anti-TNFRSF12A (TNFRSF12A) Antikörper

anti-Tumor Necrosis Factor Receptor Superfamily, Member 12A Antikörper (TNFRSF12A)
Auf finden Sie aktuell 104 Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) Antikörper von 23 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TNFRSF12A Proteine (26) und TNFRSF12A Kits (18) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 150 TNFRSF12A Produkte verfügbar.
AI255180, C87282, CD266, Fn14, HPIP, TWEAK-R, TweakR
Alle Antikörper anzeigen Gen GeneID UniProt
TNFRSF12A 51330 Q9NP84
TNFRSF12A 27279 Q9CR75
TNFRSF12A 302965  

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Meistgesuchte Reaktivitäten zu anti-TNFRSF12A (TNFRSF12A) Antikörper

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anti-Human TNFRSF12A Antikörper:

anti-Mouse (Murine) TNFRSF12A Antikörper:

anti-Rat (Rattus) TNFRSF12A Antikörper:

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Am meisten referenzierte anti-TNFRSF12A Antikörper

  1. Human Monoclonal TNFRSF12A Primary Antibody für FACS - ABIN2663248 : Lynch, Wang, Lund, Chen, Leal, Wiley: TWEAK induces angiogenesis and proliferation of endothelial cells. in The Journal of biological chemistry 1999 (PubMed)
    Zeige alle 7 Referenzen für 2663248

  2. Human Monoclonal TNFRSF12A Primary Antibody für FACS, CyTOF - ABIN2661016 : Nakayama, Ishidoh, Kojima, Harada, Kominami, Okumura, Yagita: Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Zeige alle 7 Referenzen für 2661016

  3. Human Monoclonal TNFRSF12A Primary Antibody für FACS - ABIN2663247 : Feng, Guo, Factor, Thorgeirsson, Bell, Testa, Peifley, Winkles: The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas. in The American journal of pathology 2000 (PubMed)
    Zeige alle 6 Referenzen für 2663247

  4. Human Polyclonal TNFRSF12A Primary Antibody für WB - ABIN252585 : Chorianopoulos, Heger, Lutz, Frank, Bea, Katus, Frey: FGF-inducible 14-kDa protein (Fn14) is regulated via the RhoA/ROCK kinase pathway in cardiomyocytes and mediates nuclear factor-kappaB activation by TWEAK. in Basic research in cardiology 2010 (PubMed)

Weitere Antikörper gegen TNFRSF12A Interaktionspartner

Human Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) Interaktionspartner

  1. TWEAK (zeige TNFSF12 Antikörper) upregulated the expression of Fn14.

  2. Fn14.TRAIL can be converted into a highly effective TRAIL oligomer upon binding to TWEAK (zeige TNFSF12 Antikörper) which induces lymphoblast apoptosis.

  3. Data show that aurintricarboxylic acid (ATA) targets the TNF-related WEAK inducer of apoptosis (TWEAK (zeige TNFSF12 Antikörper))-fibroblast growth factor-inducible 14 (zeige DDX3X Antikörper) (Fn14) signaling axis, which could potentially be developed as a new therapeutic agent for treatment of glioblastoma (GBM) patients.

  4. TNFRSF12A was knocked down in the SMMC7721 cell line through siRNA. This demonstrated that cells exhibited reduced reproductive and metastatic capacity ex vivo.

  5. In this review article, we summarize studies indicating that (i) Fn14 gene expression is low in normal brain tissue but is upregulated in advanced brain cancers and, in particular, in GB tumors ; TWEAK (zeige TNFSF12 Antikörper): Fn14 engagement as well as Fn14 overexpression can stimulate glioma cell migration, invasion and resistance to chemotherapeutic agents in vitro.

  6. Fn14 is a receptor of mitogen TWEAK (zeige TNFSF12 Antikörper) (tumor necrosis factor (zeige TNF Antikörper)-like weak inducer of apoptosis), expressed on the membranes of HPCs and promoting their proliferation.

  7. EGFR (zeige EGFR Antikörper) Del 19 may promote Fn14 and JAK1 (zeige JAK1 Antikörper)/STAT1 (zeige STAT1 Antikörper) expression in NSCLC.

