NKX2-1 Antikörper

Produktnummer ABIN7101514

Produktdetails anti-NKX2-1 Antikörper

Target: NKX2-1 (NK2 Homeobox 1 (NKX2-1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser NKX2-1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human TTF1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NKX2-1

Target: NKX2-1 (NK2 Homeobox 1 (NKX2-1))

Andere Bezeichnung: NKX2-1 (NKX2-1 Produkte)

Synonyme: BCH antikoerper, BHC antikoerper, NK-2 antikoerper, NKX2.1 antikoerper, NKX2A antikoerper, TEBP antikoerper, TITF1 antikoerper, TTF-1 antikoerper, TTF1 antikoerper, titf1-A antikoerper, Xnkx-2.1 antikoerper, NKX2-1 antikoerper, LOC100227803 antikoerper, AV026640 antikoerper, Nkx2.1 antikoerper, T/EBP antikoerper, Titf1 antikoerper, Ttf-1 antikoerper, nk2.1a antikoerper, nkx2.1 antikoerper, nkx2.4a antikoerper, titf1 antikoerper, titf1a antikoerper, NK2 homeobox 1 antikoerper, NK2 homeobox 1 L homeolog antikoerper, NK2 homeobox 4b antikoerper, NKX2-1 antikoerper, nkx2-1.L antikoerper, Nkx2-1 antikoerper, nkx2.4b antikoerper

Hintergrund: This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014],BCH, BHC, NK-2, NKX2.1, NKX2A, NMTC1, T/EBP, TEBP, TITF1, TTF-1, TTF1,Epigenetics & Nuclear Signaling,Transcription Factors,NKX2-1

Molekulargewicht: 39 kDa

Gen-ID: 7080

UniProt: P43699

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour