeige ESR1 Antikörper), NKX2-1, and Tac1 (zeige TAC1 Antikörper) regulates estrogen-dependent fluctuations in physical activity and constitutes one of several neuroendocrine modules that drive sex-specific responses.

  9. Prototypic GPe (zeige GYPE Antikörper) neurons derive from the medial ganglionic eminence of the embryonic subpallium and express the transcription factor Nkx2-1. These neurons fire at high rates during alert rest, and encode movements through heterogeneous firing rate changes.

  10. Molecular characterization of disseminated tumor cells indicates that downregulation of the transcription factor Nkx2-1 precedes lung adenocarcinoma dissemination.

NK2 Homeobox 1 (NKX2-1) Antigen-Profil

Beschreibung des Gens

This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TFF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.

Alternative names and synonyms associated with NK2 Homeobox 1 (NKX2-1)

  • thyroid transcription factor 1 (titf1-A) Antikörper
  • NK2 homeobox 1 (NKX2-1) Antikörper
  • thyroid transcription factor 1 (LOC100227803) Antikörper
  • NK2 homeobox 1 (Nkx2-1) Antikörper
  • prostaglandin E synthase 3 (cytosolic) (Ptges3) Antikörper
  • thyroid transcription factor 1-like (LOC100154384) Antikörper
  • 5730442A20Rik Antikörper
  • AV026640 Antikörper
  • BCH Antikörper
  • BHC Antikörper
  • cPGES Antikörper
  • LOC100227803 Antikörper
  • NK-2 Antikörper
  • NKX2-1 Antikörper
  • Nkx2.1 Antikörper
  • NKX2A Antikörper
  • p23 Antikörper
  • Ptges Antikörper
  • sid3177 Antikörper
  • T/EBP Antikörper
  • Tebp Antikörper
  • Titf1 Antikörper
  • titf1-A Antikörper
  • Ttf-1 Antikörper
  • TTF1 Antikörper
  • Xnkx-2.1 Antikörper

Bezeichner auf Proteinebene für NKX2-1

thyroid transcription factor 1 , NK2 homeobox 1 , NK-2 homolog A , homeobox protein NK-2 homolog A , homeobox protein Nkx-2.1 , thyroid nuclear factor 1 , thyroid-specific enhancer-binding protein , tinman , TTF-1 , thyroid transcription factor 1 TTF-1 NK-2 , thyroid transcription factor-1 , homeodomain protein NKx2.1 , cytosolic prostaglandin E2 synthase , hsp90 co-chaperone , p23 cochaperone , progesterone receptor complex p23 , prostaglandin E synthase 3 , sid 3177 , telomerase binding protein, p23 , telomerase-binding protein p23

373626 Xenopus laevis
452867 Pan troglodytes
100227803 Taeniopygia guttata
7080 Homo sapiens
21869 Mus musculus
25628 Rattus norvegicus
403940 Canis lupus familiaris
395322 Gallus gallus
56351 Mus musculus
100154384 Sus scrofa
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