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Navigieren Sie durch unsere anti-MS4A2 (MS4A2) Antikörper

Full name:
anti-Membrane-Spanning 4-Domains, Subfamily A, Member 2 (Fc Fragment of IgE, High Affinity I, Receptor For, beta Polypeptide) Antikörper (MS4A2)
Auf www.antikoerper-online.de finden Sie aktuell 24 Membrane-Spanning 4-Domains, Subfamily A, Member 2 (Fc Fragment of IgE, High Affinity I, Receptor For, beta Polypeptide) (MS4A2) Antikörper von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MS4A2 Proteine (4) und MS4A2 Kits (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 34 MS4A2 Produkte verfügbar.
Synonyme:
APY, ATOPY, Fce1b, Fcer1b, fcERI, FCIGA, FcRB, Fcrbeta, IGEL, IGER, IGHER, Ms4a1

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anti-Human MS4A2 Antikörper:

anti-Mouse (Murine) MS4A2 Antikörper:

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Weitere Antikörper gegen MS4A2 Interaktionspartner

Human Membrane-Spanning 4-Domains, Subfamily A, Member 2 (Fc Fragment of IgE, High Affinity I, Receptor For, beta Polypeptide) (MS4A2) Interaktionspartner

  1. in patients with allergic rhinitis without asthma, the FCER1B rs569108 and rs512555 polymorphisms are associated with increased risk of developing allergic rhinitis and with lower IgE levels.

  2. study found a difference in the frequencies of genotypes of FcvarepsilonRIbeta subunit int 2 (zeige FGF3 Antikörper) in allergic rhinitis patients and controls. The FcvarepsilonRIbeta subunit int 2 (zeige FGF3 Antikörper) gene polymorphism was found to be associated with allergic rhinitis in the Polish cohort

  3. MS4A2 (zeige MS4A1 Antikörper) was differentially expressed between Fibromyalgia patients and healthy controls.

  4. FcepsilonRIbeta -109C/T and IFN-gamma (zeige IFNG Antikörper) 874T/A polymorphisms may be influencing factors for asthma in the Asian population

  5. The results explain how initial membrane interactions of clustered IgE-Fcepsilon RI complexes lead to downstream cellular responses.

  6. Data indicated that the MS4A2 (zeige MS4A1 Antikörper) gene E237G variant may be a risk factor for developing atopic asthma and the promoter -109T allele is a potential risk factor of asthma in Asians.

  7. Cytoplasmic FcepsilonRIbeta, which is not co-localized with FcepsilonRIalpha, may function as a negative regulator, as it can capture important signalling molecules such as Lyn (zeige LYN Antikörper).

  8. t-FcepsilonRIbeta mediates Ca2 (zeige CA2 Antikörper)+ -dependent microtubule formation, which promotes degranulation and cytokine release.

  9. The interaction between Lyn (zeige LYN Antikörper) and FcepsilonRIbeta is indispensable for FcepsilonRI (zeige FCER1G Antikörper)-mediated human mast cell activation.

  10. Demethylation of specific regulatory elements within the FCER1G (zeige FCER1G Antikörper) locus contributes to FcepsilonRI (zeige FCER1G Antikörper) overexpression on monocytes from patients with atopic dermatitis.

Mouse (Murine) Membrane-Spanning 4-Domains, Subfamily A, Member 2 (Fc Fragment of IgE, High Affinity I, Receptor For, beta Polypeptide) (MS4A2) Interaktionspartner

  1. Analysis of the conformation and thermal stability of the high-affinity IgE Fc receptor beta chain polymorphic proteins has been presented.

  2. chemotaxis toward antigen is controlled in mast cells by a cross-talk among FcepsilonRI (zeige FCER1A Antikörper), tetraspanin CD9 (zeige CD9 Antikörper), transmembrane adaptor proteins NTAL (zeige LAT2 Antikörper) and LAT (zeige LAT Antikörper), and cytoskeleton-regulatory proteins of the ERM (zeige ETV5 Antikörper) family

  3. Findings indicate that SLP-76 (zeige LCP2 Antikörper) is an essential signaling component for basophil activation downstream of both FcepsilonRI (zeige FCER1A Antikörper) and the IL-3 (zeige Il3 Antikörper) receptor.

  4. FcRbeta is a critical element in mast cell synergistic degranulation response through FcepsilonRI (zeige FCER1A Antikörper) & adenosine receptors. PI3K-signaling through FcRbeta-ITAM is a crucial participant in augmentation of FcepsilonRI (zeige FCER1A Antikörper)-mediated degranulation by adenosine.

  5. inhibition of FcepsilonRI (zeige FCER1A Antikörper)-dependent mast cell activation can suppress allergic contact dermatitis

  6. Gene expression profiling after stimulation via high-affinity Fcepsilon receptor I (FcepsilonRI (zeige FCER1A Antikörper)), showed the transcriptional levels of several CC chemokines were markedly increased.

  7. FcepsilonRIbeta functions to both selectively amplify (degranulation and leukotriene secretion) and dampen (lymphokine (zeige IL2 Antikörper)) mast cell effector responses

  8. IgE receptors are expressed on sensory neurons in mice. Immunostaining revealed that the high affinity IgE receptor FcepsilonRI (zeige FCER1A Antikörper) was expressed in cultured dorsal root ganglion cells.

  9. FcepsilonRI (zeige FCER1A Antikörper) beta-chain regulates calcium uptake in mast cells via the immunoreceptor tyrosine-based activation motif.

  10. IgE signaling suppresses FcepsilonRIbeta expression.

MS4A2 Antigen-Profil

Beschreibung des Gens

The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of membrane-spanning 4A gene family members. Alternative splicing results in multiple transcript variants encoding distinct proteins. Additional transcript variants have been described but require experimental validation.

Alternative names and synonyms associated with MS4A2

  • membrane-spanning 4-domains, subfamily A, member 2 (MS4A2) Antikörper
  • membrane-spanning 4-domains, subfamily A, member 2 (Ms4a2) Antikörper
  • APY Antikörper
  • ATOPY Antikörper
  • Fce1b Antikörper
  • Fcer1b Antikörper
  • fcERI Antikörper
  • FCIGA Antikörper
  • FcRB Antikörper
  • Fcrbeta Antikörper
  • IGEL Antikörper
  • IGER Antikörper
  • IGHER Antikörper
  • Ms4a1 Antikörper

Bezeichner auf Proteinebene für MS4A2

Fc fragment of IgE, high affinity I, receptor for; beta polypeptide , High affinity immunoglobulin epsilon receptor beta-subunit (FcERI) (IgE Fc receptor, beta-subunit) (Fc epsilon receptor I beta-chain) , high affinity IgE receptor beta subunit , high affinity immunoglobulin epsilon receptor subunit beta , igE Fc receptor subunit beta , immunoglobulin E receptor, high affinity, beta polypeptide , Fc receptor, IgE, high affinity I, beta polypeptide , fc epsilon receptor I beta-chain , membrane-spanning 4-domains, subfamily A, member 1 , IgE Fc receptor subunit beta , Membrane-spanning 4-domains subfamily A member 1 , Membrane-spanning 4-domains, subfamily A, member 1 , beta polypeptide) , fcERI , membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for , membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)

GENE ID SPEZIES
2206 Homo sapiens
14126 Mus musculus
25316 Rattus norvegicus
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