Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (AA 320-356) Antikörper

Details zu Produkt Nr. ABIN748373, Anbieter: Anmelden zum Anzeigen
Antigen
  • erk1/2
  • mitogen-activated protein kinase
  • erk1/2
Epitop
AA 320-356
129
127
35
34
30
19
18
15
15
15
15
14
12
9
9
9
9
8
6
5
4
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Kaninchen, Ratte (Rattus)
421
320
304
57
23
14
9
8
8
7
7
6
5
5
3
3
2
2
2
1
1
1
1
Wirt
Kaninchen
349
78
7
Klonalität
Polyklonal
Konjugat
Unkonjugiert
12
11
11
10
7
7
7
7
6
6
6
6
6
6
2
2
2
2
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
305
114
83
77
59
56
46
42
16
10
6
4
4
4
2
2
2
1
Optionen
Hersteller
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Immunogen KLH conjugated synthetic peptide derived from mouse ERK2
Isotyp IgG
Reinigung Purified by Protein A.
Andere Bezeichnung Erk1 + 2 (MAPK1/3 Antibody Abstract)
Sub Type Cocktail
Hintergrund

The protein encoded by this gene is a member of the MAPkinase family. MAP kinases, also known as extracellularsignal-regulated kinases (ERKs), act in a signaling cascade thatregulates various cellular processes such as proliferation,differentiation, and cell cycle progression in response to avariety of extracellular signals. This kinase is activated byupstream kinases, resulting in its translocation to the nucleuswhere it phosphorylates nuclear targets. Alternatively splicedtranscript variants encoding different protein isoforms have beendescribed. [provided by RefSeq, Jul 2008].

Subcellular location: Cytoplasm, Nucleus

Synonyms: ERK, Erk2, MAPK2, PRKM2, Prkm1, C78273, p41mapk, p42mapk, AA47128, AU18647, 93612K14Rik, Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, Mapk1, Mapk

Gen-ID 26413
UniProt P63085
Applikationshinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (AA 320-356) antibody (ABIN748373) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti ER...
SDS-PAGE (SDS) image for anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (AA 320-356) antibody (ABIN748373) Lane 1: mouse heart lysates Lane 2: mouse brain lysates probed with Anti ERK1/2(p42/p...
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (AA 320-356) antibody (ABIN748373) A549 cell lysates probed with Rabbit Anti-ERK1 + 2 Polyclonal Antibody, Unconjugated ...
Produkt verwendet in: Cong, Chen: "Neuroprotective Effect of Ginsenoside Rd in Spinal Cord Injury Rats." in: Basic & clinical pharmacology & toxicology, Vol. 119, Issue 2, pp. 193-201, 2016 (PubMed).

Yu, Shi, Qi, Zhao, Gao, Li: "Gypenoside Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of Mitogen-Activated Protein Kinase Mediated Nuclear Factor Kappa B Pathway In Vitro and In Vivo." in: Frontiers in pharmacology, Vol. 7, pp. 148, 2016 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Rat (Rattus)).

Zhao, Xue, Guo, Sun, Liu, Wang: "Inhibition of endocan attenuates monocrotaline-induced connective tissue disease related pulmonary arterial hypertension." in: International immunopharmacology, Vol. 42, pp. 115-121, 2016 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Rat (Rattus)).

Wang, Zhao, Guo, Zhang, Pei: "Picroside II Inhibits Neuronal Apoptosis and Improves the Morphology and Structure of Brain Tissue following Cerebral Ischemic Injury in Rats." in: PLoS ONE, Vol. 10, Issue 4, pp. e0124099, 2015 (PubMed).

Wang, Zhai, Guo, Pei, Zhang: "Picroside II has a neuroprotective effect by inhibiting ERK1/2 activation after cerebral ischemic injury in rats." in: Clinical and experimental pharmacology & physiology, 2015 (PubMed).

Chen, Bao, Chen, Burton, Gong, Gu, Mi, Bao: "Mycobacterium tuberculosis PE25/PPE41 protein complex induces activation and maturation of dendritic cells and drives Th2-biased immune responses." in: Medical microbiology and immunology, 2015 (PubMed).

Zhao, Liu, Liu, Han, Zhao: "Betulin attenuates lung and liver injuries in sepsis." in: International immunopharmacology, Vol. 30, pp. 50-6, 2015 (PubMed).

An, Dang, Shi, Ye, Wu: ""Qufeng Tongluo" acupuncture prevents the progression of glomerulonephritis by decreasing renal sympathetic nerve activity." in: Journal of ethnopharmacology, Vol. 155, Issue 1, pp. 277-84, 2014 (PubMed).

Xu, Guo, Gao, Shi, He, Gao, Zhang: "Acyldepsipeptides inhibit the growth of renal cancer cells through G1 phase cell cycle arrest." in: Biochemical and biophysical research communications, Vol. 438, Issue 3, pp. 468-72, 2013 (PubMed).

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