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TYROBP Antikörper

TYROBP Reaktivität: Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7261337
  • Target Alle TYROBP Antikörper anzeigen
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    Reaktivität
    • 49
    • 19
    • 3
    Maus, Ratte
    Wirt
    • 65
    • 1
    • 1
    Kaninchen
    Klonalität
    • 58
    • 9
    Polyklonal
    Konjugat
    • 21
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser TYROBP Antikörper ist unkonjugiert
    Applikation
    • 41
    • 30
    • 26
    • 26
    • 21
    • 17
    • 12
    • 6
    • 4
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human TYROBP (NP_003323.1).
    Isotyp
    IgG
    Top Product
    Discover our top product TYROBP Primärantikörper
  • Applikationshinweise
    IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    Andere Bezeichnung
    TYROBP (TYROBP Produkte)
    Synonyme
    TYROBP antikoerper, DAP12 antikoerper, tyrpbp antikoerper, Karap antikoerper, KARAP antikoerper, PLOSL antikoerper, Ly83 antikoerper, dap12 antikoerper, TYRO protein tyrosine kinase binding protein antikoerper, Tyro protein tyrosine kinase binding protein antikoerper, TYROBP antikoerper, tyrobp antikoerper, Tyrobp antikoerper
    Hintergrund
    This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene.
    Gen-ID
    7305
    UniProt
    O43914
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