anti-TNFSF10 (TNFSF10) Antikörper

Bezeichnung:
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 Antikörper (TNFSF10)
Auf www.antikoerper-online.de finden Sie aktuell 371 Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) Antikörper von 34 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TNFSF10 Proteine (73) und TNFSF10 Kits (48) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 511 TNFSF10 Produkte verfügbar.
Synonyme:
A330042I21Rik, AI448571, APO-2L, APO2L, CD253, Ly81, TL2, Trail, trail1, xtrail1
Alle Antikörper anzeigen Gen GeneID UniProt
TNFSF10 8743 P50591
TNFSF10 22035 P50592
TNFSF10 246775  

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-TNFSF10 (TNFSF10) Antikörper

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anti-Human TNFSF10 Antikörper:

anti-Mouse (Murine) TNFSF10 Antikörper:

anti-Rat (Rattus) TNFSF10 Antikörper:

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Am meisten referenzierte anti-TNFSF10 Antikörper

  1. Human Monoclonal TNFSF10 Primary Antibody für IHC (p), WB - ABIN252480 : Müller, Raftery, Kather, Giese, Schönrich: Frontline: Induction of apoptosis and modulation of c-FLIPL and p53 in immature dendritic cells infected with herpes simplex virus. in European journal of immunology 2004 (PubMed)
    Zeige alle 7 Referenzen für 252480

  2. Human Monoclonal TNFSF10 Primary Antibody für WB - ABIN967538 : Mariani, Matiba, Armandola, Krammer: Interleukin 1 beta-converting enzyme related proteases/caspases are involved in TRAIL-induced apoptosis of myeloma and leukemia cells. in The Journal of cell biology 1997 (PubMed)
    Zeige alle 6 Referenzen für 967538

  3. Human Polyclonal TNFSF10 Primary Antibody für ELISA, IHC (p) - ABIN1996723 : Song, Jin: TRAIL (CD253), a new member of the TNF superfamily. in Journal of biological regulators and homeostatic agents 2005 (PubMed)
    Zeige alle 2 Referenzen für 1996723

  4. Human Polyclonal TNFSF10 Primary Antibody für IF (p), IHC (p) - ABIN673494 : Fang, Zhang, Qi, Fan, Luo, Liu, Tan: Evodiamine induces G2/M arrest and apoptosis via mitochondrial and endoplasmic reticulum pathways in H446 and H1688 human small-cell lung cancer cells. in PLoS ONE 2014 (PubMed)
    Zeige alle 2 Referenzen für 673494

  5. Dog (Canine) Polyclonal TNFSF10 Primary Antibody für WB - ABIN2792132 : Wu, Tsai, Lin, Chou, Chen, Yang, Hsu, Hsu: Helicobacter pylori enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in human gastric epithelial cells. in World journal of gastroenterology : WJG 2004 (PubMed)
    Zeige alle 2 Referenzen für 2792132

  6. Human Polyclonal TNFSF10 Primary Antibody für WB - ABIN151524 : Herzer, Carbow, Sydor, Sowa, Biesterfeld, Hofmann, Galle, Gerken, Canbay: Deficiency of the promyelocytic leukemia protein fosters hepatitis C-associated hepatocarcinogenesis in mice. in PLoS ONE 2012 (PubMed)

  7. Human Polyclonal TNFSF10 Primary Antibody für IF, ELISA - ABIN1533756 : Wiley, Schooley, Smolak, Din, Huang, Nicholl, Sutherland, Smith, Rauch, Smith: Identification and characterization of a new member of the TNF family that induces apoptosis. in Immunity 1996 (PubMed)

  8. Human Monoclonal TNFSF10 Primary Antibody für FACS - ABIN4897836 : Kalb, Glaser, Stary, Koszik, Stingl: TRAIL(+) human plasmacytoid dendritic cells kill tumor cells in vitro: mechanisms of imiquimod- and IFN-?-mediated antitumor reactivity. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)

