MS4A2 Antikörper (AA 1-59) (Biotin)

Produktnummer ABIN7155185

Produktdetails anti-MS4A2 Antikörper (Biotin)

Target: MS4A2 (Membrane-Spanning 4-Domains, Subfamily A, Member 2 (Fc Fragment of IgE, High Affinity I, Receptor For, beta Polypeptide) (MS4A2))

Bindungsspezifität: AA 1-59

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MS4A2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human High affinity immunoglobulin epsilon receptor subunit beta protein (1-59AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MS4A2

Target: MS4A2 (Membrane-Spanning 4-Domains, Subfamily A, Member 2 (Fc Fragment of IgE, High Affinity I, Receptor For, beta Polypeptide) (MS4A2))

Andere Bezeichnung: MS4A2 (MS4A2 Produkte)

Synonyme: APY antikoerper, ATOPY antikoerper, FCER1B antikoerper, FCERI antikoerper, IGEL antikoerper, IGER antikoerper, IGHER antikoerper, MS4A1 antikoerper, FcRB antikoerper, Fce1b antikoerper, Fcer1b antikoerper, Fcrbeta antikoerper, Ms4a1 antikoerper, fcERI antikoerper, FCIGA antikoerper, membrane spanning 4-domains A2 antikoerper, membrane-spanning 4-domains, subfamily A, member 2 antikoerper, MS4A2 antikoerper, Ms4a2 antikoerper

Hintergrund:

Background: High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy.

Aliases: APY antibody, ATOPY antibody, Fc epsilon receptor I beta-chain antibody, Fc IgE receptor beta chain antibody, FCER1B antibody, FCERB_HUMAN antibody, FcERI antibody, High affinity immunoglobulin epsilon receptor subunit beta antibody, IgE Fc receptor subunit beta antibody, IGEL antibody, IGHER antibody, Membrane-spanning 4-domains subfamily A member 2 antibody, MS4A1 antibody, Ms4a2 antibody

UniProt: Q01362

Pathways: Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process