ATP2A2 Antikörper (C-Term)
-
- Target Alle ATP2A2 Antikörper anzeigen
- ATP2A2 (ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2))
-
Bindungsspezifität
- C-Term
-
Reaktivität
- Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio)
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser ATP2A2 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- VNLVTDGLPA TALGFNPPDL DIMNKPPRNP KEPLISGWLF FRYLAIGCYV
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against ATP2A2. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human ATP2A2
- Top Product
- Discover our top product ATP2A2 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 1042 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- ATP2A2 (ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2))
- Andere Bezeichnung
- ATP2A2 (ATP2A2 Produkte)
- Synonyme
- atp2b antikoerper, ca-p60a antikoerper, dar antikoerper, serca2 antikoerper, ATP2A2 antikoerper, ATP2B antikoerper, DAR antikoerper, DD antikoerper, SERCA2 antikoerper, SERCA2A antikoerper, ATP2 antikoerper, Serca2 antikoerper, SercaII antikoerper, 9530097L16Rik antikoerper, D5Wsu150e antikoerper, SERCA2B antikoerper, mKIAA4195 antikoerper, atp2a2 antikoerper, zgc:55380 antikoerper, ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 S homeolog antikoerper, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 antikoerper, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 antikoerper, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a antikoerper, atp2a1.S antikoerper, ATP2A2 antikoerper, Atp2a2 antikoerper, atp2a2a antikoerper
- Hintergrund
-
ATP2A2 is one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in two transcript variants encoding different isoforms.
Alias Symbols: ATP2B, DAR, DD, DKFZp686P0211, FLJ20293, FLJ38063, MGC45367, SERCA2
Protein Interaction Partner: ERLIN2, UBC, SUMO2, SPRTN, PTPLAD1, LGR4, MDM2, ASB14, ASB5, ASB17, ASB1, TRIM13, SUZ12, RNF2, EZH2, rev, S100A1, EGFR, ADRB2, ILK, CLN5, CLN3, env, NOS2, ATF2, CFTR, MDC1, ECT2, SLC3A2, ITPR3, CUL3, FBXO25, SPP1, SIRT7, ELAVL1, SUMO1, AMFR, HDAC5, CAMK2A
Protein Size: 1042 - Molekulargewicht
- 115 kDa
- Gen-ID
- 488
- NCBI Accession
- NM_170665, NP_733765
- UniProt
- P16615
- Pathways
- Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Ribonucleoside Biosynthetic Process
-