  9. Human Monoclonal TNFSF10 Primary Antibody für FACS - ABIN1106154 : Bremer, Samplonius, Peipp, van Genne, Kroesen, Fey, Gramatzki, de Leij, Helfrich: Target cell-restricted apoptosis induction of acute leukemic T cells by a recombinant tumor necrosis factor-related apoptosis-inducing ligand fusion protein with specificity for human CD7. in Cancer research 2005 (PubMed)

Weitere Antikörper gegen TNFSF10 Interaktionspartner

Xenopus laevis Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) Interaktionspartner

  1. xTRAIL1 can cause apoptosis, probably mediated through xDR-Ms, in larval red blood cells, but may not kill adult RBCs, presumably owing to PKC (zeige PKC Antikörper) activation, as part of the mechanism for RBC (zeige CACNA1C Antikörper) switching

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) Interaktionspartner

  1. Caspase-8 can serve in two distinct roles in response to TRAIL receptor engagement, as a scaffold for assembly of a Caspase-8-FADD-RIPK1 "FADDosome" complex, leading to NFkappaB-dependent inflammation, or as a protease that promotes apoptosis.

  2. Endogenous TRAIL/TRAIL-R-mediated CCL2 (zeige CCL2 Antikörper) secretion promotes accumulation of tumor-supportive immune cells in the cancer microenvironment.

  3. Fn14 (zeige TNFRSF12A Antikörper).TRAIL can be converted into a highly effective TRAIL oligomer upon binding to TWEAK (zeige TNFSF12 Antikörper) which induces lymphoblast apoptosis.

  4. BAY61-3606 sensitizes colon cancer cells to TRAIL-induced apoptosis by up-regulating DR4 (zeige HLADRB4 Antikörper) expression in p53 (zeige TP53 Antikörper)-dependent manner and inhibiting NF-kappaB (zeige NFKB1 Antikörper) activity.

  5. High-order TRAIL oligomer formation in TRAIL-coated lipid nanoparticles enhances DR5 (zeige TNFRSF10B Antikörper) cross-linking and increases antitumour effect against colon cancer cells and xenograft tumors.

  6. results suggest that miR (zeige MLXIP Antikörper)-223 increases the sensitivity of TNBCSCs to TRAIL-induced apoptosis by targeting HAX-1 (zeige HAX1 Antikörper)

  7. The results suggested that miR (zeige MLXIP Antikörper)-138 regulates the interferon (zeige IFNA Antikörper)-stimulated gene 15 expression by directly targeting the 3' untranslated region of interferon (zeige IFNA Antikörper)-stimulated gene 15 and modulates the sensitivity to TRAIL-induced apoptosis.

  8. these results demonstrate that high HOTAIR levels increase the resistance of pancreatic cancer cells to TRAIL-induced apoptosis via epigenetic regulation of DR5 (zeige TNFRSF10B Antikörper) expression.

  9. miR (zeige MLXIP Antikörper)-661 overexpression sensitized tumors to TRAIL or STS (zeige STS Antikörper) induced apoptosis in a xenograft mouse model, and these effects were attenuated by co-expression of CYC1 (zeige CYC1 Antikörper).

  10. sorafenib overcomes TRAIL resistance in renal cell carcinoma (zeige MOK Antikörper) by a mechanism that does not rely on Mcl-1 (zeige MCL1 Antikörper) down-regulation but involves ROS (zeige ROS1 Antikörper) accumulation and increased activation of caspase-8 (zeige CASP8 Antikörper)

Pig (Porcine) Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) Interaktionspartner

  1. Data suggest forkhead box protein O1 (FoxO1 (zeige FOXO1 Antikörper)) involvement in the regulation of TNF-related apoptosis-inducing ligand TRAIL and Fas ligand FasL (zeige FASL Antikörper) expression during follicular atresia.

  2. The chromosomal location of the porcine TNFSF10 gene was determined by FISH of a specific BAC clone to metaphase chromosomes The chromosomal location of the porcine TNFSF10 gene was determined by FISH of a specific BAC clone to metaphase chromosomes.

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) Interaktionspartner

  1. Tnfsf10 expression is increased in eosinophilic esophagitis. Tnfsf10(-/-) mice were largely protected from esophageal fibrosis and eosinophilic inflammation.

