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TYROBP Antikörper (C-Term)

TYROBP Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB22347 unconjugated
Produktnummer ABIN653819
  • Target Alle TYROBP Antikörper anzeigen
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    Bindungsspezifität
    • 16
    • 15
    • 14
    • 10
    • 1
    • 1
    • 1
    • 1
    AA 85-113, C-Term
    Reaktivität
    • 48
    • 20
    • 4
    Human
    Wirt
    • 65
    • 1
    • 1
    Kaninchen
    Klonalität
    • 58
    • 9
    Polyklonal
    Konjugat
    • 21
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser TYROBP Antikörper ist unkonjugiert
    Applikation
    • 40
    • 29
    • 26
    • 26
    • 21
    • 18
    • 11
    • 6
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    B
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This TYROBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-113 amino acids from the C-terminal region of human TYROBP.
    Klon
    RB22347
    Isotyp
    IgG
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    Andere Bezeichnung
    TYROBP (TYROBP Produkte)
    Synonyme
    TYROBP antikoerper, DAP12 antikoerper, tyrpbp antikoerper, Karap antikoerper, KARAP antikoerper, PLOSL antikoerper, Ly83 antikoerper, dap12 antikoerper, TYRO protein tyrosine kinase binding protein antikoerper, Tyro protein tyrosine kinase binding protein antikoerper, TYROBP antikoerper, tyrobp antikoerper, Tyrobp antikoerper
    Hintergrund
    TYROBP encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL.
    Molekulargewicht
    12179
    Gen-ID
    7305
    NCBI Accession
    NP_001166985, NP_003323, NP_937758
    UniProt
    O43914
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