anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) Antikörper

TYROBP encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. Zusätzlich bieten wir Ihnen TYROBP Kits (13) und TYROBP Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TYROBP 361537 Q6X9T7
TYROBP 7305 O43914
TYROBP 22177 O54885
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Showing 10 out of 99 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, FACS, IHC (p), WB TYROBP Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. TYROBP Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TYROBP Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
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Human Kaninchen Unkonjugiert IP, WB 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
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Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: DAP12 Antibody [NBP1-85313] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY403671) Immunohistochemistry-Paraffin: DAP12 Antibody [NBP1-85313] - Staining of human bone marrow shows strong cytoplasmic positivity in hematopoietic cells. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of TYROBP Antibody (C-term) (ABIN653819) in HepG2 cell line lysates (35 µg/lane). TYROBP (arrow) was detected using the purified polyclonal antibody. TYROBP Antibody (C-term) (ABIN653819) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
360,85 €
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Fledermaus Ziege Unkonjugiert IHC (p), ELISA Human Spleen (formalin-fixed, paraffin-embedded) stained with TYROBP antibody ABIN462404 followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. Human Uterus (formalin-fixed, paraffin-embedded) stained with TYROBP antibody ABIN462404 followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
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Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: DAP12 Antibody [NBP2-16099] - Western Blot analysis of TYROBP expression in transfected 293T cell line by TYROBP polyclonal antibody. A: Non-transfected lysate. B: TYROBP transfected lysate. 15% SDS PAGE gel, diluted at 1:500. Immunohistochemistry-Paraffin: DAP12 Antibody [NBP2-16099] - Immunohistochemical analysis of paraffin-embedded H1299 xenograft, using antibody at 1:500 dilution. 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
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Human Ziege Unkonjugiert EIA, IHC (p) Human Spleen (formalin-fixed, paraffin-embedded) stained with TYROBPfollowed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. Human Uterus (formalin-fixed, paraffin-embedded) stained with TYROBPfollowed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
517,00 €
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Human Kaninchen Unkonjugiert IHC (p), WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
801,43 €
Details
Human Maus PE FACS Detection of DAP12 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody. Detection of DAP12 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 3 bis 4 Tage
305,00 €
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TYROBP Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-TYROBP Antikörper

  1. Human Polyclonal TYROBP Primary Antibody für EIA, FACS - ABIN955408 : Chen, Bai, Sokol, Zhou, Ren, Painter, Liu, Sallman, Chen, Yoder, Djeu, Loughran, Epling-Burnette, Wei: A critical role for DAP10 and DAP12 in CD8+ T cell-mediated tissue damage in large granular lymphocyte leukemia. in Blood 2009 (PubMed)
    Zeige alle 3 Referenzen für 955408

  2. Human Polyclonal TYROBP Primary Antibody für IP, WB - ABIN265057 : Lanier, Bakker: The ITAM-bearing transmembrane adaptor DAP12 in lymphoid and myeloid cell function. in Immunology today 2001 (PubMed)
    Zeige alle 2 Referenzen für 265057

  3. Human Polyclonal TYROBP Primary Antibody für IHC, IHC (p) - ABIN4304256 : Preusse, Goebel, Pehl, Rinnenthal, Kley, Allenbach, Heppner, Vorgerd, Authier, Gherardi, Stenzel: Th2-M2 immunity in lesions of muscular sarcoidosis and macrophagic myofasciitis. in Neuropathology and applied neurobiology 2015 (PubMed)

Weitere Antikörper gegen TYROBP Interaktionspartner

Zebrafish TYRO Protein tyrosine Kinase Binding Protein (TYROBP) Interaktionspartner

  1. The structure of the adaptor protein dap12 has been identified in the zebrafish genome.

  2. DAP12-based activating pathway is conserved between bony fish and mammals

Human TYRO Protein tyrosine Kinase Binding Protein (TYROBP) Interaktionspartner

  1. TYROBP influences a batch of genes that are related to Alzheimer's disease; ZNF329 (zeige ZNF329 Antikörper) and RB1 (zeige RB1 Antikörper) significantly regulate those 'mesenchymal' gene expression signature genes for brain tumors. By merely leveraging gene expression data, Context Based Dependency Network (CBDN) can efficiently infer the existence of gene-gene interactions as well as their regulatory directions.

  2. TYROBP/CSTA (zeige CSTA Antikörper) gene interaction might play pivotal roles in the occurrence and development of Postmenopausal Osteoporosis

  3. The different expression of DAP12 compared to TREM2 (zeige TREM2 Antikörper) represents the first description of such variable expressivity in Nasu-Hakola disease (NHD) microglia.

  4. the microglial membrane adaptor protein DAP12 was required for both nerve injury- and intrathecal CSF1 (zeige CSF1 Antikörper)-induced upregulation of pain-related microglial genes and the ensuing pain, but not for microglial proliferation

  5. Impaired signaling by the TREM2 (zeige TREM2 Antikörper)-DAP12 pathway leads to altered immune responses in phagocytosis, cytokine production, and microglial proliferation and survival, thus contributing to disease pathogenesis. Review.

