MTOR Antikörper (pSer2481)
Kurzübersicht für MTOR Antikörper (pSer2481) (ABIN482059)
Target
Alle MTOR (mTOR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 2447-2496, pSer2481
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Spezifität
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mTOR (Phospho-Ser2481) Antibody detects endogenous levels of mTOR only when phosphorylated at Ser2481.
PhosphorylationH:S2481 M:S2481 R:S2481
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Aufreinigung
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human mTOR around the phosphorylation site of Ser2481.
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Isotyp
- IgG
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Applikationshinweise
- IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:20000
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Kommentare
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Unigene-Number: Hs.338207 (NCBI Gene Symbol: MTOR)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable at -20°C for at least 1 year.
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Haltbarkeit
- 12 months
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- MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))
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Andere Bezeichnung
- mTOR
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Hintergrund
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Synonyms: FRAP, FRAP1, FRAP2, RAFT1, Rapamycin target protein, kinase mTOR
NCBI Gene Symbol: MTOR
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Molekulargewicht
- 288 kDa
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Gen-ID
- 2475
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OMIM
- 601231
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UniProt
- P42345
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Pathways
- PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagie, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effekt
Target
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