TRAIL Antikörper
Kurzübersicht für TRAIL Antikörper (ABIN783967)
Target
Alle TRAIL (TNFSF10) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Spezifität
- Recognizes TRAIL.
-
Kreuzreaktivität (Details)
- Species reactivity (tested):Mouse.
-
Aufreinigung
- Affinity Chromatography employing an immobilized Murine TRAIL matrix
-
Immunogen
- Highly pure recombinant Murine TRAIL.
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Rekonstitution
- Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
-
Buffer
- PBS, pH 7.2 without preservatives
-
Konservierungsmittel
- Without preservative
-
Handhabung
- Avoid repeated freezing and thawing.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store the lyophilized antibody at -20 °C. Following reconstitution it is stable for two weeks at 2-8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.
-
Haltbarkeit
- 6 months
-
-
- TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
-
Andere Bezeichnung
- CD253 / TRAIL
-
Hintergrund
- TRAIL is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic Death domain which activates the cell's apoptotic machinery.Synonyms: APO2L, Apo-2 ligand, Apo-2L, TNF-related apoptosis-inducing ligand, TNFSF10, Tumor necrosis factor ligand superfamily member 10
-
Gen-ID
- 10850
-
NCBI Accession
- NP_033451
-
Pathways
- Apoptose, Positive Regulation of Endopeptidase Activity
Target
-