MS4A2 Antikörper (AA 51-150) (Biotin)

Produktnummer ABIN1701640

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MS4A2 in WB, ELISA, IHC (fro) und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für MS4A2 Antikörper (AA 51-150) (Biotin) (ABIN1701640)

Target: MS4A2 (Membrane-Spanning 4-Domains, Subfamily A, Member 2 (Fc Fragment of IgE, High Affinity I, Receptor For, beta Polypeptide) (MS4A2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MS4A2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MS4A2 Antikörper (Biotin)

Bindungsspezifität: AA 51-150

Kreuzreaktivität: Human, Maus

Homologie: Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat MS4A2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu MS4A2

Target: MS4A2 (Membrane-Spanning 4-Domains, Subfamily A, Member 2 (Fc Fragment of IgE, High Affinity I, Receptor For, beta Polypeptide) (MS4A2))

Andere Bezeichnung: MS4A2

Hintergrund:

Synonyms: FCIGA, Ms4a1, Fcer1b, High affinity immunoglobulin epsilon receptor subunit beta, FcERI, Fc epsilon receptor I beta-chain, IgE Fc receptor subunit beta, Membrane-spanning 4-domains subfamily A member 2, Ms4a2, Fce1b

Background: High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy.

Gen-ID: 25316

UniProt: P13386

Pathways: Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process