RASGRF1 Antikörper (Ser929)

Produktnummer ABIN359752

Produktdetails anti-RASGRF1 Antikörper

Target: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Bindungsspezifität: Ser929

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASGRF1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to RASGRF1.

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S929 of human RASGRF1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu RASGRF1

Target: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Andere Bezeichnung: RASGRF1 (RASGRF1 Produkte)

Synonyme: CDC25 antikoerper, CDC25L antikoerper, GNRP antikoerper, GRF1 antikoerper, GRF55 antikoerper, H-GRF55 antikoerper, PP13187 antikoerper, ras-GRF1 antikoerper, AI844718 antikoerper, CDC25Mm antikoerper, Grf1 antikoerper, Grfbeta antikoerper, P190-A antikoerper, Ras-GRF1 antikoerper, p190 antikoerper, p190RhoGEF antikoerper, cdc25 antikoerper, rasgrf1 antikoerper, Ras protein specific guanine nucleotide releasing factor 1 antikoerper, RAS protein-specific guanine nucleotide-releasing factor 1 antikoerper, Ras protein specific guanine nucleotide releasing factor 1 S homeolog antikoerper, si:ch211-234p18.3 antikoerper, RASGRF1 antikoerper, Rasgrf1 antikoerper, rasgrf1.S antikoerper, si:ch211-234p18.3 antikoerper, rasgrf1 antikoerper

Hintergrund: RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. Studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory.Synonyms: CDC25, GNRP, GRF1, Guanine nucleotide-releasing protein, Ras-GRF1, Ras-specific guanine nucleotide-releasing factor 1, Ras-specific nucleotide exchange factor CDC25

Gen-ID: 5923, 9606

UniProt: Q13972

Pathways: RTK Signalweg, Zellzyklus, M Phase