PPP2R1A Antikörper (Protein Phosphatase 2, Regulatory Subunit A, alpha) (N-Term)

Details for Product anti-PPP2R1A Antibody No. ABIN2774161, Anbieter: Anmelden zum Anzeigen
Antigen
  • pp2a-aalpha
  • pp2aaalpha
  • pr65a
  • c-sis
  • pdgf2
  • ppp2r1a
  • sis
  • ssv
  • 6330556D22Rik
  • PP2A
  • PR65
  • wu:fa02h04
  • zgc:56296
  • PP2A-Aalpha
  • PP2AAALPHA
  • PR65A
  • protein phosphatase 2 regulatory subunit A, alpha
  • platelet-derived growth factor beta polypeptide
  • protein phosphatase 2 scaffold subunit Aalpha
  • serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
  • protein phosphatase 2, regulatory subunit A, alpha isoform
  • protein phosphatase 2, regulatory subunit A, alpha
  • protein phosphatase 2, regulatory subunit A, beta a
  • protein phosphatase 2 scaffold subunit A alpha
  • protein phosphatase 2 regulatory subunit A, alpha L homeolog
  • ppp2r1a
  • pdgfb
  • PPP2R1A
  • LOC583227
  • Ppp2r1a
  • ppp2r1ba
  • ppp2r1a.L
Epitop
N-Term
24
18
10
4
3
2
2
2
2
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Ratte (Rattus), Zebrafisch
96
50
45
15
9
7
6
6
5
5
4
2
2
1
1
Wirt
Kaninchen
75
13
8
2
Klonalität
Polyklonal
Konjugat
Dieser PPP2R1A Antikörper ist unkonjugiert
4
4
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
76
34
18
15
13
8
7
5
5
3
2
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human PPP2R1A
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN982118.
Sequenz KAVESLRAIS HEHSPSDLEA HFVPLVKRLA GGDWFTSRTS ACGLFSVCYP
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 85%
Produktmerkmale This is a rabbit polyclonal antibody against PPP2R1A. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung PPP2R1A (PPP2R1A Antibody Abstract)
Hintergrund PPP2R1A is a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. PPP2R1A is an alpha isoform of the constant regulatory subunit A.This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC786, PR65A, PP2AAALPHA, PP2A-Aalpha
Protein Interaction Partner: CSDC2, UBC, PPP2R2A, PPP2R1B, PPP2CB, POLDIP2, MOB4, SRGAP2, ANKLE2, PSIP1, ESPL1, PPFIA3, PPFIA1, IRS4, CCDC6, TFAM, PPP1R12B, HSPA7, HSPA1A, FECH, CTNNA2, CLCN6, STRN, RPS19, RPS3, PPP2R5E, PPP2R5D, PPP2R5C, PPP2CA, PEX1, LOC730668, DGKH, RAVER1, CCDC43
Protein Size: 589
Molekulargewicht 65 kDa
Gen-ID 5518
NCBI Accession NM_014225, NP_055040
UniProt P30153
Forschungsgebiet Signaling, Kinases/Phosphatases
Pathways PI3K-Akt Signalweg, Mitotic G1-G1/S Phases, M Phase, Hepatitis C, Toll-Like Receptors Cascades
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 589 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A) (N-Term) antibody (ABIN2774161) Host: Mouse Target Name: PPP2R1A Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml
Western Blotting (WB) image for anti-Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A) (N-Term) antibody (ABIN2774161) WB Suggested Anti-PPP2R1A Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Posi...
Allgemeine Veröffentlichungen Hong, Wang, Gao, Kuo, Liu, Merling, Kung, Shih, Giam: "Heptad repeats regulate protein phosphatase 2a recruitment to I-kappaB kinase gamma/NF-kappaB essential modulator and are targeted by human T-lymphotropic virus type 1 tax." in: The Journal of biological chemistry, Vol. 282, Issue 16, pp. 12119-26, 2007 (PubMed).

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