anti-Human PARP1 Antikörper für Chromatin Immunoprecipitation

Recommended PARP1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Poly (ADP-Ribose) Polymerase 1 (PARP1) Antikörper
  • BEST:LD21673
  • CG17685
  • CG17696
  • CG17718
  • CG40411
  • D.PARP
  • Dm.pARTa
  • Dmel\\CG40411
  • LD21673.3prime
  • PARP
  • PARP-1
  • PARP1
  • dPARP
  • parp
  • ADPRT
  • ADPRT 1
  • ADPRT1
  • ARTD1
  • PPOL
  • pADPRT-1
  • Adprt
  • Parp-1
  • adprt1
  • padprt-1
  • ppol
  • 5830444G22Rik
  • AI893648
  • Adprp
  • Adprt1
  • C80510
  • parp-1
  • sPARP-1
  • Poly-(ADP-ribose) polymerase
  • poly (ADP-ribose) polymerase 1
  • poly (ADP-ribose) polymerase family, member 1
  • poly ADP-ribose polymerase
  • Parp
  • PARP1
  • Parp1
  • parp1
Epitop
N-Term
57
19
19
19
19
19
19
19
18
18
18
17
15
12
12
9
9
8
8
6
5
5
4
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
383
84
81
18
17
13
9
9
7
6
5
3
2
2
1
1
1
1
1
Wirt
Kaninchen
376
46
1
Klonalität
Polyklonal
Konjugat
Dieser PARP1 Antikörper ist unkonjugiert
25
24
24
24
24
23
Applikation
Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
237
230
164
50
45
41
31
22
13
12
6
4
4
3
2
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN2668274
497,22 €
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
34.308746 ABIN2668275 ChIP WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 1
1 ABIN2667772 ChIP WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN2667771 ChIP WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal

anti-PARP1 Antikörper für Chromatin Immunoprecipitation mit den meisten Publikationen

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Applikation / Reaktivität Human
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ELISA 213 Antikörper
Enzyme Immunoassay (EIA) 4 Antikörper
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Immunofluorescence (fixed cells) (IF/ICC) 3 Antikörper
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Immunohistochemistry (IHC) 43 Antikörper
Immunohistochemistry (Frozen Sections) (IHC (fro)) 6 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 43 Antikörper
Immunoprecipitation (IP) 34 Antikörper
Neutralization (Neut) 1 Antikörper
Proximity Ligation Assay (PLA) 1 Antikörper

General

Antigen Poly (ADP-Ribose) Polymerase 1 (PARP1) Antikörper
Epitop N-Term
(57), (19), (19), (19), (19), (19), (19), (19), (18), (18), (18), (17), (15), (12), (12), (9), (9), (8), (8), (6), (5), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(383), (84), (81), (18), (17), (13), (9), (9), (7), (6), (5), (3), (2), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(376), (46), (1)
Klonalität
Polyklonal
Konjugat Dieser PARP1 Antikörper ist unkonjugiert
(25), (24), (24), (24), (24), (23)
Applikation Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
(237), (230), (164), (50), (45), (41), (31), (22), (13), (12), (6), (4), (4), (3), (2), (1), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-PARP1 Antikörper

Target Details PARP1 Anwendungsinformationen Handhabung ProductDetails: References for anti-PARP1 antibody (ABIN2668274) Bilder
Reinigung None
Immunogen This PARP-1 N-terminal antibody was raised against a His-tagged fusion protein corresponding to the N-terminal half of human PARP-1 was used to generate this PARP-1 antibody.

Target Details PARP1

Produktdetails anti-PARP1 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-PARP1 antibody (ABIN2668274) Bilder zurück nach oben
Antigen
Andere Bezeichnung PARP-1 (PARP1 Antibody Abstract)
Hintergrund PARP-1 N-terminal (ADPRT) encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, that modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation and tumor transformation. It also plays a role in the regulation of the molecular events involved in the recovery of cells from DNA damage. Cleavage of PARP-1 (ADPRT) occurs following caspase activation during apoptosis. For additional information on PARP-1, please see the review article PARP-1: An Abundant and Ubiquitous Protein with Roles in Many Cellular Processes in the Targets & Applications section or our website.
Molekulargewicht 120 kDa
Gen-ID 142
Forschungsgebiet Enzymes
Pathways Apoptose, Caspase Kaskade in der Apoptose, DNA Reparatur, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location

Anwendungsinformationen

Produktdetails anti-PARP1 Antikörper Target Details PARP1 Handhabung ProductDetails: References for anti-PARP1 antibody (ABIN2668274) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-PARP1 Antikörper Target Details PARP1 Anwendungsinformationen ProductDetails: References for anti-PARP1 antibody (ABIN2668274) Bilder zurück nach oben
Format Liquid
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Lagerung -20 °C
Informationen zur Lagerung Antibodies in solution can be stored at -20 °C for 2 years.
Haltbarkeit 6 months

ProductDetails: References for anti-PARP1 antibody (ABIN2668274)

Produktdetails anti-PARP1 Antikörper Target Details PARP1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Myers, Peddada, Chatterjee, Friedrich, Tomoda, Krings, Thomas, Maynard, Broeker, Thomson, Pollard, Yamanaka, Burlingame, Panning: "SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells." in: eLife, Vol. 5, pp. e10647, 2016

Watanabe, Papoutsoglou, Maturi, Tsubakihara, Hottiger, Heldin, Moustakas: "Regulation of Bone Morphogenetic Protein Signaling by ADP-ribosylation." in: The Journal of biological chemistry, Vol. 291, Issue 24, pp. 12706-23, 2016

Matveeva, Maiorano, Zhang, Eteleeb, Convertini, Chen, Infantino, Stamm, Wang, Rouchka, Fondufe-Mittendorf: "Involvement of PARP1 in the regulation of alternative splicing." in: Cell discovery, Vol. 2, pp. 15046, 2016

Krishnakumar, Gamble, Frizzell, Berrocal, Kininis, Kraus: "Reciprocal binding of PARP-1 and histone H1 at promoters specifies transcriptional outcomes." in: Science (New York, N.Y.), Vol. 319, Issue 5864, pp. 819-21, 2008

Kim, Mauro, Gévry, Lis, Kraus: "NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1." in: Cell, Vol. 119, Issue 6, pp. 803-14, 2004

Bilder

Produktdetails anti-PARP1 Antikörper Target Details PARP1 Anwendungsinformationen Handhabung ProductDetails: References for anti-PARP1 antibody (ABIN2668274) zurück nach oben
Bilder des Herstellers
Chromatin Immunoprecipitation (ChIP) image for anti-PARP1 Antikörper (Poly (ADP-Ribose) Polymerase 1) (N-Term) (ABIN2668274) PARP-1 N-terminal antibody tested by ChIP analysis. Chromatin IP performed with chrom...
Western Blotting (WB) image for anti-PARP1 Antikörper (Poly (ADP-Ribose) Polymerase 1) (N-Term) (ABIN2668274) PARP-1 N-terminal antibody tested by Western blot. HeLa cell nuclear extract (20 µg p...