Paxillin Antikörper (C-Term)
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- Target Alle Paxillin (PXN) Antikörper anzeigen
- Paxillin (PXN)
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Bindungsspezifität
- AA 305-559, C-Term
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Reaktivität
- Human, Maus, Ratte, Huhn
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Paxillin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Spezifität
- This antibody reacts to Paxillin.
- Aufreinigung
- Affinity chromatography
- Immunogen
- C-terminal part of recombinant chicken paxillin (amino acids 305-559)
- Klon
- PAX-14
- Isotyp
- IgG1
- Top Product
- Discover our top product PXN Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- Restore with 1.2 % sodium acetate or neutral PBS
- Konzentration
- 0,1 mg/mL
- Buffer
- 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Paxillin (PXN)
- Andere Bezeichnung
- Paxillin / PXN (PXN Produkte)
- Synonyme
- AW108311 antikoerper, AW123232 antikoerper, Pax antikoerper, CG18061 antikoerper, CG18576 antikoerper, CG31794 antikoerper, CT40481 antikoerper, CT42454 antikoerper, DPaxillin antikoerper, DPxn antikoerper, DPxn37 antikoerper, Dmel\\CG31794 antikoerper, Dpax antikoerper, DpaxA antikoerper, PDLP antikoerper, dPax antikoerper, pax antikoerper, wu:fw71f12 antikoerper, PXN antikoerper, LOC100220858 antikoerper, paxillin antikoerper, Paxillin antikoerper, paxillin S homeolog antikoerper, paxillin a antikoerper, PXN antikoerper, Pxn antikoerper, Pax antikoerper, pxn.S antikoerper, pxna antikoerper, LOC696336 antikoerper, pxn antikoerper
- Hintergrund
- The paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68- kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells.Synonyms: FLJ16691
- Gen-ID
- 5829
- NCBI Accession
- NP_001074324
- UniProt
- P49023
- Pathways
- MAPK Signalweg, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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