  8. TWEAK (zeige TNFSF12 Antikörper)/Fn14 activation induces keratinocyte proliferation under psoriatic inflammation

  9. The results demonstrated that vitreous fluid from patients with PDR had higher levels of TWEAK and Fn14 than that from T2DM patients without PDR, thus suggesting an important regulatory role of TWEAK/Fn14 signaling in the pathogenesis of PDR.

  10. Results indicate that FN14 and GRP94 (zeige HSP90B1 Antikörper) are prediction/prognosis markers which open up new possibilities for preventing/treating brain metastasis in breast cancer patients.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) Interaktionspartner

  1. TWEAK (zeige TNFSF12 Antikörper)/Fn14 interactions play an important role in the pathogenesis of neuropsychiatric lupus by increasing the accumulation of inflammatory cells in the choroid plexus, disrupting blood brain barrier integrity, and increasing neuronal damage

  2. TWEAK (zeige TNFSF12 Antikörper)/Fn14 signaling is strongly implicated in the pathogenesis of the cutaneous manifestations in the MRL/lpr (zeige FAS Antikörper) model of spontaneous lupus in mice.

  3. In SOD1 (zeige SOD1 Antikörper) and Neurotomized mice the results of this studysuggest LC3 (zeige MAP1LC3A Antikörper), Fn14, Bcl3 (zeige BCL3 Antikörper) and Gadd45a (zeige GADD45A Antikörper) as candidate genes involved in the maintenance of the severe atrophic state.

  4. Fn14 mediates wound-healing responses that are necessary to survive acute liver injury during alcohol exposure.

  5. Overexpression of Dnmt3a (zeige DNMT3A Antikörper) inhibits the gene expression of Fn14 and attenuates skeletal muscle atrophy upon denervation. Denervation also causes the activation of ERK1/2 (zeige MAPK1/3 Antikörper), JNK1 (zeige MAPK8 Antikörper)/2, and ERK5 (zeige MAPK7 Antikörper) MAPKs and AP1 (zeige JUN Antikörper) and SP1 (zeige SP1 Antikörper).

  6. TWEAK (zeige TNFSF12 Antikörper)-FN14 signaling is necessary for the healthy adult liver to regenerate normally after acute partial hepatectomy.

  7. The levels of TWEAK receptor Fn14 are increased in skeletal muscle during aging. Deletion of Fn14 attenuates age-associated skeletal muscle fiber atrophy.

  8. this study showed that the apoptosis signal-regulating kinase 1 (ASK1 (zeige MAP3K5 Antikörper))-JNK1 (zeige MAPK8 Antikörper)/2 pathway, which was activated by large magnitude mechanical stretch induced expression of Fn14 gene in osteoblasts.

  9. a model in which constitutive down-regulation of Fn14 facilitates dynamic regulation of Fn14 protein levels and prevents spontaneous or inappropriate receptor signaling.

  10. study demonstrates that TWEAK (zeige TNFSF12 Antikörper) induces muscle atrophy through repressing the levels of PGC-1alpha (zeige PPARGC1A Antikörper)

TNFRSF12A Antigen-Profil

Beschreibung des Gens

Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.

Alternative names and synonyms associated with TNFRSF12A

  • tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A) Antikörper
  • tumor necrosis factor receptor superfamily, member 12a (Tnfrsf12a) Antikörper
  • AI255180 Antikörper
  • C87282 Antikörper
  • CD266 Antikörper
  • Fn14 Antikörper
  • HPIP Antikörper
  • TWEAK-R Antikörper
  • TweakR Antikörper

Bezeichner auf Proteinebene für TNFRSF12A

FGF-inducible 14 , fibroblast growth factor-inducible immediate-early response protein 14 , tumor necrosis factor receptor superfamily member 12A , tweak-receptor , type I transmembrane protein Fn14 , fibroblast growth factor regulated protein 2 , fibroblast growth factor-regulated protein 2 , fibroblast growth factor-inducible 14

51330 Homo sapiens
27279 Mus musculus
610734 Canis lupus familiaris
100217390 Sus scrofa
302965 Rattus norvegicus
Ausgewählte Anbieter für anti-TNFRSF12A (TNFRSF12A) Antikörper
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