  6. T cells modified to express a KIR (zeige GEM Antikörper)-CAR and DAP12 exhibit superior antitumor activity compared with standard first- and second-generation CD3zeta (zeige CD247 Antikörper)-based CARs in a xenograft model of mesothelioma highly resistant to immunotherapy.

  7. This study reveled that TYROBP having a central role in the bipolar disease and schizophrenia manifestation.

  8. isolated PMNs have an increased proportion of both TREM1 (zeige TREM1 Antikörper) and DAP12 compared to normal healthy control

  9. results support a role of DAP12 in stabilizing TREM2 (zeige TREM2 Antikörper)-CTF (zeige NFIA Antikörper), thereby protecting against excessive pro-inflammatory responses.

  10. Data indicate that NKG2 receptor NKG2E (zeige KLRC3 Antikörper) was capable of associating with CD94 (zeige KLRD1 Antikörper) and DAP12 but that the complex was retained intracellularly at the endoplasmic reticulum.

Mouse (Murine) TYRO Protein tyrosine Kinase Binding Protein (TYROBP) Interaktionspartner

  1. Recent studies have revealed that activated microglia in the spinal dorsal horn exacerbate neuropathic pain, which has suggested that suppression of microglial activity should be considered as a therapeutic target. However, only a few molecules have been identified as regulators of microglial activity. In this study, we focused on a receptor complex of TREM2 (zeige TREM2 Antikörper) and DAP12, both of which are expressed by microglia and have bee

  2. TNF (zeige TNF Antikörper)/IL-6 (zeige IL6 Antikörper) generated osteoclasts in vitro that resorbed mineralized tissue through a pathway dependent on IL-6R, NFATc1 (zeige NFATC1 Antikörper), DNAX-activation protein 12, and cell proliferation.

  3. The findings suggest that DAP12 acts as a brake on the pulmonary immune response to C. neoformans by promoting pulmonary eosinophilia and by inhibiting the activation and antifungal activities of effector cells, including NK cells and macrophages.

  4. significant role of DAP12 in the initial inflammatory response, bone remodeling and regeneration

  5. DAP12-mediated microglial activation following axotomy promotes pro-inflammatory responses, and thereby accelerates nerve injury-induced neuron death

  6. results support a role of DAP12 in stabilizing TREM2 (zeige TREM2 Antikörper)-CTF (zeige NFIA Antikörper), thereby protecting against excessive pro-inflammatory responses.

  7. a previously unrecognized role for DAP12 expression in tissue-resident alveolar macrophages in mediating acute noninfectious tissue injury through regulation of neutrophil trafficking.

  8. DAP12 expression in liver grafts regulates donor mDC (zeige ADAM11 Antikörper) migration to host lymphoid tissue, alloreactive T cell responses and transplant tolerance

  9. Integrin alphav beta3/Dap12 double-deficient developed profound osteoporosis.

  10. Our study identifies the DAP12/IRAK-M (zeige IRAK3 Antikörper)/IL-10 (zeige IL10 Antikörper) to be a novel molecular pathway in APCs (zeige APCS Antikörper) exploited by mycobacterial pathogens, allowing infection a foothold in the lung.

Cow (Bovine) TYRO Protein tyrosine Kinase Binding Protein (TYROBP) Interaktionspartner

TYROBP Antigen-Profil

Protein Überblick

This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene.

Genbezeichner und Symbole assoziert mit TYROBP

  • TYRO protein tyrosine kinase binding protein (TYROBP) Antikörper
  • TYRO protein tyrosine kinase binding protein (tyrobp) Antikörper
  • Tyro protein tyrosine kinase binding protein (Tyrobp) Antikörper
  • TYRO protein tyrosine kinase binding protein (Tyrobp) Antikörper
  • dap12 Antikörper
  • KARAP Antikörper
  • Ly83 Antikörper
  • PLOSL Antikörper
  • TYROBP Antikörper
  • tyrpbp Antikörper

Bezeichner auf Proteinebene für TYROBP

TYRO protein tyrosine kinase-binding protein , TYRO protein tyrosine kinase binding protein , DAP12 protein , dap12 , DAP12 , DNAX-activation protein 12 , killer cell activating receptor-associated protein , KAR-associated protein , killer activating receptor associated protein , killer-activating receptor-associated protein , killer cell activating receptor associated protein , immunoreceptor DAP12 , tyrosine kinase binding protein

GENE ID SPEZIES
476477 Canis lupus familiaris
443208 Ovis aries
100101461 Danio rerio
361537 Rattus norvegicus
7305 Homo sapiens
22177 Mus musculus
282390 Bos taurus
397405 Sus scrofa
574207 Macaca mulatta
455968 Pan troglodytes
Ausgewählte Anbieter für anti-TYROBP (TYROBP) Antikörper
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