FZD6 Antikörper (Middle Region)
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- Target Alle FZD6 Antikörper anzeigen
- FZD6 (Frizzled Family Receptor 6 (FZD6))
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Bindungsspezifität
- AA 493-520, Middle Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FZD6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody recognizes Human FZD6 (Center).
- Aufreinigung
- Protein A column, followed by peptide affinity purification
- Immunogen
- KLH conjugated synthetic peptide between 493-520 amino acids from the Central region of human FZD6
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product FZD6 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- FZD6 (Frizzled Family Receptor 6 (FZD6))
- Andere Bezeichnung
- FZD6 (FZD6 Produkte)
- Synonyme
- zgc:65879 antikoerper, zgc:77440 antikoerper, fz6 antikoerper, frz6 antikoerper, Xfrz6 antikoerper, frizzled6 antikoerper, frizzled-6 antikoerper, FZ-6 antikoerper, FZ6 antikoerper, HFZ6 antikoerper, NDNC10 antikoerper, Frizzled-6 antikoerper, Fz6 antikoerper, frizzled class receptor 6 antikoerper, frizzled class receptor 6 S homeolog antikoerper, fzd6 antikoerper, fzd6.S antikoerper, FZD6 antikoerper, Fzd6 antikoerper
- Hintergrund
- This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants.Synonyms: Frizzled-6, Fz-6, hFz6
- Molekulargewicht
- 79292 Da
- Gen-ID
- 8323
- NCBI Accession
- NP_001158087
- Pathways
- WNT Signalweg, Tube Formation
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