  2. Diabetes significantly increased OPG (zeige TNFSF11 Antikörper) and the OPG (zeige TNFSF11 Antikörper)/TRAIL ratio expression in the aorta, while dyslipidemia was the major determinant of the changes observed in the heart, where it significantly increased OPG (zeige TNFSF11 Antikörper) and reduced TRAIL expression, thus increasing cardiac OPG (zeige TNFSF11 Antikörper)/TRAIL ratio.

  3. TRAIL can promote angiogenesis following hindlimb ischemia in vivo via NOX4 (zeige NOX4 Antikörper)/eNOS (zeige NOS3 Antikörper)/nitric oxide signaling.

  4. Study reports that loss of the Opg (zeige TNFSF11 Antikörper) gene results in deterioration of abdominal aortic aneurysms (AAA (zeige AAAS Antikörper)), possibly through involvement of TRAIL in smooth muscle actin (SMA (zeige SMN1 Antikörper))-positive cells and myofibroblasts.

  5. PARP1 (zeige PARP1 Antikörper) acts as a prominent upstream regulator of high mobility group box 1 (zeige HMGB1 Antikörper)-mediated autophagy and maintains a homeostatic balance between apoptosis and autophagy, which provides new insight into the mechanism of TNFSF10 resistance

  6. Data suggest that Socs3 (suppressor of cytokine signaling 3 (zeige SOCS3 Antikörper)) plays critical negative role in regulation of Trail expression in endoplasmic reticulum stress in macrophages via Jun N-terminal kinase (zeige MAPK8 Antikörper)/AP-1 (zeige JUN Antikörper) transcription factor signaling.

  7. These findings indicate that acute fasting enhances TRAIL-mediated liver natural killer cell activity against neoplastic cells through upregulation of heat shock protein 70 (zeige HSP70 Antikörper).

  8. These results demonstrated that TRAIL plays a deleterious role in acute kidney injury pathogenesis induced by scald (zeige RDH11 Antikörper) burns

  9. TRAIL-deficiency in ApoE (zeige APOE Antikörper)(-/-) mice exacerbates nephropathy and insulin (zeige INS Antikörper) resistance

  10. Tumor necrosis factor (zeige TNF Antikörper)-related apoptosis-inducing ligand translates neonatal respiratory infection into chronic lung disease.

TNFSF10 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TNFSF10

  • tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10) Antikörper
  • TNF-related apoptosis inducing ligand-like (TRAIL-LIKE) Antikörper
  • tumor necrosis factor (ligand) superfamily, member 10 (tnfsf10) Antikörper
  • tumor necrosis factor (ligand) superfamily, member 10 (Tnfsf10) Antikörper
  • A330042I21Rik Antikörper
  • AI448571 Antikörper
  • APO-2L Antikörper
  • APO2L Antikörper
  • CD253 Antikörper
  • Ly81 Antikörper
  • TL2 Antikörper
  • Trail Antikörper
  • trail1 Antikörper
  • xtrail1 Antikörper

Bezeichner auf Proteinebene für TNFSF10

tumor necrosis factor ligand superfamily member 10 , TNF-related apoptosis inducing ligand , TNF-related apoptosis inducing ligand-like protein , Tnf-alpha related apoptosis inducing ligand , TNF-related apoptosis-inducing ligand 1 , tumor necrosis factor related apoptosis inducing ligand 1 , Apo-2 ligand , TNF-related apoptosis inducing ligand TRAIL , chemokine tumor necrosis factor ligand superfamily member 10 , tumor necrosis factor (ligand) family, member 10 , tumor necrosis factor apoptosis-inducing ligand splice variant delta , tumor necrosis factor-related apoptosis-inducing ligand , TNF-related apoptosis-inducing ligand , TRAIL/APO2L

GENE ID SPEZIES
378894 Gallus gallus
395283 Gallus gallus
100174789 Felis catus
100316914 Xenopus laevis
8743 Homo sapiens
100174780 Canis lupus familiaris
406191 Sus scrofa
22035 Mus musculus
246775 Rattus norvegicus
Ausgewählte Anbieter für anti-TNFSF10 (TNFSF10) Antikörper
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