anti-Human FADD Antikörper für Immunofluorescence (Paraffin-embedded Sections)

Recommended FADD Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Fas (TNFRSF6)-Associated Via Death Domain (FADD) Antikörper
  • MORT1
  • Mort1/FADD
  • Mort1
  • TNFRSF6
  • Fas (TNFRSF6)-associated via death domain
  • FADD
  • Fadd
Epitop
pSer194
32
29
25
20
20
17
14
9
7
6
5
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human
220
81
38
11
3
2
Wirt
Kaninchen
176
97
Klonalität
Polyklonal
Konjugat
Dieser FADD Antikörper ist unkonjugiert
11
10
9
7
5
5
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
242
145
87
49
28
15
14
7
5
4
4
3
1
1
Optionen
Hersteller
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Produktnummer ABIN713426
326,42 €
Zzgl. Versandkosten 20,00 € und MWSt

Ähnliche anti-FADD Antikörper

Applikation / Reaktivität Human
ELISA 120 Antikörper
ELISA (Capture) 1 Antikörper
Enzyme Immunoassay (EIA) 5 Antikörper
Flow Cytometry (FACS) 4 Antikörper
Immunochromatography (IC) 4 Antikörper
Immunocytochemistry (ICC) 6 Antikörper
Immunofluorescence (IF) 15 Antikörper
Immunofluorescence (fixed cells) (IF/ICC) 2 Antikörper
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antikörper
Immunohistochemistry (IHC) 65 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 44 Antikörper
Immunoprecipitation (IP) 27 Antikörper
Proximity Ligation Assay (PLA) 1 Antikörper
Western Blotting (WB) 203 Antikörper

General

Antigen Fas (TNFRSF6)-Associated Via Death Domain (FADD) Antikörper
Epitop pSer194
(32), (29), (25), (20), (20), (17), (14), (9), (7), (6), (5), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(220), (81), (38), (11), (3), (2)
Wirt Kaninchen
(176), (97)
Klonalität
Polyklonal
Konjugat Dieser FADD Antikörper ist unkonjugiert
(11), (10), (9), (7), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(242), (145), (87), (49), (28), (15), (14), (7), (5), (4), (4), (3), (1), (1)
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Produktdetails anti-FADD Antikörper

Target Details FADD Anwendungsinformationen Handhabung Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human FADD around the phosphorylation site of Ser194
Isotyp IgG

Target Details FADD

Produktdetails anti-FADD Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Fadd (FADD Antibody Abstract)
Hintergrund

FADD (Fas Associated Death Domain) is an apoptosis adapter molecule enabling transduction of the apoptosis signal initiated via the FasL/Fas receptor interaction. The protein contains a C terminal death domain that interacts with the Fas receptor death domain. The N terminus contains a death effectors domain (DED) which recruits caspase to the death inducing signaling complex (DISC) and initiates the apoptotic caspase cascade. Recruitment of Caspase 8 to the Fas receptor results in oligomerization of the Caspase 8 protein, which in turn drives its autoactivation through self-cleavage. Activated Caspase 8 then activates other downstream caspases including Caspase 9, thereby commiting the cell to undergo apoptosis. FADD is implicated in non-apoptotic cellular pathways such as the regulation of cell cycle machinery in T lymphocytes. This is connected to the phosphorylation state of FADD and to the FasL/TRAIL induced transcriptional activation of cfos protooncogene. FADD also interacts with the hepatitis C virus core protein in the HEK 293 cell line.

Synonyms: P-Fas-associated protein with death domain, FADD protein, Fas TNFRSF6 associated via death domain, Fas associated via death domain, Fas associating death domain containing protein, Fas associating protein, Fas associating protein with death domain, Fas TNFRSF6 associated via death domain, GIG 3, GIG3, Growth inhibiting gene 3 protein, H sapiens mRNA for mediator of receptor induced toxicity, Mediator of receptor induced toxicity , MGC8528 , MORT 1, MORT1, FADD_HUMAN.

Gen-ID 8772
Forschungsgebiet Cancer, Apoptosis/Necrosis
Pathways Apoptose, TLR Signalweg, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-FADD Antikörper Target Details FADD Handhabung Bilder zurück nach oben
Applikationshinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-FADD Antikörper Target Details FADD Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months