anti-TNFSF9 (TNFSF9) Antikörper

Bezeichnung:
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 9 Antikörper (TNFSF9)
Auf www.antikoerper-online.de finden Sie aktuell 226 Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) Antikörper von 23 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TNFSF9 Proteine (47) und TNFSF9 Kits (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 290 TNFSF9 Produkte verfügbar.
Synonyme:
4-1BB-L, 4-1BBL, AI848817, CD137L, Ly63l, TNFSF9
Alle Antikörper anzeigen Gen GeneID UniProt
TNFSF9 353218  
TNFSF9 21950 P41274
TNFSF9 8744 P41273

Alle Spezies anzeigen

Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-TNFSF9 (TNFSF9) Antikörper

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anti-Rat (Rattus) TNFSF9 Antikörper:

anti-Mouse (Murine) TNFSF9 Antikörper:

anti-Human TNFSF9 Antikörper:

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Am meisten referenzierte anti-TNFSF9 Antikörper

  1. Mouse (Murine) Monoclonal TNFSF9 Primary Antibody für FACS - ABIN2660885 : Pollok, Kim, Kwon: Regulation of 4-1BB expression by cell-cell interactions and the cytokines, interleukin-2 and interleukin-4. in European journal of immunology 1995 (PubMed)
    Zeige alle 10 Referenzen für 2660885

  2. Mouse (Murine) Polyclonal TNFSF9 Primary Antibody für ELISA - ABIN2000265 : Cheung, Deisher, Luo, Yanagawa, Bonigut, Samra, Zhao, Walker, McManus: Neutralizing anti-4-1BBL treatment improves cardiac function in viral myocarditis. in Laboratory investigation; a journal of technical methods and pathology 2007 (PubMed)
    Zeige alle 2 Referenzen für 2000265

  3. Human Polyclonal TNFSF9 Primary Antibody für FACS, IHC - ABIN4900479 : Ek, Björck, Högerkorp, Nordenskjöld, Porwit-MacDonald, Borrebaeck: Mantle cell lymphomas acquire increased expression of CCL4, CCL5 and 4-1BB-L implicated in cell survival. in International journal of cancer 2006 (PubMed)

  4. Mouse (Murine) Monoclonal TNFSF9 Primary Antibody für FACS, IP - ABIN320112 : Goodwin, Din, Davis-Smith, Anderson, Gimpel, Sato, Maliszewski, Brannan, Copeland, Jenkins: Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor. in European journal of immunology 1993 (PubMed)

  5. Human Monoclonal TNFSF9 Primary Antibody für ICC, FACS - ABIN1169256 : Gullo, Koh, Pang, Ho, Tan, Schwarz: Inhibition of proliferation and induction of apoptosis in multiple myeloma cell lines by CD137 ligand signaling. in PLoS ONE 2010 (PubMed)

Weitere Antikörper gegen TNFSF9 Interaktionspartner

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) Interaktionspartner

  1. Constitutive interaction between 4-1BB (zeige TNFRSF9 Antikörper) and 4-1BBL on murine LPS (zeige TLR4 Antikörper)-activated bone marrow dendritic cells masks detection of 4-1BBL by TKS (zeige PTK6 Antikörper)-1 but not 19H3 antibody.

  2. 4-1BBL can restrain effector T cell development, creating a more favorable regulatory T cell to effector cell balance under tolerogenic conditions, and this may be particularly active in mucosal barrier tissues

  3. These results demonstrate that 4-1BBL-engineered DCs can improve CIKs (zeige TRAF3IP2 Antikörper) cytotoxicity against prostate cancer cells.

  4. these observations suggest that inhibition of the TLR/4 (zeige TLR4 Antikörper)-1BBL complex formation may be highly efficient in protecting against continued inflammation

  5. 4-1BB (zeige TNFRSF9 Antikörper) mediates the inflammatory responses in obese skeletal muscle by interacting with its ligand 4-1BBL on macrophages.

  6. CD137 (zeige TNFRSF9 Antikörper)-CD137L interactions mediated via regulation of CyPA (zeige PPIA Antikörper) contribute to the progression of atherosclerosis.

