anti-SUMO1/sentrin Specific Protease 6 (SENP6) Antikörper

Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1\; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. Zusätzlich bieten wir Ihnen SENP6 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SENP6 215351 Q6P7W0
SENP6 26054 Q9GZR1
SENP6 300860  
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Top anti-SENP6 Antikörper auf antikoerper-online.de

Showing 10 out of 121 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-SENP6 Antibody Titration: 0.2-1 ug/mlPositive Control: 721_B cell lysate Sample Type: 1.Rat Testis cells (200ug) Primary Dilution: 1:1000Secondary Antibody: alkaline phosphatase-conjugated anti-rabbitSecondary Dilution: 1:1000Image Submitted by: Andreia CarvalhoIBMC-OBF, Portugal . 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of SENP6 polyclonal antibody (ABIN388052) in HL60 cell lysate. SENP6 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Ziege Unkonjugiert ELISA, WB ABIN334488 (0.5µg/ml) staining of HeLa cell nuclear lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: SENP6 Antibody [NBP1-00238] - Analysis of SENP6 in HeLa cell nuclear lysate (35ug protein in RIPA buffer) using NBP1-00238 at 0.5ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit Target Name: Senp6 Antibody Dilution: 1.0ug/ml Sample Type: Mouse Lung 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Human Kaninchen Unkonjugiert IHC (p) 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
385,00 €
Details
Human Ziege Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
Details
Human Maus Unkonjugiert IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to SENP6 on formalin-fixed paraffin-embedded human stomach. [antibody concentration 3 ug/ml] SENP6 monoclonal antibody (M01), clone 4B7 Western Blot analysis of SENP6 expression in IMR-32 . 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
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Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 3 bis 4 Tage
249,70 €
Details

SENP6 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-SENP6 Antikörper

  1. Human Polyclonal SENP6 Primary Antibody für IHC (p), WB - ABIN388052 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)
    Zeige alle 6 Referenzen für 388052

  2. Human Monoclonal SENP6 Primary Antibody für IHC (p), ELISA - ABIN565219 : Dou, Huang, Singh, Carpenter, Yeh: Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex. in Molecular cell 2010 (PubMed)
    Zeige alle 3 Referenzen für 565219

  3. Human Polyclonal SENP6 Primary Antibody für EIA, IHC (p) - ABIN356759 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Zeige alle 2 Referenzen für 356759

  4. Human Polyclonal SENP6 Primary Antibody für ELISA, WB - ABIN185077 : Kim, Baek, Jeon, Nishimori, Suzuki, Uchida, Shimbara, Saitoh, Tanaka, Chung: A new SUMO-1-specific protease, SUSP1, that is highly expressed in reproductive organs. in The Journal of biological chemistry 2000 (PubMed)

  5. Human Polyclonal SENP6 Primary Antibody für ELISA, WB - ABIN314340 : Choi, Chung, Rho, Lee, Lee, Choi, Seol, Baek, Bang, Chung: Negative modulation of RXRalpha transcriptional activity by small ubiquitin-related modifier (SUMO) modification and its reversal by SUMO-specific protease SUSP1. in The Journal of biological chemistry 2006 (PubMed)

  6. Cow (Bovine) Polyclonal SENP6 Primary Antibody für WB - ABIN2784245 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

Weitere Antikörper gegen SENP6 Interaktionspartner

Mouse (Murine) SUMO1/sentrin Specific Protease 6 (SENP6) Interaktionspartner

  1. Negative regulation of TLR inflammatory signaling by the SUMO-deconjugating enzyme SENP6.

Human SUMO1/sentrin Specific Protease 6 (SENP6) Interaktionspartner

  1. LANA could bind to the promoter region of the SENP6 gene and inhibit SENP6 expression while the regulated SENP6 could in turn modulate the abundance of LANA through desumoylation.

  2. the structure of SENP2 (zeige SUMO1 Antikörper)-Loop1 in complex with SUMO2 (zeige SUMO2 Antikörper) was solved at 2.15 A resolution, and reveals the details of an interface exclusive to SENP6/7 and the formation of unique contacts between both proteins

  3. Loop 1 insertion in SENP6 and SENP7 as a platform to discriminate between SUMO1 and SUMO2/3 isoforms in this subclass of the SUMO protease family.

  4. study of substrate specificity of SENP6; it is also capable of cleaving mixed chains of SUMO-1 (zeige SUMO1 Antikörper) and SUMO-2 (zeige SUMO2 Antikörper)/3; mutation of catalytic cysteine of results in its accumulation in PML (zeige PML Antikörper) NBs (zeige NBN Antikörper); findings indicate SUMO-modified PML (zeige PML Antikörper) is a substrate of SENP6

  5. Results reveal a novel mechanism whereby the finely balanced activities of SENP6 and RNF4 control vertebrate kinetochore assembly through SUMO-targeted destabilization of inner plate components.

  6. SENP1 (zeige SENP1 Antikörper) localization is influenced by expression and localization of SUMO-1 (zeige SUMO1 Antikörper)-conjugated target proteins within the cell.

  7. SUSP1 plays an important role in the control of the transcriptional activity of RXRalpha (zeige RXRA Antikörper) and thus in the RXRalpha (zeige RXRA Antikörper)-mediated cellular processes

  8. We have investigated the specificity of SUSP1 using vinyl sulfone inhibitors and model substrates. SUSP1 has a strong paralogue bias toward SUMO2 (zeige SUMO2 Antikörper)/3 and acts preferentially on substrates containing three or more SUMO2 (zeige SUMO2 Antikörper)/3 moieties

  9. SENP6 and SENP7 exhibit lower rates for processing pre-SUMO1, pre-SUMO2, or pre-SUMO3 in comparison with SENP2

SENP6 Antigen-Profil

Protein Überblick

Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1\; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA\; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins (Kim et al., 2000

Genbezeichner und Symbole assoziert mit SENP6

  • SUMO1/sentrin specific peptidase 6 (SENP6) Antikörper
  • SUMO/sentrin specific peptidase 6 (Senp6) Antikörper
  • SUMO1/sentrin specific peptidase 6 (Senp6) Antikörper
  • 2810017C20Rik Antikörper
  • E130319N12Rik Antikörper
  • mKIAA0797 Antikörper
  • SSP1 Antikörper
  • SUSP1 Antikörper

Bezeichner auf Proteinebene für SENP6

SUMO1/sentrin specific peptidase 6 , SUMO1/sentrin specific protease 6 , SUMO-1-specific protease 1 , SUMO/sentrin specific protease 6 , sentrin-specific protease 6 , sentrin/SUMO-specific protease SENP6 , 2810017C20Rik , SUMO/sentrin specific peptidase 6 , Sumo1/sentrin/SMT3 specific peptidase 6

GENE ID SPEZIES
462829 Pan troglodytes
215351 Mus musculus
481883 Canis lupus familiaris
26054 Homo sapiens
300860 Rattus norvegicus
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