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TRKA Antikörper (AA 33-423)

Name: TRKA Antikörper (AA 33-423)
Brand: antibodies-online
SKU: ABIN969444
Price: 562.94 EUR
Availability: InStock

NTRK1 Reaktivität: Human WB, ELISA, ICC Wirt: Maus Monoclonal 6B2 unconjugated

Western blot analysis using TrkA mouse mAb against extracellular domain of human TrkA(aa33-423). (TRKA Antikörper (AA 33-423))

Confocal immunofluorescence analysis of PC-12 cells using TrkA mouse mAb (green), showing membrane and cytoplasmic localization. (TRKA Antikörper (AA 33-423))

2 Abbildungen

(2 Referenzen)

Produktnummer ABIN969444

Datenblatt (PDF)

Target Alle TRKA (NTRK1) Antikörper anzeigen

TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
Bindungsspezifität
36

26

25

19

16

15

15

10

10

9

8

8

8

6

5

4

4

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 33-423
Reaktivität
237

151

144

15

4

4

1

1
Human
Wirt
247

14

3

2
Maus
Passende Sekundärantikörper
Klonalität
239

26

1
Monoklonal
Konjugat
100

18

15

13

11

11

11

11

11

11

8

6

6

6

6

6

6

2

2

1

1

1

1

1

1
Dieser TRKA Antikörper ist unkonjugiert
Applikation
183

98

79

78

50

38

30

20

19

14

8

5

4

3

2

2

2

1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Aufreinigung

purified

Immunogen

Purified recombinant extracellular fragment of human TrkA (aa33-423) fused with hIgGFc tag expressed in HEK293 cell line.

Klon

6B2

Isotyp

IgG1

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anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (AA 725-821) antibody
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anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (AA 33-208) antibody
NTRK1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) antibody
NTRK1 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (Extracellular Domain) antibody
NTRK1 Reaktivität: Human WB, ELISA, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (C-Term) antibody
NTRK1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (AA 769-796) antibody
NTRK1 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) antibody
NTRK1 Reaktivität: Human, Maus WB, ELISA, IF, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (2nd Extracellular Domain), (AA 342-356) antibody
NTRK1 Reaktivität: Human, Maus, Ratte WB, IHC, IF, FACS, ICC, LCI Wirt: Kaninchen Polyclonal unconjugated

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (pTyr496) antibody
NTRK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

4°C, -20°C for long term storage
Geetha, Wooten: "TrkA receptor endolysosomal degradation is both ubiquitin and proteasome dependent." in: Traffic (Copenhagen, Denmark), Vol. 9, Issue 7, pp. 1146-56, (2008) (PubMed).

Schulte, Kuhfittig-Kulle, Klein-Hitpass, Schramm, Biard, Pfeiffer, Eggert: "Expression of the TrkA or TrkB receptor tyrosine kinase alters the double-strand break (DSB) repair capacity of SY5Y neuroblastoma cells." in: DNA repair, Vol. 7, Issue 10, pp. 1757-64, (2008) (PubMed).
Target

TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))

Andere Bezeichnung

TrkA (NTRK1 Produkte)

Synonyme

MTC antikoerper, TRK antikoerper, TRK1 antikoerper, TRKA antikoerper, Trk-A antikoerper, p140-TrkA antikoerper, CDHF12 antikoerper, CDHR16 antikoerper, HSCR1 antikoerper, MEN2A antikoerper, MEN2B antikoerper, MTC1 antikoerper, PTC antikoerper, RET-ELE1 antikoerper, RET51 antikoerper, Trk antikoerper, C80751 antikoerper, Tkr antikoerper, TrkA antikoerper, trk antikoerper, trka antikoerper, CTRKA antikoerper, trkA antikoerper, neurotrophic receptor tyrosine kinase 1 antikoerper, ret proto-oncogene antikoerper, neurotrophic tyrosine kinase, receptor, type 1 antikoerper, NTRK1 antikoerper, RET antikoerper, Ntrk1 antikoerper, ntrk1 antikoerper

Hintergrund

Description: TrkA, also known as NTRK1, MTC, TRK, TRK1. It is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Aliases: NTRK1, MTC, TRK, TRK1

Molekulargewicht

87.4 kDa

Gen-ID

4914

HGNC

4914

Pathways

RTK Signalweg, Neurotrophin Signalübertragung, cAMP Metabolic Process