  7. Data indicate that CD137L deficient mice displayed a variety of immunological dysfunctions.

  8. monocytes interact with iNKT cells to increase expression of 4-1BBL and 4-1BB (zeige TNFRSF9 Antikörper), and in conjunction with this pathway, maintain their numbers at baseline.

  9. CD137 (zeige TNFRSF9 Antikörper)-expressing CD4 (zeige CD4 Antikörper)+ T cells in the bone marrow engage CD137L on hematopoietic progenitor cells, and this CD137L signaling biases hematopoiesis towards myelopoiesis during aging.

  10. TIRAP (zeige TIRAP Antikörper) and IRAK2 (zeige IRAK2 Antikörper) are critical for the sustained inflammatory response that is mediated by late-phase signaling by the TLR-4 (zeige TLR4 Antikörper)-1BBL complex.

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) Interaktionspartner

  1. blocking of both OX-40L (zeige TNFSF4 Antikörper) and 4-1BBL reversed radiation-enhanced T-cell killing of human tumor targets as well as T-cell survival and activation.

  2. CD137L is overexpressed in non-small cell lung cancer specimens and positive expression of CD137L was associated with better overall survival.

  3. In vitro immunotherapy is described for anti-prostate cancer effects of cytotoxic T lymphocytes induction by recombinant adenovirus mediated PSMA/4 (zeige PSMA4 Antikörper)-1BBL dendritic cells.

  4. vaccination with recombinant attenuated Salmonella harboring the CEACAM6 and 4-1BBL gene efficiently increased the number of CD3 (zeige CD3 Antikörper)+CD8 (zeige CD8A Antikörper)+ TIL (zeige TLR1 Antikörper) and NK cells, decreased the number of FOXP3 (zeige FOXP3 Antikörper) cells and inhibited the development of DMH (zeige DST Antikörper)-induced colorectal cancer

  5. Elevated plasma levels and monocyte-associated expression of CD137 (zeige TNFRSF9 Antikörper) ligand in patients with acute atherothrombotic stroke

  6. Hence, the targeted combination of IL-15 (zeige IL15 Antikörper) and 4-BBL (zeige TP53 Antikörper) in the form of a trifunctional antibody-fusion protein is a promising new approach for cancer immunotherapy.

  7. monocytes interact with iNKT cells to increase expression of 4-1BBL and 4-1BB (zeige TNFRSF9 Antikörper), and in conjunction with this pathway, maintain their numbers at baseline.

  8. TIRAP (zeige TIRAP Antikörper) and IRAK2 (zeige IRAK2 Antikörper) are critical for the sustained inflammatory response that is mediated by late-phase signaling by the TLR-4 (zeige TLR4 Antikörper)-1BBL complex.

  9. this is the first study to indicate that this member of the TNF (zeige TNF Antikörper) superfamily, CD137 (zeige TNFRSF9 Antikörper), is modulated by SAHA treatment in breast

  10. Data show that TNFR1 (zeige TNFRSF1A Antikörper) associates with CD137L and is required for CD137L reverse signaling.

TNFSF9 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.

Alternative names and synonyms associated with TNFSF9

  • tumor necrosis factor (ligand) superfamily, member 9 (Tnfsf9) Antikörper
  • tumor necrosis factor (ligand) superfamily, member 9 (TNFSF9) Antikörper
  • 4-1BB-L Antikörper
  • 4-1BBL Antikörper
  • AI848817 Antikörper
  • CD137L Antikörper
  • Ly63l Antikörper
  • TNFSF9 Antikörper

Bezeichner auf Proteinebene für TNFSF9

costimulatory molecule , tumor necrosis factor (ligand) superfamily, member 9 , 4-1BB ligand , tumor necrosis factor ligand superfamily member 9 , 4-1BBL , homolog of mouse 4-1BB-L , receptor 4-1BB ligand

GENE ID SPEZIES
353218 Rattus norvegicus
476729 Canis lupus familiaris
521748 Bos taurus
21950 Mus musculus
8744 Homo sapiens
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